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SIRT1 | Sirtuin 1. (748 aa) | ||||
G1U940_RABIT | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa) | ||||
LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) | ||||
ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) | ||||
ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) | ||||
RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (475 aa) | ||||
C12H6orf89 | Uncharacterized protein. (311 aa) | ||||
JDP2 | Jun dimerization protein 2. (184 aa) | ||||
ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) | ||||
BCL6 | BCL6 transcription repressor. (723 aa) | ||||
ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa) | ||||
PML | Promyelocytic leukemia. (860 aa) | ||||
AKAP8 | A-kinase anchoring protein 8; Belongs to the AKAP95 family. (665 aa) | ||||
NIPBL | Nipped-B protein. (2580 aa) | ||||
PINK1 | PTEN induced kinase 1. (569 aa) | ||||
LRRK2 | Leucine rich repeat kinase 2. (2499 aa) | ||||
G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
SDR16C5 | Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa) | ||||
AKAP8L | A-kinase anchoring protein 8 like; Belongs to the AKAP95 family. (633 aa) | ||||
ING2 | Inhibitor of growth protein. (283 aa) | ||||
SAP30BP | SAP30 binding protein. (365 aa) | ||||
G1TIG1_RABIT | Uncharacterized protein. (421 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) | ||||
APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (870 aa) | ||||
LOC100357467 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (335 aa) |