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| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4806 aa) |
| | SPOPL | Speckle type BTB/POZ protein like. (392 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family. (117 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (265 aa) |
| | G1SSE7_RABIT | Uncharacterized protein; Belongs to the peptidase C14A family. (306 aa) |
| | NGFR | Nerve growth factor receptor. (407 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (607 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1847 aa) |
| | BAG6 | BCL2 associated athanogene 6. (1162 aa) |
| | TXNIP | Thioredoxin interacting protein. (429 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1300 aa) |
| | ENSOCUP00000044498 | Ribosomal_L40e domain-containing protein. (152 aa) |
| | ENSOCUP00000044611 | Uncharacterized protein. (1515 aa) |
| | FAF2 | Fas associated factor family member 2. (445 aa) |
| | TRIOBP | PH domain-containing protein. (904 aa) |
| | FAM178B | Uncharacterized protein. (460 aa) |
| | TMBIM6 | Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (306 aa) |
| | GLMN | Uncharacterized protein. (592 aa) |
| | CUL7 | Cullin 7; Belongs to the cullin family. (1728 aa) |
| | LTBR | Lymphotoxin beta receptor. (414 aa) |
| | UBB | Ubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11- [...] (288 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa) |
| | UBE2J2 | Ubiquitin conjugating enzyme E2 J2. (252 aa) |
| | G1SED3_RABIT | Uncharacterized protein. (590 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (731 aa) |
| | CAMLG | Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (292 aa) |
| | LOC100354435 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (611 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (780 aa) |
| | SNCAIP | Synuclein alpha interacting protein. (918 aa) |
| | TNK2 | Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (853 aa) |
| | BAG1 | Uncharacterized protein. (354 aa) |
| | BLZF1 | Basic leucine zipper nuclear factor 1. (401 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) |
| | RPL5 | 60S ribosomal protein L5. (297 aa) |
| | ELOB | Elongin B. (118 aa) |
| | UBE2T | Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (197 aa) |
| | PSMA3 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (326 aa) |
| | G1SZ30_RABIT | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1193 aa) |
| | G1SZF4_RABIT | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | DAXX | Death domain associated protein. (740 aa) |
| | CUL5 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] (780 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1688 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | ARIH1 | RBR-type E3 ubiquitin transferase. (500 aa) |
| | LOC100343655 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (670 aa) |
| | FHIT | HIT domain-containing protein. (173 aa) |
| | PRR5L | Proline rich 5 like. (368 aa) |
| | RTN4 | Reticulon. (1110 aa) |
| | UBXN7 | UBX domain-containing protein. (526 aa) |
| | HSPD1 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (421 aa) |
| | UBASH3B | Ubiquitin associated and SH3 domain containing B. (649 aa) |
| | PACRG | Parkin coregulated. (257 aa) |
| | ERLIN2 | ER lipid raft associated 2. (439 aa) |
| | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa) |
| | EGR2 | Early growth response 2. (549 aa) |
| | LAPTM4B | Lysosomal protein transmembrane 4 beta. (226 aa) |
| | RPL23 | Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family. (140 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (425 aa) |
| | DBT | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa) |
| | YOD1 | YOD1 deubiquitinase. (348 aa) |
| | FOXO1 | Fork-head domain-containing protein. (613 aa) |
| | G1T7C8_RABIT | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (145 aa) |
| | CUL2 | Cullin 2; Belongs to the cullin family. (745 aa) |
| | LRPPRC | Leucine rich pentatricopeptide repeat containing. (1457 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (409 aa) |
| | BAG4 | BCL2 associated athanogene 4. (459 aa) |
| | SQSTM1 | Sequestosome 1. (518 aa) |
| | CACUL1 | CDK2 associated cullin domain 1. (346 aa) |
| | APC | APC regulator of WNT signaling pathway. (2871 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | CDKN1A | Uncharacterized protein. (231 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (210 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | TRIM28 | Tripartite motif containing 28. (857 aa) |
| | TMEM52B | Uncharacterized protein. (295 aa) |
| | ASB4 | Ankyrin repeat and SOCS box containing 4. (426 aa) |
| | DLG3 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa) |
| | UBXN1 | UBX domain protein 1. (297 aa) |
| | SMC6 | Uncharacterized protein. (927 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1339 aa) |
| | PA2G4 | Peptidase_M24 domain-containing protein. (394 aa) |
| | DET1 | Uncharacterized protein. (553 aa) |
| | ARRDC1 | Arrestin domain containing 1. (429 aa) |
| | SPART | Spartin. (679 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (402 aa) |
| | CHEK2 | Checkpoint kinase 2. (538 aa) |
| | G1TG12_RABIT | Small ubiquitin-related modifier. (87 aa) |
| | G1TGC0_RABIT | Uncharacterized protein. (214 aa) |
| | TCP1 | Uncharacterized protein. (556 aa) |
| | RTN3 | Reticulon. (977 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | KCNH2 | Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1108 aa) |
| | TRAF4 | TNF receptor-associated factor. (470 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (252 aa) |
| | ENSOCUP00000033272 | Uncharacterized protein. (89 aa) |
| | ENSOCUP00000033398 | Uncharacterized protein. (66 aa) |
| | SUMO1 | Small ubiquitin-related modifier. (101 aa) |
| | CD40 | Uncharacterized protein. (494 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | ENSOCUP00000034763 | Uncharacterized protein. (95 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (860 aa) |
| | LOC100353293 | Uncharacterized protein. (321 aa) |
| | FBXO7 | F-box domain-containing protein. (583 aa) |
| | ZNF746 | Zinc finger protein 746. (789 aa) |
| | ATF6 | Activating transcription factor 6. (772 aa) |
| | LOC100343047 | Ubiquitin-like domain-containing protein. (77 aa) |
| | SMG5 | SMG5 nonsense mediated mRNA decay factor. (1151 aa) |
| | JKAMP | Uncharacterized protein. (362 aa) |
| | BCL2 | BH4_2 domain-containing protein. (389 aa) |
| | ENSOCUP00000036387 | DIX domain-containing protein. (575 aa) |
| | ENSOCUP00000036823 | Mitogen-activated protein kinase. (254 aa) |
| | RNF8 | Ring finger protein 8. (500 aa) |
| | SCAMP3 | Secretory carrier-associated membrane protein. (349 aa) |
| | LOC100341293 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (444 aa) |
| | ENSOCUP00000038446 | Ubiquitin-like domain-containing protein. (87 aa) |
| | mc1R | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (307 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (324 aa) |
| | ENSOCUP00000039146 | Uncharacterized protein. (151 aa) |
| | VCL | Vinculin. (1241 aa) |
| | ENSOCUP00000039489 | Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (77 aa) |
| | STX8 | t-SNARE coiled-coil homology domain-containing protein. (125 aa) |
| | CASC3 | CASC3 exon junction complex subunit. (742 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (901 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like. (414 aa) |
| | SYT11 | Synaptotagmin 11. (440 aa) |
| | SH3KBP1 | SH3 domain containing kinase binding protein 1. (717 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (352 aa) |
| | ENSOCUP00000040990 | Josephin domain-containing protein. (123 aa) |
| | G1TXZ4_RABIT | Uncharacterized protein. (975 aa) |
| | PARK2 | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (394 aa) |
| | UBOX5 | U-box domain containing 5. (541 aa) |
| | G1TZL0_RABIT | Ubiquitin-like domain-containing protein. (171 aa) |
| | AICDA | Activation induced cytidine deaminase. (198 aa) |
| | MC4R | Melanocortin 4 receptor. (333 aa) |
| | RALA-2 | Uncharacterized protein. (206 aa) |
| | G1U1I7_RABIT | Uncharacterized protein. (91 aa) |
| | MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1. (1052 aa) |
| | RTN2 | Reticulon. (499 aa) |
| | G1U317_RABIT | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | FZD8 | G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (303 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (623 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (401 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (323 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (206 aa) |
| | G1U940_RABIT | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa) |
| | PDLIM2 | Uncharacterized protein. (400 aa) |
| | G1TLZ6_RABIT | Uncharacterized protein. (168 aa) |
| | GON7 | Uncharacterized protein. (101 aa) |
| | G1TMJ4_RABIT | SH3 domain-containing protein. (161 aa) |
| | TOLLIP | Toll interacting protein. (274 aa) |
| | WBP1L | WW domain binding protein 1 like. (365 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (549 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | RANGAP1 | Ran GTPase activating protein 1. (630 aa) |
| | LOC100341783 | Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family. (140 aa) |
| | RNF40 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1000 aa) |
| | DDX58 | DExD/H-box helicase 58. (954 aa) |
| | MAP1LC3B | Uncharacterized protein. (339 aa) |
| | G1TR69_RABIT | Uncharacterized protein. (169 aa) |
| | G1TRC0_RABIT | Uncharacterized protein; Belongs to the heat shock protein 70 family. (681 aa) |
| | ARRB1 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] (408 aa) |
| | PAX6 | Uncharacterized protein. (436 aa) |
| | TPI1 | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (288 aa) |
| | G1TSW1_RABIT | Ubiquitin-like domain-containing protein. (62 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (469 aa) |
| | UBE2L6 | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | G1TVD5_RABIT | Uncharacterized protein. (101 aa) |
| | ANKRA2 | Ankyrin repeat family A member 2. (313 aa) |
| | NAE1 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (537 aa) |
| | SMAD3 | SMAD family member 3. (230 aa) |
| | ENSOCUP00000027364 | Uncharacterized protein. (89 aa) |
| | ISG15 | ISG15 ubiquitin like modifier. (164 aa) |
| | PIAS2 | Protein inhibitor of activated STAT 2; Belongs to the glycosyltransferase 29 family. (911 aa) |
| | NPLOC4 | NPL4 homolog, ubiquitin recognition factor. (576 aa) |
| | STING1 | Transmembrane protein 173. (426 aa) |
| | RAD18 | Uncharacterized protein. (578 aa) |
| | ENSOCUP00000029790 | Uncharacterized protein. (160 aa) |
| | G1TLX8_RABIT | RING-type domain-containing protein. (248 aa) |
| | G1TLL0_RABIT | Uncharacterized protein. (667 aa) |
| | PER1 | Period circadian regulator 1. (1203 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa) |
| | G1TJY5_RABIT | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (186 aa) |
| | HSPBP1 | HSPA (Hsp70) binding protein 1. (427 aa) |
| | ENSOCUP00000030134 | Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (340 aa) |
| | ENSOCUP00000030338 | Uncharacterized protein. (228 aa) |
| | ENSOCUP00000030467 | Uncharacterized protein. (229 aa) |
| | ENSOCUP00000030650 | Rad60-SLD domain-containing protein. (173 aa) |
| | NEK6 | Protein kinase domain-containing protein. (547 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (771 aa) |
| | ENSOCUP00000031387 | Uncharacterized protein. (326 aa) |
| | SPOP | Speckle type BTB/POZ protein. (407 aa) |
| | HM13 | Histocompatibility minor 13. (498 aa) |
| | SNX9 | Sorting nexin 9. (647 aa) |
| | UBE2B | Ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (228 aa) |
| | TSG101 | Tumor susceptibility 101. (422 aa) |
| | RNF34 | Ring finger protein 34. (454 aa) |
| | LOC100344315 | Uncharacterized protein. (229 aa) |
| | UBE2D1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (916 aa) |
| | ENSOCUP00000032919 | RGS domain-containing protein. (291 aa) |
| | UCHL1 | Ubiquitin carboxyl-terminal hydrolase. (237 aa) |
| | RB1 | RB transcriptional corepressor 1. (943 aa) |
| | HIF1A | Uncharacterized protein. (851 aa) |
| | ENSOCUP00000041191 | Uncharacterized protein. (53 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (934 aa) |
| | MAP1LC3C | Uncharacterized protein. (156 aa) |
| | EIF4E2 | Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (328 aa) |
| | WASHC1 | WH2 domain-containing protein. (666 aa) |
| | APBB1 | Amyloid beta precursor protein binding family B member 1. (777 aa) |
| | FAF1 | Fas associated factor 1. (616 aa) |
| | RALA | Uncharacterized protein. (263 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (436 aa) |
| | ABI2 | Uncharacterized protein. (540 aa) |
| | UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (539 aa) |
| | ENSOCUP00000046059 | Uncharacterized protein. (213 aa) |
| | ENSOCUP00000046087 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa) |
| | AXIN2 | Axin 2. (816 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | CCT2 | Uncharacterized protein. (576 aa) |
| | UBASH3A | Ubiquitin associated and SH3 domain containing A. (757 aa) |
| | ENSOCUP00000047538 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (121 aa) |
| | ENSOCUP00000047714 | Ubiquitin-like domain-containing protein. (71 aa) |
| | CCDC50 | Coiled-coil domain containing 50. (509 aa) |
| | PCBP2 | Poly(rC) binding protein 2. (366 aa) |
| | ENSOCUP00000048361 | Uncharacterized protein. (100 aa) |
| | ENSOCUP00000048602 | Ribosomal_L18_c domain-containing protein. (169 aa) |
| | HDAC6 | Histone deacetylase 6. (1257 aa) |
| | ENSOCUP00000049359 | Uncharacterized protein. (349 aa) |
| | ENSOCUP00000049796 | Uncharacterized protein. (161 aa) |
| | FANCL | FA complementation group L. (414 aa) |
| | ENSOCUP00000049978 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (100 aa) |
| | ENSOCUP00000042868 | RBR-type E3 ubiquitin transferase. (139 aa) |
| | TRIM37 | Tripartite motif containing 37. (967 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | UBE2G1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (145 aa) |
| | LOC100347883 | Uncharacterized protein. (212 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1161 aa) |
| | GPR37 | G protein-coupled receptor 37. (614 aa) |
| | HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (733 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (361 aa) |
| | PINK1 | PTEN induced kinase 1. (569 aa) |
| | JAK1 | Tyrosine-protein kinase. (1151 aa) |
| | SMAD6 | MH2 domain-containing protein. (220 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (845 aa) |
| | CLU | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (518 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) |
| | ATXN3 | Josephin domain-containing protein. (363 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | UBE2J1 | Ubiquitin conjugating enzyme E2 J1. (318 aa) |
| | USP19 | Ubiquitin specific peptidase 19. (1379 aa) |
| | USP25 | Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1152 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1015 aa) |
| | KDM4A | Uncharacterized protein. (1064 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1852 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | G1SK22_RABIT | Ubiquitin-like domain-containing protein. (188 aa) |
| | TRIB2 | Tribbles pseudokinase 2. (343 aa) |
| | LYN | Tyrosine-protein kinase. (636 aa) |
| | G1SIQ0_RABIT | UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa) |
| | CUL9 | Cullin 9; Belongs to the cullin family. (2580 aa) |
| | NEDD8 | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). (81 aa) |
| | SLF2 | SMC5-SMC6 complex localization factor 2. (1167 aa) |
| | UBE2L3 | Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (211 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (775 aa) |
| | PATZ1 | POZ and AT hook containing zinc finger 1 long C isoform (Predicted). (687 aa) |
| | PACRGL | Uncharacterized protein. (248 aa) |
| | PML | Promyelocytic leukemia. (860 aa) |
