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| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | IL4R | Fibronectin type-III domain-containing protein. (862 aa) |
| | PBRM1 | Polybromo 1. (1689 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | NFKBIZ | ANK_REP_REGION domain-containing protein. (714 aa) |
| | EGR3 | Early growth response 3. (386 aa) |
| | CD80 | T-lymphocyte activation antigen CD80; Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. (299 aa) |
| | HLA-DRA | Integral membrane protein; Belongs to the MHC class II family. (255 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (883 aa) |
| | IL15 | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, which results in kinase SYK activation (By similarity). (162 aa) |
| | ABL2 | Tyrosine-protein kinase. (1146 aa) |
| | HLA-DPB1 | RLA class II histocompatibility antigen, DP beta chain. (253 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | G1SV48_RABIT | Uncharacterized protein. (80 aa) |
| | CD27 | CD27 molecule. (260 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (844 aa) |
| | IL6ST | Interleukin 6 signal transducer. (918 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2343 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | EPHB6 | EPH receptor B6. (1015 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (404 aa) |
| | IL23A | Interleukin 23 subunit alpha. (191 aa) |
| | XBP1 | X-box binding protein 1. (208 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | GLI3 | GLI family zinc finger 3. (1575 aa) |
| | JAK1 | Tyrosine-protein kinase. (1151 aa) |
| | MMRN1 | Multimerin 1. (1211 aa) |
| | HLX | H2.0 like homeobox. (682 aa) |
| | LOC100348108 | AIG1-type G domain-containing protein. (312 aa) |
| | PDPN | Uncharacterized protein. (164 aa) |
| | DHPS | Uncharacterized protein. (369 aa) |
| | ZAP70 | Tyrosine-protein kinase. (623 aa) |
| | G1SPA3_RABIT | Uncharacterized protein. (226 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2089 aa) |
| | IL18 | Uncharacterized protein. (408 aa) |
| | G1SNC2_RABIT | Uncharacterized protein. (82 aa) |
| | STAT5B | Signal transducer and activator of transcription. (786 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (532 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (414 aa) |
| | ENSOCUP00000049280 | SCY domain-containing protein. (136 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (777 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (565 aa) |
| | SELENOK | Uncharacterized protein. (93 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (249 aa) |
| | KIFAP3 | Kinesin associated protein 3. (793 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (646 aa) |
| | TESPA1 | Thymocyte expressed, positive selection associated 1. (636 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1815 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (265 aa) |
| | CBFB | Uncharacterized protein. (82 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1060 aa) |
| | ENSOCUP00000046413 | MHC_II_beta domain-containing protein. (169 aa) |
| | TNFSF14 | TNF superfamily member 14. (241 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (978 aa) |
| | BCL6 | BCL6 transcription repressor. (723 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (695 aa) |
| | CD55 | Uncharacterized protein. (430 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1187 aa) |
| | LOC100338113 | Uncharacterized protein. (282 aa) |
| | ENSOCUP00000044347 | KH type-2 domain-containing protein. (196 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | LOC100349667 | Ig-like domain-containing protein. (292 aa) |
| | ADAM19 | ADAM metallopeptidase domain 19. (924 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1300 aa) |
| | CD6 | CD6 molecule. (683 aa) |
| | PLPP3 | acidPPc domain-containing protein. (331 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (332 aa) |
| | AFDN | Afadin, adherens junction formation factor. (1262 aa) |
| | PLAUR | Plasminogen activator, urokinase receptor. (365 aa) |
| | DNAJA3 | Uncharacterized protein. (479 aa) |
| | KIF26B | Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2030 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | LOC100355470 | Ig-like domain-containing protein. (326 aa) |
| | MAGI1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1358 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (525 aa) |
| | NFAT5 | Nuclear factor of activated T cells 5. (1554 aa) |
| | CCL19 | C-C motif chemokine. (109 aa) |
| | F11R | F11 receptor. (314 aa) |
| | ABL1 | Tyrosine-protein kinase. (1118 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (620 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (370 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa) |
| | LOC100350480 | Uncharacterized protein. (512 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (798 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (924 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (363 aa) |
| | LOC100357982 | BZIP domain-containing protein. (301 aa) |
| | TYK2 | Non-specific protein-tyrosine kinase. (1065 aa) |
| | IGFBP2 | IGFBP N-terminal domain-containing protein. (442 aa) |
| | GCNT2 | Uncharacterized protein. (402 aa) |
| | ENSOCUP00000033540 | Ig-like domain-containing protein. (203 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (276 aa) |
| | ARID1B | AT-rich interaction domain 1B. (1600 aa) |
| | SOX13 | SRY-box transcription factor 13. (663 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1595 aa) |
| | MALT1 | MALT1 paracaspase. (799 aa) |
| | FGG | Fibrinogen gamma chain. (450 aa) |
| | CD274 | CD274 molecule. (302 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | ENSOCUP00000031376 | Uncharacterized protein. (95 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (534 aa) |
| | ENSOCUP00000029650 | Uncharacterized protein. (212 aa) |
| | SHB | SH2 domain-containing protein. (607 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (762 aa) |
| | LOC100352672 | Ig-like domain-containing protein; Belongs to the MHC class II family. (382 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1207 aa) |
| | MFSD2B | Uncharacterized protein. (672 aa) |
| | LOC103350560 | Uncharacterized protein. (343 aa) |
| | EFNB3 | Ephrin B3; Belongs to the ephrin family. (486 aa) |
| | LOC100350239 | Uncharacterized protein. (423 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (531 aa) |
| | LOC100343144 | Ig-like domain-containing protein; Belongs to the MHC class II family. (279 aa) |
| | SELE | E-selectin; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis; Belongs to the selectin/LECAM family. (602 aa) |
| | IL23R | Interleukin 23 receptor. (622 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. (255 aa) |
| | ETS1 | Uncharacterized protein. (533 aa) |
| | MYO10 | Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2067 aa) |
| | STAT5A | Signal transducer and activator of transcription. (793 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (340 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | G1U289_RABIT | Uncharacterized protein. (472 aa) |
| | CD5 | Uncharacterized protein. (488 aa) |
| | G1U0P1_RABIT | Uncharacterized protein. (209 aa) |
| | SIRPA | Uncharacterized protein. (563 aa) |
| | CD276 | Uncharacterized protein. (286 aa) |
| | HAS2 | Uncharacterized protein. (556 aa) |
| | ZP4 | Processed zona pellucida sperm-binding protein 4; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor; Belongs to the ZP domain family. ZPB subfamily. (540 aa) |
| | BMP7 | TGF_BETA_2 domain-containing protein. (170 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (279 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa) |
| | RLA-DMB | Ig-like domain-containing protein. (257 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa) |
| | DMTN | Dematin actin binding protein. (424 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] (506 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | RNASE10 | Ribonuclease A family member 10 (inactive); Belongs to the pancreatic ribonuclease family. (221 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa) |
| | PTPRU | Protein tyrosine phosphatase receptor type U. (1321 aa) |
| | CXCL13 | C-X-C motif chemokine ligand 13. (105 aa) |
| | LOC100344662 | Uncharacterized protein. (469 aa) |
| | LGALS1 | Galectin. (134 aa) |
| | IL2RG | Uncharacterized protein. (171 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (549 aa) |
| | G1TLQ5_RABIT | Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (245 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | CHST2 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (401 aa) |
| | SART1 | Uncharacterized protein. (160 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (334 aa) |
| | RARA | Retinoic acid receptor alpha. (462 aa) |
| | G1TH84_RABIT | AIG1-type G domain-containing protein. (194 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (234 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (495 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (441 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | SYK | Tyrosine-protein kinase. (630 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | TFRC | Transferrin receptor. (763 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa) |
| | NFKBID | NFKB inhibitor delta. (328 aa) |
| | SELP | Uncharacterized protein. (768 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa) |
| | VSIR | V-set immunoregulatory receptor. (312 aa) |
| | ZP3 | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (419 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (154 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (634 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (339 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (324 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1181 aa) |
| | ARID2 | AT-rich interaction domain 2. (1772 aa) |
| | G1T4W9_RABIT | BaffR-Tall_bind domain-containing protein. (271 aa) |
| | LOC100349255 | SCY domain-containing protein. (114 aa) |
| | HSPD1 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | ST3GAL4 | Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (341 aa) |
| | TNLG7A | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. (362 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (758 aa) |
| | IL7R | Interleukin 7 receptor. (458 aa) |
| | FGA | Fibrinogen alpha chain. (813 aa) |
| | FGB | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (492 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1044 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | FOXP3 | Forkhead box P3. (455 aa) |
| | ADA | Adenosine deaminase. (363 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (153 aa) |
| | CHST4 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (389 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | CD74 | CD74 molecule. (375 aa) |
| | MEGF10 | Multiple EGF like domains 10. (1130 aa) |
| | ANK3 | Ankyrin 3. (4364 aa) |
| | CD83 | CD83 molecule. (292 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2102 aa) |
| | PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1630 aa) |
| | EMILIN2 | Elastin microfibril interfacer 2. (1133 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 1. (305 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1011 aa) |
| | ICOS | Inducible T cell costimulator. (222 aa) |
| | SKAP1 | Src kinase associated phosphoprotein 1. (358 aa) |
| | CTSG | Cathepsin G. (250 aa) |
| | GP1BA | Glycoprotein Ib platelet subunit alpha. (615 aa) |
| | DENND6A | DENN domain containing 6A. (608 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (636 aa) |
