STRINGSTRING
PPP1R12A PPP1R12A GBA GBA GNA12 GNA12 PPP2R5D PPP2R5D PDGFRB PDGFRB SYMPK SYMPK PPP1R14D PPP1R14D PINK1 PINK1 G1SV95_RABIT G1SV95_RABIT LRRC46 LRRC46 CDH5 CDH5 ITGA1 ITGA1 PTPRC PTPRC AGTR2 AGTR2 LRRC43 LRRC43 PAWR PAWR CDCA2 CDCA2 TMEM130 TMEM130 SMPD1 SMPD1 JAK2 JAK2 NSMF NSMF G1TEF9_RABIT G1TEF9_RABIT SLC39A10 SLC39A10 PPP1R16B PPP1R16B PPIA PPIA PRKCD PRKCD DLC1 DLC1 CAMTA1 CAMTA1 LOC103345451 LOC103345451 MAGI2 MAGI2 PPP2R5A PPP2R5A ENSOCUP00000037329 ENSOCUP00000037329 CD300A CD300A CNEP1R1 CNEP1R1 PPP1R7 PPP1R7 ENSOCUP00000041840 ENSOCUP00000041840 VRK3 VRK3 AMBRA1 AMBRA1 ENSOCUP00000044284 ENSOCUP00000044284 PTPA PTPA ANKLE2 ANKLE2 ENSOCUP00000045925 ENSOCUP00000045925 PIN1 PIN1 SPPL3 SPPL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R12AProtein phosphatase 1 regulatory subunit. (1085 aa)
GBAGlucosylceramidase. (536 aa)
GNA12G protein subunit alpha 12. (457 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family. (553 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa)
SYMPKSymplekin. (990 aa)
PPP1R14DUncharacterized protein. (146 aa)
PINK1PTEN induced kinase 1. (569 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
LRRC46Leucine rich repeat containing 46. (322 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (974 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1178 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
AGTR2Angiotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LRRC43Leucine rich repeat containing 43. (624 aa)
PAWRPro-apoptotic WT1 regulator. (339 aa)
CDCA2Cell division cycle associated 2. (1012 aa)
TMEM130Transmembrane protein 130. (486 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (469 aa)
G1TEF9_RABITPP1c_bdg domain-containing protein. (587 aa)
SLC39A10Solute carrier family 39 member 10. (832 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (421 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (164 aa)
PRKCDUncharacterized protein. (807 aa)
DLC1DLC1 Rho GTPase activating protein. (1590 aa)
CAMTA1Calmodulin binding transcription activator 1. (1616 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1449 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (495 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
CD300AIg-like domain-containing protein. (384 aa)
CNEP1R1CTD nuclear envelope phosphatase 1 regulatory subunit 1. (208 aa)
PPP1R7Uncharacterized protein. (631 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
VRK3VRK serine/threonine kinase 3. (479 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1300 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyr [...] (597 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (883 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (224 aa)
SPPL3Signal peptide peptidase like 3. (456 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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