STRINGSTRING
WNT10B WNT10B LRP3 LRP3 G1SV95_RABIT G1SV95_RABIT ENSOCUP00000037329 ENSOCUP00000037329 RUNX1T1 RUNX1T1 SIRT2 SIRT2 ENSOCUP00000041840 ENSOCUP00000041840 ENSOCUP00000044284 ENSOCUP00000044284 WWTR1 WWTR1 SIRT1 SIRT1 YAP1 YAP1 ASXL1 ASXL1 WNT1 WNT1 SMAD3 SMAD3 ANKRD26 ANKRD26 FERMT2 FERMT2 ENSOCUP00000044310 ENSOCUP00000044310 FAM57B FAM57B ENSOCUP00000045925 ENSOCUP00000045925 LOC103349690 LOC103349690 JDP2 JDP2 ENPP1 ENPP1 DDIT3 DDIT3 GATA3 GATA3 RORA RORA ENSOCUP00000033961 ENSOCUP00000033961 ENSOCUP00000036387 ENSOCUP00000036387 FLCN FLCN CCN4 CCN4 G1TBF0_RABIT G1TBF0_RABIT BBS12 BBS12 FOXO1 FOXO1 SORT1 SORT1 INSIG1 INSIG1 TRIO TRIO LOC103345451 LOC103345451 MMP11 MMP11 ADIPOQ ADIPOQ C1QL4 C1QL4 GPER1 GPER1 ZADH2 ZADH2 ARNTL ARNTL ZFPM2 ZFPM2 TRPV4 TRPV4 TRIB2 TRIB2 JAG1 JAG1 G1SGL1_RABIT G1SGL1_RABIT WNT5A WNT5A GPS2 GPS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LRP3LDL receptor related protein 3. (817 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (662 aa)
SIRT2Sirtuin 2. (509 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
WWTR1WW domain containing transcription regulator 1. (407 aa)
SIRT1Sirtuin 1. (748 aa)
YAP1Yes associated protein 1. (433 aa)
ASXL1ASXL transcriptional regulator 1. (1512 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
SMAD3SMAD family member 3. (230 aa)
ANKRD26Ankyrin repeat domain 26. (1661 aa)
FERMT2Fermitin family member 2. (696 aa)
ENSOCUP00000044310ANK_REP_REGION domain-containing protein. (624 aa)
FAM57BTLC domain-containing protein. (192 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
LOC103349690DUF3496 domain-containing protein. (645 aa)
JDP2Jun dimerization protein 2. (184 aa)
ENPP1Uncharacterized protein. (908 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
GATA3GATA binding protein 3. (444 aa)
RORARAR related orphan receptor A. (512 aa)
ENSOCUP00000033961ANK_REP_REGION domain-containing protein. (226 aa)
ENSOCUP00000036387DIX domain-containing protein. (575 aa)
FLCNFolliculin. (579 aa)
CCN4Cellular communication network factor 4. (337 aa)
G1TBF0_RABITANK_REP_REGION domain-containing protein. (621 aa)
BBS12Bardet-Biedl syndrome 12. (708 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
SORT1Sortilin. (800 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (292 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3040 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
MMP11Matrix metallopeptidase 11. (492 aa)
ADIPOQC1q domain-containing protein. (244 aa)
C1QL4Complement C1q like 4. (238 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (377 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (625 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1159 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (679 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
G1SGL1_RABITANK_REP_REGION domain-containing protein. (312 aa)
WNT5AProtein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa)
GPS2G protein pathway suppressor 2. (327 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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