STRINGSTRING
G1SV95_RABIT G1SV95_RABIT PIWIL2 PIWIL2 SMAD4 SMAD4 BRCA1 BRCA1 PIH1D1 PIH1D1 RUVBL2 RUVBL2 G1TML2_RABIT G1TML2_RABIT LIF LIF GATA3 GATA3 TADA2A TADA2A KAT2A KAT2A SNAI2 SNAI2 G1TMM4_RABIT G1TMM4_RABIT ENSOCUP00000045925 ENSOCUP00000045925 ARID5A ARID5A GLYR1 GLYR1 ENSOCUP00000044284 ENSOCUP00000044284 ENSOCUP00000043169 ENSOCUP00000043169 ENSOCUP00000041840 ENSOCUP00000041840 ENSOCUP00000040876 ENSOCUP00000040876 ERCC6 ERCC6 SMARCB1 SMARCB1 ENSOCUP00000037329 ENSOCUP00000037329 ENSOCUP00000033150 ENSOCUP00000033150 LOC103345451 LOC103345451 KAT7 KAT7 BAZ1B BAZ1B G1TVW2_RABIT G1TVW2_RABIT SF3B1 SF3B1 ISL1 ISL1 BRD7 BRD7 ARRB1 ARRB1 FOXP3 FOXP3 RPS6KA5 RPS6KA5 AUTS2 AUTS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (971 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1852 aa)
PIH1D1PIH1 domain containing 1. (291 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
G1TML2_RABITSEA domain-containing protein. (455 aa)
LIFLIF interleukin 6 family cytokine. (203 aa)
GATA3GATA binding protein 3. (444 aa)
TADA2ATranscriptional adapter. (443 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (795 aa)
SNAI2Uncharacterized protein. (268 aa)
G1TMM4_RABITUncharacterized protein. (266 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
ARID5AAT-rich interaction domain 5A. (555 aa)
GLYR1PWWP domain-containing protein. (553 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ENSOCUP00000043169Uncharacterized protein. (414 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
ENSOCUP00000040876PWWP domain-containing protein. (559 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1478 aa)
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (327 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
ENSOCUP00000033150Uncharacterized protein. (70 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (614 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1446 aa)
G1TVW2_RABITUncharacterized protein. (396 aa)
SF3B1SF3b1 domain-containing protein. (1120 aa)
ISL1ISL LIM homeobox 1. (349 aa)
BRD7Bromodomain containing 7. (632 aa)
ARRB1Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] (408 aa)
FOXP3Forkhead box P3. (455 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
AUTS2Activator of transcription and developmental regulator AUTS2. (803 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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