STRINGSTRING
LOC100356250 LOC100356250 ACVRL1 ACVRL1 TSKU TSKU F10 F10 F5 F5 HRG HRG G1U7R8_RABIT G1U7R8_RABIT GATA1 GATA1 CHMP1A CHMP1A TMEFF2 TMEFF2 CHMP4C CHMP4C SLC11A1 SLC11A1 PPARD PPARD F3 F3 ITGB6 ITGB6 ITGA2 ITGA2 SFTA3 SFTA3 TGFBR2 TGFBR2 ENSOCUP00000030584 ENSOCUP00000030584 COL5A1 COL5A1 LOC103345451 LOC103345451 FGG FGG GRHL3 GRHL3 SDC4 SDC4 CD34 CD34 KNG1 KNG1 ITGB3 ITGB3 FGFR2 FGFR2 ENSOCUP00000034349 ENSOCUP00000034349 SLC4A1 SLC4A1 PRSS56 PRSS56 NOTCH2 NOTCH2 ELK3 ELK3 LOC103349708 LOC103349708 PAK1 PAK1 ENSOCUP00000037329 ENSOCUP00000037329 HBEGF HBEGF PLEK PLEK ENSOCUP00000038708 ENSOCUP00000038708 PAPSS2 PAPSS2 GHRHR GHRHR CHMP5 CHMP5 ARHGAP24 ARHGAP24 ENSOCUP00000040428 ENSOCUP00000040428 ERBB2 ERBB2 ADAM17 ADAM17 PLET1 PLET1 PPARA PPARA FZD6 FZD6 SERPIND1 SERPIND1 CARMIL2 CARMIL2 IL1A IL1A SYT11 SYT11 HIF1A HIF1A PF4 PF4 NF1 NF1 FGF10 FGF10 G1SV95_RABIT G1SV95_RABIT FGFR1OP2 FGFR1OP2 MMP12 MMP12 TFPI TFPI GNA13 GNA13 CX3CL1 CX3CL1 F11 F11 TREML1 TREML1 ENG ENG HNF4A HNF4A FER1L5 FER1L5 HPS4 HPS4 TYRO3 TYRO3 MMRN1 MMRN1 PDPN PDPN ANXA6 ANXA6 TGFB2 TGFB2 F9 F9 KDR KDR PIK3CB PIK3CB C1GALT1C1 C1GALT1C1 SERPINE2 SERPINE2 MYH9 MYH9 SMAD4 SMAD4 CD40LG CD40LG CCN1 CCN1 STXBP3 STXBP3 SRF SRF SERPINC1 SERPINC1 PTK7 PTK7 F12 F12 F2RL1 F2RL1 VKORC1 VKORC1 TLR4 TLR4 GATA4 GATA4 NDNF NDNF PDGFRB PDGFRB SLC7A11 SLC7A11 HPS1 HPS1 CTSG CTSG GP1BA GP1BA F13B F13B FLNA FLNA CCL20 CCL20 FKBP10 FKBP10 FGF2 FGF2 WNT5A WNT5A PDGFRA PDGFRA ANO6 ANO6 SERPING1 SERPING1 PROC PROC ENSOCUP00000041840 ENSOCUP00000041840 CHMP1B CHMP1B ENSOCUP00000042043 ENSOCUP00000042043 LRRC1 LRRC1 F7 F7 CHMP2B CHMP2B PEAR1 PEAR1 DTNBP1 DTNBP1 CDH3 CDH3 MPL MPL PLPP3 PLPP3 LOX LOX ENSOCUP00000044284 ENSOCUP00000044284 MYOF MYOF DCBLD2 DCBLD2 AP3B1 AP3B1 ENSOCUP00000045925 ENSOCUP00000045925 HPS5 HPS5 ENSOCUP00000047104 ENSOCUP00000047104 GPR4 GPR4 CD44 CD44 ENSOCUP00000048211 ENSOCUP00000048211 ENSOCUP00000048771 ENSOCUP00000048771 MACF1 MACF1 ADAMTS13 ADAMTS13 C12H6orf89 C12H6orf89 F8 F8 GNAS GNAS MPIG6B MPIG6B DDR1 DDR1 LOC100346856 LOC100346856 SYT7 SYT7 ALOX15 ALOX15 GP9 GP9 STXBP1 STXBP1 PROS1 PROS1 G1TQ45_RABIT G1TQ45_RABIT ADRA2B ADRA2B MYOZ1 MYOZ1 G1TQZ8_RABIT G1TQZ8_RABIT ODAM ODAM F2R F2R INS INS LOC100348967 LOC100348967 ARHGEF19 ARHGEF19 TOR1A TOR1A SDC1 SDC1 IGF1 IGF1 PPIA PPIA CAV3 CAV3 P2RY8 P2RY8 MRTFA MRTFA MCAM MCAM B7NZQ1_RABIT B7NZQ1_RABIT P2RX1 P2RX1 DYSF DYSF CCDC70 CCDC70 G1U4T0_RABIT G1U4T0_RABIT P2RY1 P2RY1 MERTK MERTK TIMP1 TIMP1 HPSE HPSE FBLN1 FBLN1 SYTL4 SYTL4 FGB FGB FGA FGA SMAD2 SMAD2 KLKB1 KLKB1 TGFB3 TGFB3 CLDN1 CLDN1 PPL PPL ENTPD1 ENTPD1 ENPP4 ENPP4 UBASH3B UBASH3B DSP DSP RHOA RHOA ITGA5 ITGA5 IL33 IL33 FGF1 FGF1 DST DST ANXA8 ANXA8 RAP2B RAP2B SERPINB2 SERPINB2 EVPL EVPL COL3A1 COL3A1 EXT1 EXT1 PDCD10 PDCD10 TRIM72 TRIM72 MAP3K5 MAP3K5 CHMP7 CHMP7 SMPD1 SMPD1 CDKN1A CDKN1A EPB41L4B EPB41L4B PROCR PROCR CHMP2A CHMP2A AXL AXL SHH SHH JAML JAML ARHGAP35 ARHGAP35 BLOC1S6 BLOC1S6 ANXA5 ANXA5 CPB2 CPB2 LOC100346323 LOC100346323 AJUBA AJUBA HMOX1 HMOX1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC100356250Uncharacterized protein. (292 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (327 aa)
TSKUTsukushi, small leucine rich proteoglycan. (399 aa)
F10Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family. (560 aa)
F5Coagulation factor V. (2102 aa)
HRGHistidine-rich glycoprotein; Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Inhibits rosette formation. Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as hepari [...] (572 aa)
G1U7R8_RABITUncharacterized protein. (311 aa)
GATA1GATA binding protein 1. (413 aa)
CHMP1ACharged multivesicular body protein 1A. (193 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (382 aa)
CHMP4CCharged multivesicular body protein 4C. (260 aa)
SLC11A1Uncharacterized protein. (552 aa)
PPARDUncharacterized protein. (420 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (397 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (787 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa)
SFTA3Surfactant associated 3. (92 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ENSOCUP00000030584Uncharacterized protein. (513 aa)
COL5A1Fibrillar collagen NC1 domain-containing protein. (383 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
FGGFibrinogen gamma chain. (450 aa)
GRHL3Grainyhead like transcription factor 3. (619 aa)
SDC4Syndecan 4. (197 aa)
CD34CD34 molecule. (415 aa)
KNG1Kininogen 1. (633 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (873 aa)
FGFR2Fibroblast growth factor receptor. (894 aa)
ENSOCUP00000034349Uncharacterized protein. (160 aa)
SLC4A1Anion exchange protein. (981 aa)
PRSS56Serine protease 56. (681 aa)
NOTCH2Notch receptor 2. (2481 aa)
ELK3ETS transcription factor ELK3. (457 aa)
LOC103349708Transglut_N domain-containing protein. (324 aa)
PAK1Non-specific serine/threonine protein kinase. (585 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
HBEGFHeparin binding EGF like growth factor. (228 aa)
PLEKPleckstrin. (350 aa)
ENSOCUP00000038708Uncharacterized protein. (167 aa)
PAPSS2Uncharacterized protein. (766 aa)
GHRHRUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (524 aa)
CHMP5Charged multivesicular body protein 5. (306 aa)
ARHGAP24Rho GTPase activating protein 24. (748 aa)
ENSOCUP00000040428Uncharacterized protein. (86 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
PLET1Uncharacterized protein. (212 aa)
PPARAPeroxisome proliferator activated receptor alpha. (503 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
SERPIND1Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). (480 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1445 aa)
IL1AInterleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (267 aa)
SYT11Synaptotagmin 11. (440 aa)
HIF1AUncharacterized protein. (851 aa)
PF4Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (105 aa)
NF1Neurofibromin 1. (2841 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
FGFR1OP2FGFR1 oncogene partner 2. (253 aa)
MMP12Macrophage metalloelastase; May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). Belongs to the peptidase M10A family. (464 aa)
TFPITissue factor pathway inhibitor; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. (300 aa)
GNA13G protein subunit alpha 13. (377 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (404 aa)
F11Uncharacterized protein; Belongs to the peptidase S1 family. (624 aa)
TREML1Ig-like domain-containing protein. (452 aa)
ENGEndoglin. (758 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (468 aa)
FER1L5Fer-1 like family member 5. (2028 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (678 aa)
TYRO3TYRO3 protein tyrosine kinase. (860 aa)
MMRN1Multimerin 1. (1211 aa)
PDPNUncharacterized protein. (164 aa)
ANXA6Annexin. (913 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
F9Coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. (462 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
C1GALT1C1C1GALT1 specific chaperone 1. (322 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1920 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
CCN1Cellular communication network factor 1. (386 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (556 aa)
SRFSerum response factor. (685 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (465 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (978 aa)
F12Coagulation factor XII. (617 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (162 aa)
TLR4TIR domain-containing protein; Belongs to the Toll-like receptor family. (839 aa)
GATA4GATA binding protein 4. (444 aa)
NDNFNeuron derived neurotrophic factor. (643 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa)
SLC7A11Solute carrier family 7 member 11. (502 aa)
HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (703 aa)
CTSGCathepsin G. (250 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (615 aa)
F13BCoagulation factor XIII B chain. (660 aa)
FLNAUncharacterized protein. (2617 aa)
CCL20C-C motif chemokine. (96 aa)
FKBP10Peptidylprolyl isomerase. (448 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa)
WNT5AProtein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa)
PDGFRAProtein kinase domain-containing protein. (773 aa)
ANO6Anoctamin. (1003 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (521 aa)
PROCVitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. (498 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
CHMP1BCharged multivesicular body protein 1B. (209 aa)
ENSOCUP00000042043Ig-like domain-containing protein. (212 aa)
LRRC1Leucine rich repeat containing 1. (458 aa)
F7Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). (602 aa)
CHMP2BCharged multivesicular body protein 2B. (221 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1024 aa)
DTNBP1Uncharacterized protein. (336 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (1102 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
PLPP3acidPPc domain-containing protein. (331 aa)
LOXLysyl oxidase. (419 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
MYOFMyoferlin. (2081 aa)
DCBLD2Discoidin, CUB and LCCL domain containing 2. (760 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1187 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
HPS5Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1131 aa)
ENSOCUP00000047104Calponin-homology (CH) domain-containing protein. (267 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (361 aa)
CD44CD44 molecule (Indian blood group). (761 aa)
ENSOCUP00000048211Uncharacterized protein. (2099 aa)
ENSOCUP00000048771Uncharacterized protein. (318 aa)
MACF1Microtubule actin crosslinking factor 1. (7577 aa)
ADAMTS13ACR domain-containing protein. (428 aa)
C12H6orf89Uncharacterized protein. (311 aa)
F8Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. (2336 aa)
GNASGNAS complex locus. (977 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (288 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (1040 aa)
LOC100346856Uncharacterized protein. (316 aa)
SYT7Synaptotagmin 7. (523 aa)
ALOX15Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (674 aa)
GP9Glycoprotein IX platelet. (164 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (590 aa)
PROS1Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. (695 aa)
G1TQ45_RABITUncharacterized protein. (193 aa)
ADRA2BAlpha-2B adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. (411 aa)
MYOZ1Uncharacterized protein. (310 aa)
G1TQZ8_RABITUncharacterized protein. (193 aa)
ODAMOdontogenic, ameloblast associated. (279 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (460 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa)
LOC100348967Uncharacterized protein. (316 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (679 aa)
TOR1ATorsin family 1 member A. (384 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (401 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (164 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
P2RY8P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (382 aa)
MRTFAMyocardin related transcription factor A. (649 aa)
MCAMMelanoma cell adhesion molecule. (578 aa)
B7NZQ1_RABITFLNA protein (Predicted). (780 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
DYSFDysferlin. (2121 aa)
CCDC70Coiled-coil domain containing 70. (233 aa)
G1U4T0_RABITUncharacterized protein. (116 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
MERTKMER proto-oncogene, tyrosine kinase. (968 aa)
TIMP1Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (256 aa)
HPSEHeparanase. (681 aa)
FBLN1Fibulin 1. (457 aa)
SYTL4Synaptotagmin like 4. (671 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (492 aa)
FGAFibrinogen alpha chain. (813 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (629 aa)
TGFB3Transforming growth factor beta 3. (458 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
PPLPeriplakin. (1695 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (509 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (505 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
DSPDesmoplakin. (2814 aa)
RHOARas homolog family member A. (193 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa)
IL33Uncharacterized protein. (142 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
DSTDystonin. (5538 aa)
ANXA8Annexin A8; This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade; Belongs to the annexin family. (327 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
SERPINB2Serine proteinase inhibitor, clade B, member 2 (Predicted); Belongs to the serpin family. (417 aa)
EVPLSH3 domain-containing protein. (1884 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PDCD10Programmed cell death 10. (212 aa)
TRIM72Tripartite motif-containing protein 72; Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)- depen [...] (477 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1316 aa)
CHMP7Charged multivesicular body protein 7. (475 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
CDKN1AUncharacterized protein. (231 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (811 aa)
PROCRProtein C receptor. (240 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
AXLAXL receptor tyrosine kinase. (625 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa)
JAMLUncharacterized protein. (388 aa)
ARHGAP35Rho GTPase activating protein 35. (1415 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (174 aa)
ANXA5Annexin. (321 aa)
CPB2Carboxypeptidase B2. (424 aa)
LOC100346323Uncharacterized protein. (240 aa)
AJUBAUncharacterized protein. (122 aa)
HMOX1Heme oxygenase 1. (288 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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