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| | LOC100357100 | CCHC-type domain-containing protein. (209 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | RCC1L | RCC1 like. (495 aa) |
| | HNRNPD | Heterogeneous nuclear ribonucleoprotein D. (286 aa) |
| | NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1030 aa) |
| | ABCF1 | ATP binding cassette subfamily F member 1. (846 aa) |
| | RBM3 | RNA binding motif protein 3. (156 aa) |
| | RMND1 | Required for meiotic nuclear division 1 homolog. (449 aa) |
| | METTL14 | Methyltransferase like 14; Belongs to the MT-A70-like family. (434 aa) |
| | SAMD4A | Sterile alpha motif domain containing 4A. (700 aa) |
| | THBS1 | Thrombospondin 1. (1171 aa) |
| | BARHL2 | BarH like homeobox 2. (387 aa) |
| | IGF2BP1 | Insulin like growth factor 2 mRNA binding protein 1. (570 aa) |
| | EIF2B5 | Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. (729 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase beta-1; Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTO [...] (490 aa) |
| | RBM4 | RNA-binding protein 4; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation [...] (365 aa) |
| | TARBP2 | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa) |
| | PKM | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcriptional activation (By similarity). Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (By similarity). (529 aa) |
| | PIWIL2 | Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (971 aa) |
| | PINK1 | PTEN induced kinase 1. (569 aa) |
| | EIF3D | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (557 aa) |
| | TENT5B | Uncharacterized protein. (428 aa) |
| | PRR16 | Proline rich 16. (304 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1651 aa) |
| | MIF4GD | MIF4G domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (490 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | KHDRBS1 | KH RNA binding domain containing, signal transduction associated 1. (443 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | UPF3A | Smg4_UPF3 domain-containing protein. (196 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | POLR2G | RNA polymerase II subunit G. (172 aa) |
| | RPL5 | 60S ribosomal protein L5. (297 aa) |
| | UPF3B | UPF3B regulator of nonsense mediated mRNA decay. (483 aa) |
| | G1SZ30_RABIT | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | METTL5 | Methyltransferase like 5. (209 aa) |
| | G1SZF4_RABIT | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | TRMT10C | tRNA methyltransferase 10C, mitochondrial RNase P subunit. (424 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa) |
| | NSUN5 | Uncharacterized protein. (101 aa) |
| | LARP1B | La ribonucleoprotein domain family member 1B. (919 aa) |
| | IMPACT | Protein IMPACT; Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 ac [...] (449 aa) |
| | BOLL | Boule homolog, RNA binding protein. (296 aa) |
| | PLD1 | Phospholipase. (1031 aa) |
| | FMR1 | Fragile X mental retardation 1. (632 aa) |
| | ELAVL1 | ELAV-like protein; Belongs to the RRM elav family. (382 aa) |
| | COA3 | Cytochrome c oxidase assembly factor 3. (106 aa) |
| | ZCCHC4 | Zinc finger CCHC-type containing 4. (511 aa) |
| | PCIF1 | PDX1 C-terminal inhibiting factor 1. (703 aa) |
| | POLDIP3 | DNA polymerase delta interacting protein 3. (420 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa) |
| | TENT4A | Terminal nucleotidyltransferase 4A. (542 aa) |
| | RPUSD4 | RNA pseudouridine synthase D4. (367 aa) |
| | UCN | Urocortin. (128 aa) |
| | DNAJC3 | DnaJ heat shock protein family (Hsp40) member C3. (497 aa) |
| | GUF1 | Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (665 aa) |
| | YTHDF2 | YTH N6-methyladenosine RNA binding protein 2. (579 aa) |
| | G1TID8_RABIT | HTH La-type RNA-binding domain-containing protein. (705 aa) |
| | SYNCRIP | Uncharacterized protein. (623 aa) |
| | CPEB3 | Cytoplasmic polyadenylation element binding protein 3. (713 aa) |
| | G1TL38_RABIT | RRM domain-containing protein. (85 aa) |
| | TRUB2 | Uncharacterized protein. (459 aa) |
| | LOC100351224 | RAP domain-containing protein. (658 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) |
| | HABP4 | HABP4_PAI-RBP1 domain-containing protein. (182 aa) |
| | G1TXL6_RABIT | PseudoU_synth_2 domain-containing protein. (434 aa) |
| | G1TXR9_RABIT | Eukaryotic translation initiation factor 5A. (114 aa) |
| | LARP4 | HTH La-type RNA-binding domain-containing protein. (725 aa) |
| | G1U0P1_RABIT | Uncharacterized protein. (209 aa) |
| | ZCCHC13 | Uncharacterized protein. (84 aa) |
| | LARP6 | La ribonucleoprotein domain family member 6. (552 aa) |
| | ENSOCUP00000023367 | annotation not available (209 aa) |
| | DHX29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1366 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | HNRNPL | Heterogeneous nuclear ribonucleoprotein L; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) |
| | POLR2D | RPOL4c domain-containing protein. (110 aa) |
| | NGRN | Neugrin, neurite outgrowth associated. (283 aa) |
| | G1U895_RABIT | RPOL4c domain-containing protein. (122 aa) |
| | JMJD4 | Jumonji domain containing 4. (560 aa) |
| | U3KMZ1_RABIT | MIF4G domain-containing protein. (342 aa) |
| | YTHDF1 | YTH N6-methyladenosine RNA binding protein 1. (652 aa) |
| | PYM1 | PYM homolog 1, exon junction complex associated factor. (204 aa) |
| | ENSOCUP00000028473 | Mab-21 domain-containing protein. (169 aa) |
| | CTIF | Cap binding complex dependent translation initiation factor. (597 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa) |
| | UHMK1 | U2AF homology motif kinase 1. (419 aa) |
| | DHX9 | DExH-box helicase 9. (1298 aa) |
| | CNBP | Uncharacterized protein. (177 aa) |
| | ENSOCUP00000030956 | Uncharacterized protein. (97 aa) |
| | CSDE1 | Cold shock domain containing E1. (851 aa) |
| | USP16 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (851 aa) |
| | ENSOCUP00000032166 | Uncharacterized protein. (108 aa) |
| | ENSOCUP00000032325 | RPOL4c domain-containing protein. (146 aa) |
| | BCL3 | BCL3 transcription coactivator. (547 aa) |
| | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. (1608 aa) |
| | ENSOCUP00000033056 | PK domain-containing protein. (265 aa) |
| | ENSOCUP00000033566 | Tudor_FRX1 domain-containing protein. (52 aa) |
| | EIF5A | Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an import [...] (154 aa) |
| | PAIP1 | MIF4G domain-containing protein. (520 aa) |
| | ENSOCUP00000033861 | Uncharacterized protein. (218 aa) |
| | ENSOCUP00000034123 | Uncharacterized protein. (421 aa) |
| | MIEF1 | Mab-21 domain-containing protein. (600 aa) |
| | LARP4B | HTH La-type RNA-binding domain-containing protein. (1726 aa) |
| | ENSOCUP00000038512 | Uncharacterized protein. (161 aa) |
| | LARP1 | La ribonucleoprotein domain family member 1. (1261 aa) |
| | MRPS27 | Mitochondrial ribosomal protein S27. (438 aa) |
| | UQCC2 | Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa) |
| | TENT4B | Terminal nucleotidyltransferase 4B. (471 aa) |
| | ENSOCUP00000040691 | Uncharacterized protein. (65 aa) |
| | FXR2 | FMR1 autosomal homolog 2. (649 aa) |
| | ENSOCUP00000041421 | CCHC-type domain-containing protein. (189 aa) |
| | FASTKD3 | FAST kinase domains 3. (706 aa) |
| | FXR1 | FMR1 autosomal homolog 1. (781 aa) |
| | METTL8 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (407 aa) |
| | NIBAN1 | Niban apoptosis regulator 1. (829 aa) |
| | DHX36 | DEAH-box helicase 36. (1468 aa) |
| | CDK5RAP1 | CDK5 regulatory subunit associated protein 1. (641 aa) |
| | ENSOCUP00000044693 | HTH La-type RNA-binding domain-containing protein. (633 aa) |
| | ENSOCUP00000044790 | RPOL4c domain-containing protein. (134 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (844 aa) |
| | RPL22L1 | Eukaryotic translation initiation factor 5A. (167 aa) |
| | ENSOCUP00000045683 | Pyruvate kinase; Belongs to the pyruvate kinase family. (144 aa) |
| | FASTKD2 | RAP domain-containing protein. (680 aa) |
| | ENSOCUP00000048602 | Ribosomal_L18_c domain-containing protein. (169 aa) |
| | YTHDF3 | YTH N6-methyladenosine RNA binding protein 3. (602 aa) |
