STRINGSTRING
S1PR1 S1PR1 LIPE LIPE G1SCK7_RABIT G1SCK7_RABIT LAMTOR1 LAMTOR1 ARID3C ARID3C UNC5A UNC5A LCP2 LCP2 SLC1A2 SLC1A2 OPRD1 OPRD1 LAMTOR3 LAMTOR3 MYO1A MYO1A SKAP1 SKAP1 LRP4 LRP4 PRNP PRNP PRSS8 PRSS8 LAMTOR5 LAMTOR5 CD36 CD36 CHRNA7 CHRNA7 PIKFYVE PIKFYVE ADCY8 ADCY8 PTCH1 PTCH1 LRP6 LRP6 LYN LYN G1SJA2_RABIT G1SJA2_RABIT SULF1 SULF1 TLR2 TLR2 DAG1 DAG1 ITGB1 ITGB1 SLC6A4 SLC6A4 RIT2 RIT2 LCK LCK TLR10 TLR10 LAMTOR4 LAMTOR4 KCND2 KCND2 CD14 CD14 CBL CBL MALL MALL CHRNA3 CHRNA3 KDR KDR HYAL2 HYAL2 CBLB CBLB STOM STOM PDPN PDPN GASK1A GASK1A TLR6 TLR6 G1SQB5_RABIT G1SQB5_RABIT STOML2 STOML2 ATP2B4 ATP2B4 TPP1 TPP1 TNF TNF HK1 HK1 UNC5B UNC5B ITLN2 ITLN2 G1SSE7_RABIT G1SSE7_RABIT IKBKB IKBKB GHSR GHSR CTNNA1 CTNNA1 THY1 THY1 IL6ST IL6ST LRRK2 LRRK2 SCN5A SCN5A STAT6 STAT6 MS4A1 MS4A1 LYPD6 LYPD6 TFPI TFPI G1SV48_RABIT G1SV48_RABIT CD2 CD2 ADCY2 ADCY2 SMPD2 SMPD2 VDAC1 VDAC1 CNTN1 CNTN1 HCK HCK HTR2A HTR2A BIRC3 BIRC3 ADAM17 ADAM17 EGFR EGFR APP APP BTK BTK HMOX1 HMOX1 TEX101 TEX101 NPHS2 NPHS2 HPSE HPSE CARD11 CARD11 ITGA1 ITGA1 G1T177_RABIT G1T177_RABIT FAIM2 FAIM2 RIPK1 RIPK1 PTPRC PTPRC TRPC4 TRPC4 PRKAR2B PRKAR2B SMURF2 SMURF2 PPT1 PPT1 LOC100341366 LOC100341366 ERLIN2 ERLIN2 KCNE1 KCNE1 CD48 CD48 MAPK1 MAPK1 MAPK3 MAPK3 G1T5Z9_RABIT G1T5Z9_RABIT BIRC2 BIRC2 TNFRSF1B TNFRSF1B ATP7A ATP7A AKAP6 AKAP6 RAP2B RAP2B ADD2 ADD2 CAV2 CAV2 CAV1 CAV1 PSEN1 PSEN1 PAG1 PAG1 IGF1R IGF1R DMD DMD PECAM1 PECAM1 FYN FYN RFTN1 RFTN1 PPP2CA PPP2CA FYB2 FYB2 EFNA5 EFNA5 SDCBP SDCBP KCNE3 KCNE3 SHH SHH JAK2 JAK2 BVES BVES ASAH2 ASAH2 FLOT1 FLOT1 CLN6 CLN6 TEK TEK CAVIN2 CAVIN2 TNR TNR LOC100346323 LOC100346323 FLOT2 FLOT2 NEU3 NEU3 TLR1 TLR1 ORAI1 ORAI1 TMBIM7P TMBIM7P MYADM MYADM KCNA5 KCNA5 CAPN2 CAPN2 STOML3 STOML3 SGCA SGCA PTK2B PTK2B KIF18A KIF18A TRADD TRADD RTN4RL1 RTN4RL1 MAL2 MAL2 CAVIN4 CAVIN4 G1TQ93_RABIT G1TQ93_RABIT SYNJ2 SYNJ2 G1TQX9_RABIT G1TQX9_RABIT CORO1C CORO1C CLIP3 CLIP3 CASP10 CASP10 F2R F2R LAMTOR2 LAMTOR2 RTN4RL2 RTN4RL2 RANGRF RANGRF SERPINH1 SERPINH1 PODXL PODXL PLPP2 PLPP2 CDH1 CDH1 MAG MAG AKAP5 AKAP5 FXYD1 FXYD1 HAS2 HAS2 RGS19 RGS19 CAV3 CAV3 SLC9A1 SLC9A1 CAVIN1 CAVIN1 P2RX1 P2RX1 MLC1 MLC1 PRKAR2A PRKAR2A LY6K LY6K BACE1 BACE1 G1U7R8_RABIT G1U7R8_RABIT NOS3 NOS3 ATP1A2 ATP1A2 SELE SELE ADRA1B ADRA1B LOC100341111 LOC100341111 NPC1 NPC1 SLC2A1 SLC2A1 PLVAP PLVAP ADRA1A ADRA1A P2RX3 P2RX3 ENSOCUP00000028861 ENSOCUP00000028861 DLC1 DLC1 PACSIN2 PACSIN2 CAVIN3 CAVIN3 ENSOCUP00000029750 ENSOCUP00000029750 FURIN FURIN EMP2 EMP2 LOC100359182 LOC100359182 TGFBR2 TGFBR2 CDH26 CDH26 LOC100355530 LOC100355530 ENSOCUP00000031376 ENSOCUP00000031376 ENSOCUP00000031395 ENSOCUP00000031395 ENSOCUP00000031759 ENSOCUP00000031759 ENSOCUP00000032008 ENSOCUP00000032008 OLR1 OLR1 SDC4 SDC4 ADTRP ADTRP CTNNB1 CTNNB1 FAS FAS SORBS1 SORBS1 SLC2A4 SLC2A4 RHOQ RHOQ SLC6A2 SLC6A2 ANK2 ANK2 ADGRG1 ADGRG1 CLN3 CLN3 TGFBR1 TGFBR1 RET RET INPP5D INPP5D CD19 CD19 CD1A CD1A STIM1 STIM1 SCARB1 SCARB1 PLPP1 PLPP1 EFNB1 EFNB1 LDHB LDHB PSEN2 PSEN2 GLIPR1L1 GLIPR1L1 ENSOCUP00000038948 ENSOCUP00000038948 GHRHR GHRHR MAL MAL PARK7 PARK7 PLLP PLLP ITGB2 ITGB2 KCNQ1 KCNQ1 SPRED1 SPRED1 LOC100348748 LOC100348748 ENSOCUP00000041637 ENSOCUP00000041637 STOML1 STOML1 DLL1 DLL1 ENSOCUP00000041843 ENSOCUP00000041843 INSR INSR TDGF1 TDGF1 ENSOCUP00000043061 ENSOCUP00000043061 RGS7 RGS7 ITLN1 ITLN1 PLPP3 PLPP3 CXADR CXADR MYOF MYOF CD55 CD55 ENSOCUP00000045141 ENSOCUP00000045141 CD8A CD8A TNFRSF1A TNFRSF1A MYO1C MYO1C LOC100356734 LOC100356734 ABCA1 ABCA1 ENSOCUP00000046835 ENSOCUP00000046835 TRPM8 TRPM8 ANGPT1 ANGPT1 SELPLG SELPLG GABBR1 GABBR1 ENSOCUP00000048927 ENSOCUP00000048927 HDAC6 HDAC6 LRP8 LRP8 ADCYAP1R1 ADCYAP1R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
S1PR1Uncharacterized protein. (356 aa)
LIPELipase E, hormone sensitive type. (1082 aa)
G1SCK7_RABITUncharacterized protein; Belongs to the cytochrome P450 family. (765 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
ARID3CAT-rich interaction domain 3C. (410 aa)
UNC5AUnc-5 netrin receptor A. (819 aa)
LCP2Lymphocyte cytosolic protein 2. (534 aa)
SLC1A2Amino acid transporter. (579 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
SKAP1Src kinase associated phosphoprotein 1. (358 aa)
LRP4LDL receptor related protein 4. (1899 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (252 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (342 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
CHRNA7Uncharacterized protein. (513 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2074 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PTCH1Patched 1. (1321 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
LYNTyrosine-protein kinase. (636 aa)
G1SJA2_RABITAnoctamin. (745 aa)
SULF1Sulfatase 1. (846 aa)
TLR2TIR domain-containing protein; Belongs to the Toll-like receptor family. (784 aa)
DAG1Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (895 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (830 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (777 aa)
RIT2Ras-like GTP binding protein. (217 aa)
LCKTyrosine-protein kinase. (637 aa)
TLR10TIR domain-containing protein; Belongs to the Toll-like receptor family. (810 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in rodent heart. Mediates the major part of the dendritic A-type current I(SA) in brain neurons (By similarity). This current is activated at membrane potentials that are below the threshold for action potentials. It regulates neuronal excitability, prolongs the latency before the first spike in a series of action potentials, regulates the frequency of repetitive action potential firing, shortens t [...] (630 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa)
CBLCbl proto-oncogene. (837 aa)
MALLMal, T cell differentiation protein like. (151 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (500 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
HYAL2Hyaluronidase. (475 aa)
CBLBCbl proto-oncogene B. (983 aa)
STOMStomatin. (284 aa)
PDPNUncharacterized protein. (164 aa)
GASK1AGolgi associated kinase 1A. (555 aa)
TLR6TIR domain-containing protein; Belongs to the Toll-like receptor family. (795 aa)
G1SQB5_RABITZP domain-containing protein. (568 aa)
STOML2Stomatin like 2. (356 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
TPP1Tripeptidyl peptidase 1. (563 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
HK1Hexokinase 1. (921 aa)
UNC5BUnc-5 netrin receptor B. (946 aa)
ITLN2Intelectin 2. (324 aa)
G1SSE7_RABITUncharacterized protein; Belongs to the peptidase C14A family. (306 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
GHSRGrowth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). (366 aa)
CTNNA1Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] (993 aa)
THY1Thy-1 cell surface antigen. (161 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
LRRK2Leucine rich repeat kinase 2. (2499 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1847 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
MS4A1Membrane spanning 4-domains A1. (298 aa)
LYPD6LY6/PLAUR domain containing 6. (165 aa)
TFPITissue factor pathway inhibitor; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. (300 aa)
G1SV48_RABITUncharacterized protein. (80 aa)
CD2CD2 molecule. (350 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1040 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (423 aa)
VDAC1Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...] (283 aa)
CNTN1Contactin 1. (1018 aa)
HCKTyrosine-protein kinase. (525 aa)
HTR2A5-hydroxytryptamine receptor 2A. (469 aa)
BIRC3Baculoviral IAP repeat containing 3. (591 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
EGFRReceptor protein-tyrosine kinase. (1193 aa)
APPGamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa)
BTKTyrosine-protein kinase. (659 aa)
HMOX1Heme oxygenase 1. (288 aa)
TEX101UPAR/Ly6 domain-containing protein. (250 aa)
NPHS2NPHS2 stomatin family member, podocin. (388 aa)
HPSEHeparanase. (681 aa)
CARD11Caspase recruitment domain family member 11. (1044 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1178 aa)
G1T177_RABITABC transporter domain-containing protein. (620 aa)
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (670 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
LOC100341366Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (345 aa)
ERLIN2ER lipid raft associated 2. (439 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (130 aa)
CD48Ig-like domain-containing protein. (291 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
MAPK3Mitogen-activated protein kinase. (381 aa)
G1T5Z9_RABITUncharacterized protein. (144 aa)
BIRC2Baculoviral IAP repeat containing 2. (601 aa)
TNFRSF1BTNF receptor superfamily member 1B. (425 aa)
ATP7AATPase copper transporting alpha. (1499 aa)
AKAP6A-kinase anchoring protein 6. (2318 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
ADD2Adducin 2. (724 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (435 aa)
IGF1RTyrosine-protein kinase receptor. (1464 aa)
DMDUncharacterized protein. (956 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (768 aa)
FYNTyrosine-protein kinase. (537 aa)
RFTN1Raftlin, lipid raft linker 1. (572 aa)
PPP2CASerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa)
FYB2FYN binding protein 2. (720 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
SDCBPSyndecan binding protein. (312 aa)
KCNE3Uncharacterized protein. (338 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
BVESBlood vessel epicardial substance. (361 aa)
ASAH2Neutral ceramidase. (759 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
CLN6CLN6 transmembrane ER protein. (311 aa)
TEKTEK receptor tyrosine kinase. (1025 aa)
CAVIN2Caveolae associated protein 2. (424 aa)
TNRTenascin R. (1359 aa)
LOC100346323Uncharacterized protein. (240 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (495 aa)
NEU3Neuraminidase 3. (498 aa)
TLR1TIR domain-containing protein; Belongs to the Toll-like receptor family. (796 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (302 aa)
TMBIM7PUncharacterized protein; Belongs to the BI1 family. (302 aa)
MYADMMyeloid associated differentiation marker. (358 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] (598 aa)
CAPN2Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. (832 aa)
STOML3Stomatin like 3. (290 aa)
SGCAAlpha-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. (440 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (892 aa)
TRADDTNFRSF1A associated via death domain. (447 aa)
RTN4RL1Reticulon 4 receptor like 1. (486 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (175 aa)
CAVIN4Caveolae associated protein 4. (355 aa)
G1TQ93_RABITUncharacterized protein. (772 aa)
SYNJ2Synaptojanin 2. (1407 aa)
G1TQX9_RABITUncharacterized protein. (475 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
CLIP3CAP-Gly domain containing linker protein 3. (498 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (469 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (460 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
RTN4RL2Uncharacterized protein. (184 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
SERPINH1SERPIN domain-containing protein; Belongs to the serpin family. (201 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] (506 aa)
PLPP2Phospholipid phosphatase 2. (269 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (884 aa)
MAGUncharacterized protein. (58 aa)
AKAP5A-kinase anchoring protein 5. (403 aa)
FXYD1Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. Belongs to the FXYD family. (119 aa)
HAS2Uncharacterized protein. (556 aa)
RGS19RGS domain-containing protein. (225 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SLC9A1Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
CAVIN1Uncharacterized protein. (142 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
MLC1Modulator of VRAC current 1. (377 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (401 aa)
LY6KUPAR/Ly6 domain-containing protein. (163 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
G1U7R8_RABITUncharacterized protein. (311 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1019 aa)
SELEE-selectin; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis; Belongs to the selectin/LECAM family. (602 aa)
ADRA1BG_PROTEIN_RECEP_F1_2 domain-containing protein. (494 aa)
LOC100341111Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (351 aa)
NPC1SSD domain-containing protein. (1289 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (512 aa)
PLVAPPlasmalemma vesicle associated protein. (437 aa)
ADRA1AAlpha-1A adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity); Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily. (466 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (410 aa)
ENSOCUP00000028861SERPIN domain-containing protein; Belongs to the serpin family. (321 aa)
DLC1DLC1 Rho GTPase activating protein. (1590 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (524 aa)
CAVIN3Caveolae associated protein 3. (267 aa)
ENSOCUP00000029750Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (907 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (666 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (259 aa)
LOC100359182Amino acid transporter. (665 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CDH26Uncharacterized protein. (444 aa)
LOC100355530SCP domain-containing protein; Belongs to the CRISP family. (294 aa)
ENSOCUP00000031376Uncharacterized protein. (95 aa)
ENSOCUP00000031395Uncharacterized protein; Belongs to the serpin family. (216 aa)
ENSOCUP00000031759Guanylate cyclase domain-containing protein. (312 aa)
ENSOCUP00000032008ABC transporter domain-containing protein. (613 aa)
OLR1Oxidized low-density lipoprotein receptor 1, soluble form; Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses includin [...] (367 aa)
SDC4Syndecan 4. (197 aa)
ADTRPAndrogen dependent TFPI regulating protein. (256 aa)
CTNNB1Catenin beta 1. (741 aa)
FASUncharacterized protein. (484 aa)
SORBS1Sorbin and SH3 domain containing 1. (1293 aa)
SLC2A4MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (574 aa)
RHOQUncharacterized protein. (356 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (653 aa)
ANK2Ankyrin 2. (3805 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (888 aa)
CLN3Battenin. (553 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (486 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (910 aa)
CD19CD19 molecule. (573 aa)
CD1AIg-like domain-containing protein. (353 aa)
STIM1Stromal interaction molecule 1. (789 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (614 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (370 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (539 aa)
GLIPR1L1SCP domain-containing protein; Belongs to the CRISP family. (277 aa)
ENSOCUP00000038948Uncharacterized protein. (118 aa)
GHRHRUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (524 aa)
MALMal, T cell differentiation protein. (157 aa)
PARK7Parkinsonism associated deglycase. (231 aa)
PLLPPlasmolipin. (231 aa)
ITGB2Integrin beta. (1009 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (695 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
LOC100348748IGv domain-containing protein. (604 aa)
ENSOCUP00000041637Uncharacterized protein. (83 aa)
STOML1PHB domain-containing protein. (701 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (754 aa)
ENSOCUP00000041843Uncharacterized protein. (172 aa)
INSRTyrosine-protein kinase receptor. (1377 aa)
TDGF1EGF-like domain-containing protein. (259 aa)
ENSOCUP00000043061Uncharacterized protein. (103 aa)
RGS7Regulator of G protein signaling 7. (508 aa)
ITLN1Intelectin 1. (389 aa)
PLPP3acidPPc domain-containing protein. (331 aa)
CXADRUncharacterized protein. (362 aa)
MYOFMyoferlin. (2081 aa)
CD55Uncharacterized protein. (430 aa)
ENSOCUP00000045141Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (273 aa)
CD8AIg-like domain-containing protein. (394 aa)
TNFRSF1ATNF receptor superfamily member 1A. (472 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1000 aa)
LOC100356734Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1283 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
ENSOCUP00000046835Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (564 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1171 aa)
ANGPT1Angiopoietin 1. (551 aa)
SELPLGUncharacterized protein. (473 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1043 aa)
ENSOCUP00000048927L-lactate dehydrogenase. (216 aa)
HDAC6Histone deacetylase 6. (1257 aa)
LRP8LDL receptor related protein 8. (1029 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (549 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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