STRINGSTRING
IL15 IL15 EGR1 EGR1 CCR9 CCR9 STAT6 STAT6 IL6ST IL6ST IL31RA IL31RA CX3CL1 CX3CL1 LOC100358749 LOC100358749 IKBKB IKBKB THPO THPO IL1R1 IL1R1 APPL1 APPL1 IL22RA1 IL22RA1 TNF TNF IL36G IL36G IL15RA IL15RA JAK1 JAK1 IL18RAP IL18RAP TRAF1 TRAF1 ACSL1 ACSL1 G1SPA3_RABIT G1SPA3_RABIT EPO EPO CNTF CNTF IL36RN IL36RN TNFRSF11A TNFRSF11A JAGN1 JAGN1 IL18 IL18 STAT5B STAT5B FLT3 FLT3 DOK1 DOK1 PYCARD PYCARD XCR1 XCR1 CXCR6 CXCR6 IL17F IL17F IL17A IL17A G1SL19_RABIT G1SL19_RABIT SMAD4 SMAD4 CD74 CD74 TRAF3 TRAF3 CCR2 CCR2 CCR1 CCR1 CD70 CD70 CSF2 CSF2 LIFR LIFR LOC100353390-2 LOC100353390-2 LYN LYN MKKS MKKS SH2B3 SH2B3 CCL5 CCL5 IRAK2 IRAK2 LOC100355421 LOC100355421 LOC100354397 LOC100354397 LOC100353390 LOC100353390 CXCR4 CXCR4 TNFRSF17 TNFRSF17 RIPK2 RIPK2 GFRA2 GFRA2 TP53 TP53 CCL20 CCL20 GPR75 GPR75 LOC100348776 LOC100348776 G1SDU7_RABIT G1SDU7_RABIT IL4R IL4R CCL24 CCL24 CXCR2 CXCR2 ENSOCUP00000049280 ENSOCUP00000049280 CXCL11 CXCL11 GFRA3 GFRA3 ENSOCUP00000048493 ENSOCUP00000048493 IFNAR1 IFNAR1 IRF1 IRF1 ENSOCUP00000047712 ENSOCUP00000047712 IL21R IL21R IL17RC IL17RC GFRA4 GFRA4 ST18 ST18 ENSOCUP00000046610 ENSOCUP00000046610 ILK ILK ENSOCUP00000045878 ENSOCUP00000045878 TNFRSF1A TNFRSF1A LOC100338113 LOC100338113 CNTFR CNTFR MPL MPL IL1RAP IL1RAP FZD4 FZD4 ENSOCUP00000043137 ENSOCUP00000043137 TRAF3IP2 TRAF3IP2 LOC100348748 LOC100348748 ENSOCUP00000041196 ENSOCUP00000041196 DUOX2 DUOX2 CCL25 CCL25 ENSOCUP00000040914 ENSOCUP00000040914 STAT2 STAT2 IL3RA IL3RA ENSOCUP00000039964 ENSOCUP00000039964 STAT1 STAT1 LOC100354910 LOC100354910 ENSOCUP00000039141 ENSOCUP00000039141 ENSOCUP00000039002 ENSOCUP00000039002 EDA2R EDA2R CCL19 CCL19 IL7 IL7 ENSOCUP00000037741 ENSOCUP00000037741 CCL7 CCL7 PLCB1 PLCB1 CCL4 CCL4 IL9R IL9R TYK2 TYK2 UGCG UGCG FER FER LOC103346238 LOC103346238 IL6R IL6R ENSOCUP00000035682 ENSOCUP00000035682 ENSOCUP00000035402 ENSOCUP00000035402 ENSOCUP00000035366 ENSOCUP00000035366 KIT KIT CSF1R CSF1R MYD88 MYD88 APPL2 APPL2 WNK1 WNK1 ENSOCUP00000033859 ENSOCUP00000033859 UMOD UMOD GHR GHR FCER1G FCER1G IL17RE IL17RE IL20RB IL20RB CXCR3 CXCR3 CSF3R CSF3R CLDN18 CLDN18 IRAK4 IRAK4 STAT4 STAT4 ENSOCUP00000031542 ENSOCUP00000031542 CHUK CHUK NMI NMI ENSOCUP00000030953 ENSOCUP00000030953 PRLR PRLR ENSOCUP00000030424 ENSOCUP00000030424 LOC100359182 LOC100359182 CSF2RA CSF2RA IRAK1 IRAK1 ENSOCUP00000029132 ENSOCUP00000029132 ADIPOR2 ADIPOR2 IFNE IFNE PDGFB PDGFB CXCR1 CXCR1 IL10RA IL10RA PLVAP PLVAP OASL OASL OASL-2 OASL-2 CXCL9 CXCL9 LIMS1 LIMS1 TRAF6 TRAF6 IL1RL2 IL1RL2 IFNLR1 IFNLR1 G1U9D6_RABIT G1U9D6_RABIT G1U940_RABIT G1U940_RABIT CSF1 CSF1 IFNGR2 IFNGR2 IL34 IL34 IL23R IL23R G1U7S6_RABIT G1U7S6_RABIT KRT18 KRT18 CX3CR1 CX3CR1 STAT5A STAT5A G1U1Z9_RABIT G1U1Z9_RABIT CCRL2 CCRL2 ENSOCUP00000023358 ENSOCUP00000023358 IL37 IL37 G1U0P1_RABIT G1U0P1_RABIT SIRT1 SIRT1 CCR6 CCR6 IL17RA IL17RA IFNK IFNK IL22RA2 IL22RA2 IL1B IL1B GFRAL GFRAL BBS4 BBS4 CCL21 CCL21 G1TU77_RABIT G1TU77_RABIT CCR10 CCR10 IFNB1 IFNB1 TREX1 TREX1 CXCL13 CXCL13 CCL17 CCL17 PPBP PPBP G1TQB6_RABIT G1TQB6_RABIT IL2RG IL2RG CCL14 CCL14 PTK2B PTK2B CXCR5 CXCR5 G1TN23_RABIT G1TN23_RABIT WBP1L WBP1L TOLLIP TOLLIP LOC100357194 LOC100357194 LOC100008885 LOC100008885 CDIP1 CDIP1 CCR5 CCR5 CCR7 CCR7 LOC100354654 LOC100354654 CSF2RB CSF2RB IL6 IL6 LOC100355669 LOC100355669 CNOT9 CNOT9 TNFSF18 TNFSF18 PIAS3 PIAS3 CIB1 CIB1 IFNAR2 IFNAR2 ACKR2 ACKR2 CCL2 CCL2 TNFSF11 TNFSF11 STK39 STK39 SYK SYK LEPR LEPR BBS2 BBS2 JAK2 JAK2 IL1R2 IL1R2 ACKR4 ACKR4 TXNDC17 TXNDC17 IL18R1 IL18R1 IL1RL1 IL1RL1 CD300LF CD300LF IL12B IL12B CXCL10 CXCL10 EREG EREG EPOR EPOR IL20RA IL20RA G1T9X6_RABIT G1T9X6_RABIT NFKBIA NFKBIA IL5RA IL5RA EDA EDA CCL22 CCL22 EXT1 EXT1 RABGEF1 RABGEF1 IL36A IL36A IL13RA2 IL13RA2 CAV1 CAV1 IL27RA IL27RA IRAK3 IRAK3 COMMD7 COMMD7 DUOX1 DUOX1 TNFRSF1B TNFRSF1B IL17RD IL17RD LOC100358223 LOC100358223 IL33 IL33 IL13RA1 IL13RA1 IL17RB IL17RB CCL1 CCL1 CCL13 CCL13 CTR9 CTR9 IFNGR1 IFNGR1 G1T4W9_RABIT G1T4W9_RABIT LOC100349255 LOC100349255 OSMR OSMR TNLG7A TNLG7A CCR8 CCR8 ZC3H15 ZC3H15 IL7R IL7R STAT3 STAT3 ACKR3 ACKR3 OSM OSM LEP LEP IRF5 IRF5 TNIP2 TNIP2 NUMBL NUMBL TRAF5 TRAF5 IL12RB2 IL12RB2 RPS6KA5 RPS6KA5 IL1A IL1A
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
IL15Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, which results in kinase SYK activation (By similarity). (162 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (700 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
IL31RAInterleukin 31 receptor A. (730 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (404 aa)
LOC100358749Sushi domain-containing protein. (272 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
THPOThrombopoietin. (348 aa)
IL1R1Interleukin 1 receptor type 1. (699 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (679 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
IL36GInterleukin-1. (170 aa)
IL15RASushi domain-containing protein. (262 aa)
JAK1Tyrosine-protein kinase. (1151 aa)
IL18RAPInterleukin 18 receptor accessory protein. (599 aa)
TRAF1TNF receptor-associated factor. (415 aa)
ACSL1Uncharacterized protein. (198 aa)
G1SPA3_RABITUncharacterized protein. (226 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (195 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (199 aa)
IL36RNInterleukin-1. (296 aa)
TNFRSF11ATNFR-Cys domain-containing protein. (349 aa)
JAGN1Jagunal homolog 1. (183 aa)
IL18Uncharacterized protein. (408 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
DOK1Docking protein 1. (484 aa)
PYCARDPYD and CARD domain containing. (196 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
CXCR6C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (455 aa)
IL17FInterleukin 17F. (163 aa)
IL17AInterleukin 17A. (153 aa)
G1SL19_RABITUncharacterized protein. (469 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CD74CD74 molecule. (375 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
CCR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CCR1Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (297 aa)
CSF2Uncharacterized protein. (144 aa)
LIFRLIF receptor subunit alpha. (1091 aa)
LOC100353390-2Uncharacterized protein. (190 aa)
LYNTyrosine-protein kinase. (636 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
SH2B3SH2B adaptor protein 3. (354 aa)
CCL5C-C motif chemokine. (91 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (592 aa)
LOC100355421Uncharacterized protein. (195 aa)
LOC100354397Uncharacterized protein. (195 aa)
LOC100353390Uncharacterized protein. (189 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa)
TNFRSF17TNF receptor superfamily member 17. (183 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
GFRA2GDNF family receptor alpha 2. (345 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa)
CCL20C-C motif chemokine. (96 aa)
GPR75G_PROTEIN_RECEP_F1_2 domain-containing protein. (539 aa)
LOC100348776C-C motif chemokine. (93 aa)
G1SDU7_RABITC-C motif chemokine. (104 aa)
IL4RFibronectin type-III domain-containing protein. (862 aa)
CCL24SCY domain-containing protein. (113 aa)
CXCR2C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2 (By similarity). (357 aa)
ENSOCUP00000049280SCY domain-containing protein. (136 aa)
CXCL11C-X-C motif chemokine ligand 11. (110 aa)
GFRA3GDNF family receptor alpha 3. (378 aa)
ENSOCUP00000048493Uncharacterized protein. (384 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (541 aa)
IRF1Interferon regulatory factor. (336 aa)
ENSOCUP00000047712Uncharacterized protein. (383 aa)
IL21RUncharacterized protein. (369 aa)
IL17RCInterleukin 17 receptor C. (770 aa)
GFRA4Uncharacterized protein. (513 aa)
ST18ST18 C2H2C-type zinc finger transcription factor. (1072 aa)
ENSOCUP00000046610Uncharacterized protein. (532 aa)
ILKIntegrin linked kinase. (510 aa)
ENSOCUP00000045878Uncharacterized protein. (279 aa)
TNFRSF1ATNF receptor superfamily member 1A. (472 aa)
LOC100338113Uncharacterized protein. (282 aa)
CNTFRCiliary neurotrophic factor receptor. (415 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
ENSOCUP00000043137Uncharacterized protein. (400 aa)
TRAF3IP2SEFIR domain-containing protein. (559 aa)
LOC100348748IGv domain-containing protein. (604 aa)
ENSOCUP00000041196Uncharacterized protein. (290 aa)
DUOX2Dual oxidase 2. (1545 aa)
CCL25SCY domain-containing protein. (159 aa)
ENSOCUP00000040914DUF953 domain-containing protein. (123 aa)
STAT2STAT_int domain-containing protein. (205 aa)
IL3RAUncharacterized protein. (394 aa)
ENSOCUP00000039964Uncharacterized protein. (191 aa)
STAT1Signal transducer and activator of transcription. (879 aa)
LOC100354910Uncharacterized protein. (187 aa)
ENSOCUP00000039141Ig-like domain-containing protein. (296 aa)
ENSOCUP00000039002Uncharacterized protein. (163 aa)
EDA2REctodysplasin A2 receptor. (332 aa)
CCL19C-C motif chemokine. (109 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
ENSOCUP00000037741Ig-like domain-containing protein. (418 aa)
CCL7SCY domain-containing protein. (204 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
CCL4C-C motif chemokine 4. (96 aa)
IL9RInterleukin 9 receptor. (576 aa)
TYK2Non-specific protein-tyrosine kinase. (1065 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (406 aa)
FERTyrosine-protein kinase. (452 aa)
LOC103346238Ig-like domain-containing protein. (517 aa)
IL6RInterleukin 6 receptor. (569 aa)
ENSOCUP00000035682Uncharacterized protein. (568 aa)
ENSOCUP00000035402Uncharacterized protein. (484 aa)
ENSOCUP00000035366IL17R_fnIII_D1 domain-containing protein. (331 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
MYD88Uncharacterized protein. (476 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (666 aa)
WNK1WNK lysine deficient protein kinase 1. (2853 aa)
ENSOCUP00000033859Uncharacterized protein. (176 aa)
UMODUromodulin. (794 aa)
GHRGrowth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). (692 aa)
FCER1GFc fragment of IgE receptor Ig. (85 aa)
IL17REInterleukin 17 receptor E. (762 aa)
IL20RBInterleukin 20 receptor subunit beta. (307 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (370 aa)
CSF3RColony stimulating factor 3 receptor. (1027 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (464 aa)
STAT4Signal transducer and activator of transcription. (752 aa)
ENSOCUP00000031542Ig-like domain-containing protein. (524 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (1057 aa)
NMIN-myc and STAT interactor. (367 aa)
ENSOCUP00000030953IRF tryptophan pentad repeat domain-containing protein. (200 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (640 aa)
ENSOCUP00000030424Uncharacterized protein. (516 aa)
LOC100359182Amino acid transporter. (665 aa)
CSF2RAFibronectin type-III domain-containing protein. (443 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (534 aa)
ENSOCUP00000029132C-X-C motif chemokine. (111 aa)
ADIPOR2Adiponectin receptor 2. (486 aa)
IFNEInterferon epsilon. (212 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (272 aa)
CXCR1C-X-C chemokine receptor type 1; Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. (355 aa)
IL10RAInterleukin 10 receptor subunit alpha. (540 aa)
PLVAPPlasmalemma vesicle associated protein. (437 aa)
OASL2'-5'-oligoadenylate synthetase like. (603 aa)
OASL-2Uncharacterized protein. (538 aa)
CXCL9C-X-C motif chemokine. (153 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa)
IL1RL2Interleukin 1 receptor like 2. (531 aa)
IFNLR1Interferon lambda receptor 1. (639 aa)
G1U9D6_RABITUncharacterized protein. (105 aa)
G1U940_RABITCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa)
CSF1Colony stimulating factor 1. (535 aa)
IFNGR2Interferon gamma receptor 2. (449 aa)
IL34Interleukin 34. (200 aa)
IL23RInterleukin 23 receptor. (622 aa)
G1U7S6_RABITUncharacterized protein. (209 aa)
KRT18IF rod domain-containing protein; Belongs to the intermediate filament family. (431 aa)
CX3CR1CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. (356 aa)
STAT5ASignal transducer and activator of transcription. (793 aa)
G1U1Z9_RABITUncharacterized protein. (242 aa)
CCRL2G_PROTEIN_RECEP_F1_2 domain-containing protein. (354 aa)
ENSOCUP00000023358annotation not available (195 aa)
IL37Interleukin-1. (280 aa)
G1U0P1_RABITUncharacterized protein. (209 aa)
SIRT1Sirtuin 1. (748 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
IL17RAInterleukin 17 receptor A. (860 aa)
IFNKInterferon kappa. (198 aa)
IL22RA2Interleukin 22 receptor subunit alpha 2. (231 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa)
GFRALGDNF family receptor alpha like. (555 aa)
BBS4Bardet-Biedl syndrome 4. (493 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
G1TU77_RABITUncharacterized protein. (160 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa)
IFNB1Interferon beta 1. (180 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
CXCL13C-X-C motif chemokine ligand 13. (105 aa)
CCL17SCY domain-containing protein. (106 aa)
PPBPUncharacterized protein. (82 aa)
G1TQB6_RABITUncharacterized protein. (134 aa)
IL2RGUncharacterized protein. (171 aa)
CCL14C-C motif chemokine ligand 14. (94 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
G1TN23_RABITSCY domain-containing protein. (116 aa)
WBP1LWW domain binding protein 1 like. (365 aa)
TOLLIPToll interacting protein. (274 aa)
LOC100357194Uncharacterized protein. (189 aa)
LOC100008885IF rod domain-containing protein; Belongs to the intermediate filament family. (418 aa)
CDIP1Cell death inducing p53 target 1. (208 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC100354654Uncharacterized protein. (189 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (868 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
LOC100355669Uncharacterized protein. (190 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
TNFSF18TNF superfamily member 18. (217 aa)
PIAS3Protein inhibitor of activated STAT 3. (520 aa)
CIB1Uncharacterized protein. (143 aa)
IFNAR2Uncharacterized protein. (523 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (401 aa)
CCL2C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (125 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
STK39Serine/threonine kinase 39. (544 aa)
SYKTyrosine-protein kinase. (630 aa)
LEPRLeptin receptor. (1164 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL1R2Interleukin 1 receptor type 2. (425 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
TXNDC17DUF953 domain-containing protein. (123 aa)
IL18R1Uncharacterized protein. (540 aa)
IL1RL1Interleukin 1 receptor like 1. (550 aa)
CD300LFCD300 molecule like family member f. (314 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa)
CXCL10C-X-C motif chemokine. (98 aa)
EREGEpiregulin. (169 aa)
EPORErythropoietin receptor. (554 aa)
IL20RAInterleukin 20 receptor subunit alpha. (548 aa)
G1T9X6_RABITUncharacterized protein. (188 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
IL5RAIL6Ra-bind domain-containing protein. (332 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (386 aa)
CCL22C-C motif chemokine. (93 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
RABGEF1Uncharacterized protein. (492 aa)
IL36AInterleukin-1. (156 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (361 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
IL27RAInterleukin 27 receptor subunit alpha. (634 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (593 aa)
COMMD7COMM domain-containing protein. (383 aa)
DUOX1Dual oxidase 1. (1586 aa)
TNFRSF1BTNF receptor superfamily member 1B. (425 aa)
IL17RDInterleukin 17 receptor D. (793 aa)
LOC100358223Uncharacterized protein. (195 aa)
IL33Uncharacterized protein. (142 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (519 aa)
IL17RBInterleukin 17 receptor B. (493 aa)
CCL1C-C motif chemokine. (190 aa)
CCL13C-C motif chemokine. (95 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
IFNGR1Interferon gamma receptor 1. (471 aa)
G1T4W9_RABITBaffR-Tall_bind domain-containing protein. (271 aa)
LOC100349255SCY domain-containing protein. (114 aa)
OSMROncostatin M receptor. (1088 aa)
TNLG7ATumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. (362 aa)
CCR8C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (355 aa)
ZC3H15Zinc finger CCCH-type containing 15. (426 aa)
IL7RInterleukin 7 receptor. (458 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (336 aa)
OSMUncharacterized protein. (333 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
IRF5Interferon regulatory factor 5. (500 aa)
TNIP2TNFAIP3 interacting protein 2. (314 aa)
NUMBLNUMB like endocytic adaptor protein. (672 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (883 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
IL1AInterleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (267 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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