STRINGSTRING
RIPK1 RIPK1 HCLS1 HCLS1 POU4F2 POU4F2 FAXDC2 FAXDC2 NCKAP1L NCKAP1L PITHD1 PITHD1 GPR68 GPR68 IL20 IL20 NEDD9 NEDD9 KLF10 KLF10 IL12B IL12B ACVR2A ACVR2A ROR2 ROR2 TAL1 TAL1 FAM210B FAM210B MPL MPL ACVR1B ACVR1B LOC100346323 LOC100346323 ENSOCUP00000045925 ENSOCUP00000045925 TNFSF11 TNFSF11 OCSTAMP OCSTAMP NINJ1 NINJ1 CASP10 CASP10 CTNNBIP1 CTNNBIP1 MED1 MED1 FOS FOS EVI2B EVI2B HOXA5 HOXA5 SMAP1 SMAP1 LEF1 LEF1 PPARGC1B PPARGC1B PPP3CA PPP3CA HAX1 HAX1 PRMT1 PRMT1 STAT5A STAT5A ETS1 ETS1 PRKCA PRKCA TRIB1 TRIB1 GATA1 GATA1 IL34 IL34 CSF1 CSF1 TRAF6 TRAF6 KAT7 KAT7 ISG15 ISG15 RAB7B RAB7B ENSOCUP00000029775 ENSOCUP00000029775 LOC103345451 LOC103345451 HSF1 HSF1 SCIN SCIN KITLG KITLG FES FES NOTCH2 NOTCH2 INPP5D INPP5D ENSOCUP00000037329 ENSOCUP00000037329 STAT1 STAT1 RB1 RB1 HIF1A HIF1A LOC100348748 LOC100348748 ENSOCUP00000041840 ENSOCUP00000041840 TESC TESC RCOR1 RCOR1 CD101 CD101 INHBA INHBA ACIN1 ACIN1 G1SGM6_RABIT G1SGM6_RABIT CALCA CALCA ANKRD54 ANKRD54 JAG1 JAG1 BRD1 BRD1 CCR1 CCR1 LIF LIF CD74 CD74 PLA2G3 PLA2G3 IL17A IL17A DCSTAMP DCSTAMP STAT5B STAT5B CREB1 CREB1 ENSOCUP00000044284 ENSOCUP00000044284 TNF TNF POU4F1 POU4F1 THPO THPO G1SSE7_RABIT G1SSE7_RABIT IL23A IL23A ABCB10 ABCB10 G1SV95_RABIT G1SV95_RABIT CSF3 CSF3 STAT3 STAT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPK1Receptor interacting serine/threonine kinase 1. (670 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (487 aa)
POU4F2POU domain protein. (392 aa)
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (309 aa)
NCKAP1LNCK associated protein 1 like. (1181 aa)
PITHD1PITH domain containing 1. (288 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
IL20Interleukin 20. (187 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (828 aa)
KLF10Kruppel like factor 10. (529 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (556 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (319 aa)
FAM210BDUF1279 domain-containing protein. (195 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (474 aa)
LOC100346323Uncharacterized protein. (240 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
OCSTAMPOsteoclast stimulatory transmembrane protein. (481 aa)
NINJ1Ninjurin 1. (152 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (469 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
EVI2BEcotropic viral integration site 2B. (455 aa)
HOXA5Homeobox A5. (381 aa)
SMAP1Small ArfGAP 1. (489 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
PPARGC1BPPARG coactivator 1 beta. (1125 aa)
PPP3CASerine/threonine-protein phosphatase. (695 aa)
HAX1Uncharacterized protein. (426 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
STAT5ASignal transducer and activator of transcription. (793 aa)
ETS1Uncharacterized protein. (533 aa)
PRKCAProtein kinase C alpha type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regul [...] (664 aa)
TRIB1Tribbles pseudokinase 1. (206 aa)
GATA1GATA binding protein 1. (413 aa)
IL34Interleukin 34. (200 aa)
CSF1Colony stimulating factor 1. (535 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (614 aa)
ISG15ISG15 ubiquitin like modifier. (164 aa)
RAB7BUncharacterized protein. (280 aa)
ENSOCUP00000029775DUF1279 domain-containing protein. (199 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
HSF1Heat shock transcription factor 1. (680 aa)
SCINScinderin. (759 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (276 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (857 aa)
NOTCH2Notch receptor 2. (2481 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (910 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
STAT1Signal transducer and activator of transcription. (879 aa)
RB1RB transcriptional corepressor 1. (943 aa)
HIF1AUncharacterized protein. (851 aa)
LOC100348748IGv domain-containing protein. (604 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
TESCTescalcin. (240 aa)
RCOR1REST corepressor 1. (386 aa)
CD101CD101 molecule. (1023 aa)
INHBAInhibin subunit beta A. (424 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1336 aa)
G1SGM6_RABITUncharacterized protein. (186 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
ANKRD54ANK_REP_REGION domain-containing protein. (180 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
BRD1Bromodomain containing 1. (1090 aa)
CCR1Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa)
LIFLIF interleukin 6 family cytokine. (203 aa)
CD74CD74 molecule. (375 aa)
PLA2G3Phospholipase A2 group III. (636 aa)
IL17AInterleukin 17A. (153 aa)
DCSTAMPDC_STAMP domain-containing protein. (283 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
POU4F1POU domain protein. (339 aa)
THPOThrombopoietin. (348 aa)
G1SSE7_RABITUncharacterized protein; Belongs to the peptidase C14A family. (306 aa)
IL23AInterleukin 23 subunit alpha. (191 aa)
ABCB10ATP binding cassette subfamily B member 10. (661 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
CSF3Colony stimulating factor 3. (204 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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