28 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	PLA2G10	Phospholipase A(2). (163 aa)
	INTU	Inturned planar cell polarity protein. (944 aa)
	FST	Follistatin. (310 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	NGFR	Nerve growth factor receptor. (407 aa)
	DLX3	Distal-less homeobox 3. (287 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
	KRT25	Keratin 25; Belongs to the intermediate filament family. (450 aa)
	SOSTDC1	Sclerostin domain containing 1. (206 aa)
	ATP7A	ATPase copper transporting alpha. (1499 aa)
	KRT28	Keratin 28; Belongs to the intermediate filament family. (459 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa)
	GORAB	Golgin, RAB6 interacting. (394 aa)
	SNAI1	Snail family transcriptional repressor 1. (238 aa)
	PLA2G10-2	Phospholipase A(2). (152 aa)
	IGFBP5	Insulin like growth factor binding protein 5. (271 aa)
	KRT71	Keratin 71; Belongs to the intermediate filament family. (523 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
	TMEM79	Uncharacterized protein. (504 aa)
	CTNNB1	Catenin beta 1. (741 aa)
	FGFR2	Fibroblast growth factor receptor. (894 aa)
	BCL2	BH4_2 domain-containing protein. (389 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	GLI2	GLI family zinc finger 2. (1575 aa)
	LOC100352102	Uncharacterized protein. (256 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	CTNNB1	ENSOCUP00000036189	ENSOCUP00000032985	BH4_2 domain-containing protein.	Catenin beta 1.	0.481
BCL2	FGF10	ENSOCUP00000036189	ENSOCUP00000007347	BH4_2 domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.436
BCL2	FGF7	ENSOCUP00000036189	ENSOCUP00000037580	BH4_2 domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.453
BCL2	GLI2	ENSOCUP00000036189	ENSOCUP00000047570	BH4_2 domain-containing protein.	GLI family zinc finger 2.	0.445
BCL2	SHH	ENSOCUP00000036189	ENSOCUP00000014488	BH4_2 domain-containing protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.483
BCL2	SMO	ENSOCUP00000036189	ENSOCUP00000027051	BH4_2 domain-containing protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.427
BCL2	SNAI1	ENSOCUP00000036189	ENSOCUP00000016651	BH4_2 domain-containing protein.	Snail family transcriptional repressor 1.	0.432
CTNNB1	BCL2	ENSOCUP00000032985	ENSOCUP00000036189	Catenin beta 1.	BH4_2 domain-containing protein.	0.481
CTNNB1	FGF10	ENSOCUP00000032985	ENSOCUP00000007347	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.400
CTNNB1	FGFR2	ENSOCUP00000032985	ENSOCUP00000034244	Catenin beta 1.	Fibroblast growth factor receptor.	0.663
CTNNB1	LOC100352102	ENSOCUP00000032985	ENSOCUP00000048013	Catenin beta 1.	Uncharacterized protein.	0.428
CTNNB1	SHH	ENSOCUP00000032985	ENSOCUP00000014488	Catenin beta 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.553
CTNNB1	SMO	ENSOCUP00000032985	ENSOCUP00000027051	Catenin beta 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.416
CTNNB1	SNAI1	ENSOCUP00000032985	ENSOCUP00000016651	Catenin beta 1.	Snail family transcriptional repressor 1.	0.551
CTNNB1	WNT10A	ENSOCUP00000032985	ENSOCUP00000013780	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.410
DLX3	SHH	ENSOCUP00000006768	ENSOCUP00000014488	Distal-less homeobox 3.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.426
FGF10	BCL2	ENSOCUP00000007347	ENSOCUP00000036189	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	BH4_2 domain-containing protein.	0.436
FGF10	CTNNB1	ENSOCUP00000007347	ENSOCUP00000032985	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Catenin beta 1.	0.400
FGF10	FGF7	ENSOCUP00000007347	ENSOCUP00000037580	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.496
FGF10	FGFR2	ENSOCUP00000007347	ENSOCUP00000034244	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.999