STRINGSTRING
CDO1 CDO1 INPPL1 INPPL1 AKT2 AKT2 SLC26A6 SLC26A6 NR4A3 NR4A3 SRD5A2 SRD5A2 EDNRA EDNRA SOCS2 SOCS2 TSHR TSHR SMARCC1 SMARCC1 G1SGL1_RABIT G1SGL1_RABIT PDPK1 PDPK1 ADCY8 ADCY8 VPS13C VPS13C PCK2 PCK2 GRB14 GRB14 STXBP3 STXBP3 LRP6 LRP6 LYN LYN LPIN1 LPIN1 SCAP SCAP SLC30A10 SLC30A10 EIF4EBP2 EIF4EBP2 AGTRAP AGTRAP FBN1 FBN1 SLC25A33 SLC25A33 TRPV4 TRPV4 GH1 GH1 GIP GIP BTG2 BTG2 SOGA1 SOGA1 EIF2B5 EIF2B5 RPS6KB1 RPS6KB1 ERRFI1 ERRFI1 RAB15 RAB15 CDC6 CDC6 STAT5B STAT5B INHBB INHBB PIK3R1 PIK3R1 IL18 IL18 CREB1 CREB1 LTA4H LTA4H NCOA5 NCOA5 LOC100344298 LOC100344298 HMGCS2 HMGCS2 G1SQ55_RABIT G1SQ55_RABIT PHEX PHEX JAK1 JAK1 NUDC NUDC BRIP1 BRIP1 APPL1 APPL1 XBP1 XBP1 IRS1 IRS1 GHSR GHSR MYO5A MYO5A PDE3B PDE3B NR5A1 NR5A1 STAT6 STAT6 EEF2K EEF2K SLC2A8 SLC2A8 ANKRD26 ANKRD26 EGR1 EGR1 G1SV95_RABIT G1SV95_RABIT PTPN1 PTPN1 ACVR1C ACVR1C SRSF5 SRSF5 PPARA PPARA LPIN2 LPIN2 AHCYL1 AHCYL1 SRSF6 SRSF6 HADHA HADHA ADM ADM VAMP2 VAMP2 GJB2 GJB2 LEP LEP EIF6 EIF6 INSRR INSRR CYFIP1 CYFIP1 IRS4 IRS4 STAT3 STAT3 DDR2 DDR2 NR4A1 NR4A1 AGRP AGRP EPRS1 EPRS1 PCSK1 PCSK1 AGTR2 AGTR2 LPIN3 LPIN3 CDK4 CDK4 KBTBD2 KBTBD2 UCP2 UCP2 POU4F2 POU4F2 IGFBP1 IGFBP1 MTOR MTOR EDN1 EDN1 RPE65 RPE65 EGR2 EGR2 INSIG1 INSIG1 SORT1 SORT1 CDKN1B CDKN1B ABCC8 ABCC8 LOC100345250 LOC100345250 FOXO1 FOXO1 MAX MAX CAV2 CAV2 CAV1 CAV1 PRKCI PRKCI IGF1R IGF1R SESN2 SESN2 PKLR PKLR GRB10 GRB10 COL3A1 COL3A1 DNAI1 DNAI1 BCAR3 BCAR3 SLC24A4 SLC24A4 APC APC TGFBR3 TGFBR3 CYP1B1 CYP1B1 SHC1 SHC1 EREG EREG AREG AREG G1TBF0_RABIT G1TBF0_RABIT WDTC1 WDTC1 PHIP PHIP RAP1GDS1 RAP1GDS1 JAK2 JAK2 GNRHR GNRHR SRD5A1 SRD5A1 PDK4 PDK4 PARP1 PARP1 CAMK2A CAMK2A PCK1 PCK1 DENND4C DENND4C G1THC3_RABIT G1THC3_RABIT CRY2 CRY2 NEFL NEFL SLC29A2 SLC29A2 GPER1 GPER1 MGARP MGARP G1TLX8_RABIT G1TLX8_RABIT RANGAP1 RANGAP1 CAPN10 CAPN10 PRLH PRLH EPM2AIP1 EPM2AIP1 RETN RETN KL KL G1TTM1_RABIT G1TTM1_RABIT INS INS ADIPOQ ADIPOQ OTOP1 OTOP1 REG1A REG1A FOS FOS PTPRA PTPRA BMP7 BMP7 ROCK2 ROCK2 YWHAG YWHAG MC4R MC4R TRARG1 TRARG1 RAB12 RAB12 SIRT1 SIRT1 GSK3A GSK3A C2CD5 C2CD5 NFKB1 NFKB1 IGFBP5 IGFBP5 STAT5A STAT5A ZNF106 ZNF106 WNT1 WNT1 TLDC1 TLDC1 G1U9D6_RABIT G1U9D6_RABIT RAB10 RAB10 NFE2L2 NFE2L2 U3KP67_RABIT U3KP67_RABIT LHCGR LHCGR ASS1 ASS1 PFKFB1 PFKFB1 UCP3 UCP3 AGTR1 AGTR1 CPEB1 CPEB1 PRKCD PRKCD CITED1 CITED1 SLC27A4 SLC27A4 TBC1D4 TBC1D4 OTC OTC PTK2 PTK2 LOC100339305 LOC100339305 CRHBP CRHBP INPP5K INPP5K STAT4 STAT4 MGRA MGRA STXBP4 STXBP4 LOC103345451 LOC103345451 HSF1 HSF1 GCK GCK CA2 CA2 ITGB3 ITGB3 GHR GHR GPLD1 GPLD1 ENSOCUP00000033961 ENSOCUP00000033961 GOT1 GOT1 SORBS1 SORBS1 GSK3B GSK3B IGFBP2 IGFBP2 SLC2A4 SLC2A4 CRHR1 CRHR1 ENSOCUP00000034710 ENSOCUP00000034710 RHOQ RHOQ CYBB CYBB FER FER TYK2 TYK2 LOC100357982 LOC100357982 PLCB1 PLCB1 CSRP3 CSRP3 SP1 SP1 ENSOCUP00000037329 ENSOCUP00000037329 BCAR1 BCAR1 POMC POMC PTK2-2 PTK2-2 HADH HADH TSC1 TSC1 ENSOCUP00000039433 ENSOCUP00000039433 CRHR2 CRHR2 STAT1 STAT1 ENSOCUP00000039845 ENSOCUP00000039845 GLP2R GLP2R POR POR FOXO4 FOXO4 STAT2 STAT2 NR4A2 NR4A2 ADCY6 ADCY6 KHK KHK PTPN2 PTPN2 RB1 RB1 GLP1R GLP1R ENSOCUP00000041459 ENSOCUP00000041459 ENSOCUP00000041840 ENSOCUP00000041840 INSR INSR GRB2 GRB2 ENSOCUP00000042867 ENSOCUP00000042867 USF1 USF1 PPARG PPARG ENSOCUP00000043938 ENSOCUP00000043938 ENSOCUP00000044284 ENSOCUP00000044284 ENSOCUP00000044310 ENSOCUP00000044310 GCLC GCLC ENSOCUP00000045925 ENSOCUP00000045925 MAP1B MAP1B SESN3 SESN3 PCSK9 PCSK9 SYAP1 SYAP1 CRY1 CRY1 CPEB2 CPEB2 SRSF4 SRSF4 LOC103349690 LOC103349690 REG3G REG3G ACTN2 ACTN2 RAB13 RAB13 CPS1 CPS1 ENPP1 ENPP1 TRIM16 TRIM16 ENSOCUP00000049162 ENSOCUP00000049162
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CDO1Cysteine dioxygenase. (200 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1362 aa)
AKT2AKT serine/threonine kinase 2. (442 aa)
SLC26A6Solute carrier family 26 member 6. (739 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (636 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SOCS2Suppressor of cytokine signaling 2. (307 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1011 aa)
G1SGL1_RABITANK_REP_REGION domain-containing protein. (312 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3693 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (556 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
LYNTyrosine-protein kinase. (636 aa)
LPIN1Lipin 1. (1106 aa)
SCAPSREBF chaperone. (1279 aa)
SLC30A10Solute carrier family 30 member 10. (479 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
AGTRAPAngiotensin II receptor associated protein. (159 aa)
FBN1Fibrillin 1. (2831 aa)
SLC25A33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (302 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (679 aa)
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (216 aa)
GIPGastric inhibitory polypeptide. (153 aa)
BTG2BTG anti-proliferation factor 2. (238 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1006 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. (729 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1; Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTO [...] (490 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (459 aa)
RAB15RAB15, member RAS oncogene family. (165 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
INHBBInhibin subunit beta B. (302 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
IL18Uncharacterized protein. (408 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
LOC100344298C-type lectin domain-containing protein. (175 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (534 aa)
G1SQ55_RABITOp_neuropeptide domain-containing protein. (88 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
JAK1Tyrosine-protein kinase. (1151 aa)
NUDCNuclear distribution C, dynein complex regulator. (332 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1212 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
XBP1X-box binding protein 1. (208 aa)
IRS1Insulin receptor substrate 1. (1220 aa)
GHSRGrowth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). (366 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2013 aa)
PDE3BPhosphodiesterase. (1117 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa)
ANKRD26Ankyrin repeat domain 26. (1661 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (700 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
PTPN1Protein tyrosine phosphatase non-receptor type 1. (495 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SRSF5Serine and arginine rich splicing factor 5. (276 aa)
PPARAPeroxisome proliferator activated receptor alpha. (503 aa)
LPIN2Lipin 2. (935 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
SRSF6Serine/arginine-rich-splicing factor 6. (215 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (797 aa)
ADMAdrenomedullin. (187 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (226 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
INSRRTyrosine-protein kinase receptor. (1320 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1272 aa)
IRS4Insulin receptor substrate 4. (1176 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (848 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (784 aa)
AGRPAgouti related neuropeptide. (132 aa)
EPRS1Glutamyl-prolyl-tRNA synthetase. (1447 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1. (751 aa)
AGTR2Angiotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LPIN3Lipin 3. (871 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (392 aa)
KBTBD2Kelch repeat and BTB domain containing 2. (623 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
POU4F2POU domain protein. (392 aa)
IGFBP1Insulin like growth factor binding protein 1. (270 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (202 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
EGR2Early growth response 2. (549 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (292 aa)
SORT1Sortilin. (800 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ABCC8Uncharacterized protein. (1086 aa)
LOC100345250Uncharacterized protein. (461 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
MAXMYC associated factor X. (160 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
IGF1RTyrosine-protein kinase receptor. (1464 aa)
SESN2Sestrin 2. (480 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
GRB10Growth factor receptor bound protein 10. (550 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
DNAI1Dynein axonemal intermediate chain 1. (704 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (827 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (613 aa)
APCAPC regulator of WNT signaling pathway. (2871 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
SHC1SHC adaptor protein 1. (474 aa)
EREGEpiregulin. (169 aa)
AREGAmphiregulin. (275 aa)
G1TBF0_RABITANK_REP_REGION domain-containing protein. (621 aa)
WDTC1WD and tetratricopeptide repeats 1. (676 aa)
PHIPPleckstrin homology domain interacting protein. (1742 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (605 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
GNRHRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (328 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
DENND4CDENN domain containing 4C. (1958 aa)
G1THC3_RABITPNPLA domain-containing protein. (443 aa)
CRY2Cryptochrome circadian regulator 2. (615 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (548 aa)
SLC29A2Solute carrier family 29 member 2. (364 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
MGARPMitochondria localized glutamic acid rich protein. (312 aa)
G1TLX8_RABITRING-type domain-containing protein. (248 aa)
RANGAP1Ran GTPase activating protein 1. (630 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (660 aa)
PRLHProlactin releasing hormone. (87 aa)
EPM2AIP1EPM2A interacting protein 1. (599 aa)
RETNResistin. (112 aa)
KLKlotho. (1005 aa)
G1TTM1_RABITBromo domain-containing protein. (95 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa)
ADIPOQC1q domain-containing protein. (244 aa)
OTOP1Otopetrin 1. (556 aa)
REG1ARegenerating family member 1 alpha. (182 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (816 aa)
BMP7TGF_BETA_2 domain-containing protein. (170 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1131 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
MC4RMelanocortin 4 receptor. (333 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (251 aa)
RAB12RAB12, member RAS oncogene family. (238 aa)
SIRT1Sirtuin 1. (748 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa)
C2CD5C2 calcium dependent domain containing 5. (1129 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
IGFBP5Insulin like growth factor binding protein 5. (271 aa)
STAT5ASignal transducer and activator of transcription. (793 aa)
ZNF106Zinc finger protein 106. (1879 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
TLDC1TLDc domain-containing protein. (311 aa)
G1U9D6_RABITUncharacterized protein. (105 aa)
RAB10RAB10, member RAS oncogene family. (231 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (677 aa)
U3KP67_RABITUncharacterized protein. (234 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (732 aa)
ASS1Uncharacterized protein. (251 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (534 aa)
UCP3Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
AGTR1Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CPEB1RRM domain-containing protein. (653 aa)
PRKCDUncharacterized protein. (807 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (360 aa)
SLC27A4Solute carrier family 27 member 4. (736 aa)
TBC1D4TBC1 domain family member 4. (1297 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (360 aa)
PTK2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1041 aa)
LOC100339305Uncharacterized protein. (506 aa)
CRHBPCorticotropin releasing hormone binding protein. (382 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (532 aa)
STAT4Signal transducer and activator of transcription. (752 aa)
MGRAMas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. (325 aa)
STXBP4Syntaxin binding protein 4. (555 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
HSF1Heat shock transcription factor 1. (680 aa)
GCKPhosphotransferase. (246 aa)
CA2Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. (269 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (873 aa)
GHRGrowth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). (692 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (852 aa)
ENSOCUP00000033961ANK_REP_REGION domain-containing protein. (226 aa)
GOT1Aspartate aminotransferase. (442 aa)
SORBS1Sorbin and SH3 domain containing 1. (1293 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
IGFBP2IGFBP N-terminal domain-containing protein. (442 aa)
SLC2A4MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (574 aa)
CRHR1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (429 aa)
ENSOCUP00000034710Uncharacterized protein. (391 aa)
RHOQUncharacterized protein. (356 aa)
CYBBFAD-binding FR-type domain-containing protein. (570 aa)
FERTyrosine-protein kinase. (452 aa)
TYK2Non-specific protein-tyrosine kinase. (1065 aa)
LOC100357982BZIP domain-containing protein. (301 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
CSRP3Cysteine and glycine rich protein 3. (245 aa)
SP1Sp1 transcription factor. (792 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (869 aa)
POMCNPP domain-containing protein. (285 aa)
PTK2-2FERM_N_2 domain-containing protein. (121 aa)
HADHHydroxyacyl-CoA dehydrogenase. (424 aa)
TSC1Uncharacterized protein. (988 aa)
ENSOCUP00000039433Uncharacterized protein. (120 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
STAT1Signal transducer and activator of transcription. (879 aa)
ENSOCUP00000039845Uncharacterized protein. (123 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (535 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the N-terminal section; belongs to the flavodoxin family. (439 aa)
FOXO4Forkhead box O4. (503 aa)
STAT2STAT_int domain-containing protein. (205 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (609 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1204 aa)
KHKKetohexokinase. (352 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
RB1RB transcriptional corepressor 1. (943 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (488 aa)
ENSOCUP00000041459Uncharacterized protein. (98 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
INSRTyrosine-protein kinase receptor. (1377 aa)
GRB2Growth factor receptor bound protein 2. (278 aa)
ENSOCUP00000042867Uncharacterized protein. (340 aa)
USF1Upstream stimulatory factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. Regulates the expression of the surfactant protein- A (SP-A) gene. (326 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSOCUP00000043938Uncharacterized protein. (50 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ENSOCUP00000044310ANK_REP_REGION domain-containing protein. (624 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (664 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
MAP1BMicrotubule associated protein 1B. (2355 aa)
SESN3Sestrin 3. (492 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (686 aa)
SYAP1Synapse associated protein 1. (370 aa)
CRY1Cryptochrome circadian regulator 1. (613 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (698 aa)
SRSF4Serine and arginine rich splicing factor 4. (507 aa)
LOC103349690DUF3496 domain-containing protein. (645 aa)
REG3GC-type lectin domain-containing protein. (221 aa)
ACTN2Actinin alpha 2. (893 aa)
RAB13Uncharacterized protein. (237 aa)
CPS1Carbamoyl-phosphate synthase 1. (1506 aa)
ENPP1Uncharacterized protein. (908 aa)
TRIM16Uncharacterized protein. (551 aa)
ENSOCUP00000049162Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (793 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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