7 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	ACVR1C	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
	ACVR1B	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (474 aa)
	SMAD3	SMAD family member 3. (230 aa)
	TDGF1	EGF-like domain-containing protein. (259 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (249 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVR1B	ACVR1C	ENSOCUP00000015408	ENSOCUP00000007947	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.977
ACVR1B	NODAL	ENSOCUP00000015408	ENSOCUP00000007498	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Nodal growth differentiation factor.	0.971
ACVR1B	SMAD2	ENSOCUP00000015408	ENSOCUP00000009717	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.986
ACVR1B	SMAD3	ENSOCUP00000015408	ENSOCUP00000027151	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	SMAD family member 3.	0.979
ACVR1B	TDGF1	ENSOCUP00000015408	ENSOCUP00000042810	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	EGF-like domain-containing protein.	0.763
ACVR1C	ACVR1B	ENSOCUP00000007947	ENSOCUP00000015408	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.977
ACVR1C	NODAL	ENSOCUP00000007947	ENSOCUP00000007498	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Nodal growth differentiation factor.	0.959
ACVR1C	SMAD2	ENSOCUP00000007947	ENSOCUP00000009717	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.976
ACVR1C	SMAD3	ENSOCUP00000007947	ENSOCUP00000027151	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	SMAD family member 3.	0.966
ACVR1C	TDGF1	ENSOCUP00000007947	ENSOCUP00000042810	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	EGF-like domain-containing protein.	0.688
CITED2	SMAD2	ENSOCUP00000048008	ENSOCUP00000009717	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Mothers against decapentaplegic homolog.	0.595
NODAL	ACVR1B	ENSOCUP00000007498	ENSOCUP00000015408	Nodal growth differentiation factor.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.971
NODAL	ACVR1C	ENSOCUP00000007498	ENSOCUP00000007947	Nodal growth differentiation factor.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.959
NODAL	SMAD2	ENSOCUP00000007498	ENSOCUP00000009717	Nodal growth differentiation factor.	Mothers against decapentaplegic homolog.	0.650
NODAL	SMAD3	ENSOCUP00000007498	ENSOCUP00000027151	Nodal growth differentiation factor.	SMAD family member 3.	0.530
NODAL	TDGF1	ENSOCUP00000007498	ENSOCUP00000042810	Nodal growth differentiation factor.	EGF-like domain-containing protein.	0.821
SMAD2	ACVR1B	ENSOCUP00000009717	ENSOCUP00000015408	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.986
SMAD2	ACVR1C	ENSOCUP00000009717	ENSOCUP00000007947	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.976
SMAD2	CITED2	ENSOCUP00000009717	ENSOCUP00000048008	Mothers against decapentaplegic homolog.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	0.595
SMAD2	NODAL	ENSOCUP00000009717	ENSOCUP00000007498	Mothers against decapentaplegic homolog.	Nodal growth differentiation factor.	0.650