16 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P2RY8	P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	F2RL1	F2R like trypsin receptor 1. (397 aa)
	CRP	C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). (225 aa)
	IL18	Uncharacterized protein. (408 aa)
	G1SV95_RABIT	Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
	HVCN1	Hydrogen voltage gated channel 1. (316 aa)
	CLEC7A	C-type lectin domain containing 7A. (247 aa)
	SYK	Tyrosine-protein kinase. (630 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
	PRKCD	Uncharacterized protein. (807 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	ITGB2	Integrin beta. (1009 aa)
	ENSOCUP00000041840	TGFb_propeptide domain-containing protein. (219 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)
	ENSOCUP00000045925	TGFb_propeptide domain-containing protein. (272 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLEC7A	SYK	ENSOCUP00000014442	ENSOCUP00000015068	C-type lectin domain containing 7A.	Tyrosine-protein kinase.	0.979
CRP	IL18	ENSOCUP00000004059	ENSOCUP00000004555	C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity).	Uncharacterized protein.	0.710
ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000037329	IL18	ENSOCUP00000037329	ENSOCUP00000004555	TGFb_propeptide domain-containing protein.	Uncharacterized protein.	0.424
ENSOCUP00000037329	ITGB2	ENSOCUP00000037329	ENSOCUP00000040076	TGFb_propeptide domain-containing protein.	Integrin beta.	0.482
ENSOCUP00000037329	LOC103345451	ENSOCUP00000037329	ENSOCUP00000031740	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.419
ENSOCUP00000041840	ITGB2	ENSOCUP00000041840	ENSOCUP00000040076	TGFb_propeptide domain-containing protein.	Integrin beta.	0.482
ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000044284	IL18	ENSOCUP00000044284	ENSOCUP00000004555	TGFb_propeptide domain-containing protein.	Uncharacterized protein.	0.424
ENSOCUP00000044284	ITGB2	ENSOCUP00000044284	ENSOCUP00000040076	TGFb_propeptide domain-containing protein.	Integrin beta.	0.482
ENSOCUP00000045925	ITGB2	ENSOCUP00000045925	ENSOCUP00000040076	TGFb_propeptide domain-containing protein.	Integrin beta.	0.482
G1SV95_RABIT	ITGB2	ENSOCUP00000007334	ENSOCUP00000040076	Transforming growth factor beta; Belongs to the TGF-beta family.	Integrin beta.	0.482
IL18	CRP	ENSOCUP00000004555	ENSOCUP00000004059	Uncharacterized protein.	C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity).	0.710
IL18	ENSOCUP00000037329	ENSOCUP00000004555	ENSOCUP00000037329	Uncharacterized protein.	TGFb_propeptide domain-containing protein.	0.424
IL18	ENSOCUP00000044284	ENSOCUP00000004555	ENSOCUP00000044284	Uncharacterized protein.	TGFb_propeptide domain-containing protein.	0.424
IL18	LOC103345451	ENSOCUP00000004555	ENSOCUP00000031740	Uncharacterized protein.	TGFb_propeptide domain-containing protein.	0.424
IL18	SYK	ENSOCUP00000004555	ENSOCUP00000015068	Uncharacterized protein.	Tyrosine-protein kinase.	0.433
ITGB2	ENSOCUP00000037329	ENSOCUP00000040076	ENSOCUP00000037329	Integrin beta.	TGFb_propeptide domain-containing protein.	0.482
ITGB2	ENSOCUP00000041840	ENSOCUP00000040076	ENSOCUP00000041840	Integrin beta.	TGFb_propeptide domain-containing protein.	0.482
ITGB2	ENSOCUP00000044284	ENSOCUP00000040076	ENSOCUP00000044284	Integrin beta.	TGFb_propeptide domain-containing protein.	0.482