STRINGSTRING
UGT8 UGT8 LPAR1 LPAR1 PARD3 PARD3 MPP5 MPP5 BCAS1 BCAS1 ILK ILK MBP MBP SLC8A3 SLC8A3 ENSOCUP00000045925 ENSOCUP00000045925 CD9 CD9 NDRG1 NDRG1 KEL KEL ENSOCUP00000044284 ENSOCUP00000044284 EPB41L3 EPB41L3 JAM3 JAM3 B4GALT5 B4GALT5 ENSOCUP00000041840 ENSOCUP00000041840 TNFRSF21 TNFRSF21 MYRF MYRF SIRT2 SIRT2 PLLP PLLP MAL MAL TSC1 TSC1 SLC25A46 SLC25A46 ENSOCUP00000037329 ENSOCUP00000037329 NCMAP NCMAP ANK2 ANK2 NAB2 NAB2 NRG1 NRG1 MPDZ MPDZ LGI4 LGI4 SERINC5 SERINC5 B4GALT6 B4GALT6 LOC103345451 LOC103345451 FA2H FA2H ITGB4 ITGB4 FIG4 FIG4 ERCC2 ERCC2 CNTNAP1 CNTNAP1 U3KP67_RABIT U3KP67_RABIT DHH DHH NTF3 NTF3 PRX PRX GJC3-2 GJC3-2 AMIGO1 AMIGO1 AMIGO2 AMIGO2 MAG MAG SH3TC2 SH3TC2 EIF2B4 EIF2B4 REG1A REG1A DEGS1 DEGS1 ACER3 ACER3 G1TTB9_RABIT G1TTB9_RABIT SOD1 SOD1 MARVELD1 MARVELD1 ABCD1 ABCD1 ABCD2 ABCD2 MYOC MYOC ADAM22 ADAM22 CNTN2 CNTN2 NFASC NFASC PLP1 PLP1 CMTM8 CMTM8 MTMR2 MTMR2 NCSTN NCSTN MPZ MPZ EGR2 EGR2 ATRN ATRN ORMDL1 ORMDL1 GJC3 GJC3 G1T1S8_RABIT G1T1S8_RABIT DICER1 DICER1 ERBB2 ERBB2 EIF2B2 EIF2B2 NTRK2 NTRK2 ORMDL3 ORMDL3 GAL3ST1 GAL3ST1 CNTN1 CNTN1 GALC GALC HEXA HEXA PTEN PTEN NF1 NF1 NAB1 NAB1 G1SV95_RABIT G1SV95_RABIT FAM126A FAM126A XK XK CLU CLU ASPA ASPA GNPAT GNPAT HEXB HEXB MALL MALL TENM4 TENM4 EIF2B5 EIF2B5 QKI QKI DAG1 DAG1 TPPP TPPP PIKFYVE PIKFYVE ADGRG6 ADGRG6 TSPAN2 TSPAN2 AKT2 AKT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (574 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
PARD3Par-3 family cell polarity regulator. (1340 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (698 aa)
BCAS1Breast carcinoma amplified sequence 1. (650 aa)
ILKIntegrin linked kinase. (510 aa)
MBPMyelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity); Belongs to the myelin basic protein family. (417 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (958 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
CD9Tetraspanin. (385 aa)
NDRG1N-myc downstream regulated 1. (438 aa)
KELKell metallo-endopeptidase (Kell blood group). (732 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1447 aa)
JAM3Junctional adhesion molecule 3. (405 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (369 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
MYRFMyelin regulatory factor. (1063 aa)
SIRT2Sirtuin 2. (509 aa)
PLLPPlasmolipin. (231 aa)
MALMal, T cell differentiation protein. (157 aa)
TSC1Uncharacterized protein. (988 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (430 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
NCMAPUncharacterized protein. (224 aa)
ANK2Ankyrin 2. (3805 aa)
NAB2NGFI-A binding protein 2. (545 aa)
NRG1Neuregulin 1. (720 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2107 aa)
LGI4Leucine rich repeat LGI family member 4. (694 aa)
SERINC5Serine incorporator 5. (511 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (371 aa)
ITGB4Integrin beta. (1708 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (907 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (805 aa)
CNTNAP1Contactin associated protein 1. (1450 aa)
U3KP67_RABITUncharacterized protein. (234 aa)
DHHDesert hedgehog signaling molecule. (388 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
PRXPeriaxin. (1286 aa)
GJC3-2Uncharacterized protein. (254 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
AMIGO2Ig-like domain-containing protein. (810 aa)
MAGUncharacterized protein. (58 aa)
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1295 aa)
EIF2B4Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family. (522 aa)
REG1ARegenerating family member 1 alpha. (182 aa)
DEGS1FA_desaturase domain-containing protein. (287 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
G1TTB9_RABITUncharacterized protein. (200 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
MARVELD1MARVEL domain containing 1. (173 aa)
ABCD1ATP binding cassette subfamily D member 1. (741 aa)
ABCD2ATP binding cassette subfamily D member 2. (668 aa)
MYOCMyocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (490 aa)
ADAM22ADAM metallopeptidase domain 22. (866 aa)
CNTN2Contactin 2. (1040 aa)
NFASCNeurofascin. (1331 aa)
PLP1Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. (357 aa)
CMTM8CKLF like MARVEL transmembrane domain containing 8. (173 aa)
MTMR2Myotubularin related protein 2. (643 aa)
NCSTNNicastrin. (667 aa)
MPZMyelin protein zero. (299 aa)
EGR2Early growth response 2. (549 aa)
ATRNAttractin. (1426 aa)
ORMDL1Uncharacterized protein. (308 aa)
GJC3Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (275 aa)
G1T1S8_RABITFA_desaturase domain-containing protein. (316 aa)
DICER1Uncharacterized protein. (821 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
EIF2B2Translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family. (397 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
GAL3ST1Uncharacterized protein. (598 aa)
CNTN1Contactin 1. (1018 aa)
GALCGalactosylceramidase. (764 aa)
HEXABeta-hexosaminidase. (529 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NF1Neurofibromin 1. (2841 aa)
NAB1NGFI-A binding protein 1. (486 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
FAM126AFamily with sequence similarity 126 member A. (521 aa)
XKXK-related protein. (444 aa)
CLUClusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (518 aa)
ASPAAspartoacylase. (344 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (679 aa)
HEXBBeta-hexosaminidase. (532 aa)
MALLMal, T cell differentiation protein like. (151 aa)
TENM4Teneurin transmembrane protein 4. (2706 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. (729 aa)
QKIQKI, KH domain containing RNA binding. (345 aa)
DAG1Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (895 aa)
TPPPTubulin polymerization promoting protein. (171 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2074 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1250 aa)
TSPAN2Tetraspanin. (220 aa)
AKT2AKT serine/threonine kinase 2. (442 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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