STRINGSTRING
CACNG7 CACNG7 SYT2 SYT2 ULK1 ULK1 CSF1 CSF1 DPYSL2 DPYSL2 G1U9D6_RABIT G1U9D6_RABIT PIK3CA PIK3CA LOC103351908 LOC103351908 SMO SMO PLAC8 PLAC8 GOLGA4 GOLGA4 HEY2 HEY2 SHTN1 SHTN1 PPARD PPARD CDKL3 CDKL3 PLXNA4 PLXNA4 MAPT MAPT MAP2 MAP2 TBX20 TBX20 TGFBR2 TGFBR2 RASAL1 RASAL1 SEMA7A SEMA7A SAV1 SAV1 MSTN MSTN ATRN ATRN TBX5 TBX5 SEMA4D SEMA4D EDN1 EDN1 CDKN1B CDKN1B AKAP6 AKAP6 SIX1 SIX1 NPPC NPPC ADNP ADNP SEMA4B SEMA4B FXN FXN IFRD1 IFRD1 HTRA2 HTRA2 PLAA PLAA RNF6 RNF6 ZP3 ZP3 ZMPSTE24 ZMPSTE24 CDKN1A CDKN1A ADRB2 ADRB2 TGFBR3 TGFBR3 EFNA5 EFNA5 COLQ COLQ WNT2 WNT2 G1TBF0_RABIT G1TBF0_RABIT SMURF1 SMURF1 BMPR1A BMPR1A WWC2 WWC2 NOL12 NOL12 BBS2 BBS2 PLS1 PLS1 SPART SPART TNR TNR MUSK MUSK G1TET4_RABIT G1TET4_RABIT LOC100346323 LOC100346323 MEGF8 MEGF8 DSPP DSPP SOX15 SOX15 NTN1 NTN1 PEX5 PEX5 SOD1 SOD1 SMAD7 SMAD7 PRLH PRLH VIL1 VIL1 G1TQX9_RABIT G1TQX9_RABIT MYOZ1 MYOZ1 GNAS GNAS LATS1 LATS1 TRIM46 TRIM46 ULK2 ULK2 WNT3A WNT3A LATS2 LATS2 TLL2 TLL2 CITED2 CITED2 LOC103349690 LOC103349690 MEF2C MEF2C RIMS2 RIMS2 ENSOCUP00000046773 ENSOCUP00000046773 FGF13 FGF13 UBE2D4 UBE2D4 MAP1B MAP1B CTDP1 CTDP1 ENSOCUP00000044310 ENSOCUP00000044310 CXADR CXADR LOC100357024 LOC100357024 SYT2-2 SYT2-2 ENSOCUP00000042868 ENSOCUP00000042868 INSR INSR VGLL4 VGLL4 DLL1 DLL1 PROX1 PROX1 ENSOCUP00000040918 ENSOCUP00000040918 ENSOCUP00000040871 ENSOCUP00000040871 IL7 IL7 DNM2 DNM2 ENSOCUP00000037873 ENSOCUP00000037873 MBD5 MBD5 SEMA4A SEMA4A ENSOCUP00000037776 ENSOCUP00000037776 WWC1 WWC1 RAB21 RAB21 BMPR2 BMPR2 BDNF BDNF PLCB1 PLCB1 BCL2 BCL2 KCNK2 KCNK2 ERBB4 ERBB4 TGFBR1 TGFBR1 SEMA6A SEMA6A CDKL5 CDKL5 MYCBP2 MYCBP2 CAPN3 CAPN3 GSK3B GSK3B ENSOCUP00000034349 ENSOCUP00000034349 MAEL MAEL RGS2 RGS2 FGFR2 FGFR2 YBX3 YBX3 SIN3A SIN3A ENSOCUP00000033961 ENSOCUP00000033961 WNT3 WNT3 DIP2B DIP2B SYT17 SYT17 MTM1 MTM1 FTO FTO CTTN CTTN FLVCR1 FLVCR1 ITSN2 ITSN2 L1CAM L1CAM LOC103348513 LOC103348513 NKX6-1 NKX6-1 DIO3 DIO3 BBS4 BBS4 FOXS1 FOXS1 RAG2 RAG2 RYK RYK DBN1 DBN1 REG1A REG1A GLI1 GLI1 IGF1 IGF1 TWF2 TWF2 PARK2 PARK2 TBX2 TBX2 MAG MAG DUSP9 DUSP9 CAV3 CAV3 LPAR3 LPAR3 LIMK1 LIMK1 GSK3A GSK3A CDK5 CDK5 G1U373_RABIT G1U373_RABIT PARP2 PARP2 HAMP HAMP ARX ARX ACTN3 ACTN3 STAT5A STAT5A SYT1 SYT1 MYOD1 MYOD1 FSTL4 FSTL4 POU4F2 POU4F2 CDK4 CDK4 RTN4 RTN4 PIM1 PIM1 SEMA3D SEMA3D TNKS2 TNKS2 PPIB PPIB SEMA3A SEMA3A SEMA3F SEMA3F DRD2 DRD2 RNF157 RNF157 BMP4 BMP4 STAT3 STAT3 CYFIP1 CYFIP1 GDF5 GDF5 APP APP DISC1 DISC1 BMP10 BMP10 LEP LEP CPNE9 CPNE9 CHD7 CHD7 RUFY3 RUFY3 JARID2 JARID2 SYT4 SYT4 PPARA PPARA RND2 RND2 IST1 IST1 PTEN PTEN ANKRD26 ANKRD26 SEMA3G SEMA3G GPAM GPAM G6PD G6PD DUSP10 DUSP10 ACACB ACACB BCL2L11 BCL2L11 GHSR GHSR CRABP2 CRABP2 FOXP1 FOXP1 G1SSD9_RABIT G1SSD9_RABIT OSTN OSTN SLC23A2 SLC23A2 SEMA5B SEMA5B HLX HLX ZFPM2 ZFPM2 NIPBL NIPBL WT1 WT1 GHRH GHRH LGMN LGMN DRAXIN DRAXIN CREB1 CREB1 TRPV2 TRPV2 NKD1 NKD1 HOPX HOPX STAT5B STAT5B MAP3K13 MAP3K13 SEMA4F SEMA4F NRP1 NRP1 STK3 STK3 GH1 GH1 SEMA5A SEMA5A BARHL2 BARHL2 TTL TTL SLIT1 SLIT1 SLC6A4 SLC6A4 SPTBN4 SPTBN4 SEMA4C SEMA4C WDR36 WDR36 STK4 STK4 PTCH1 PTCH1 DUSP6 DUSP6 SRF SRF MKKS MKKS CDK1 CDK1 SEMA4G SEMA4G SEMA6C SEMA6C SEMA3B SEMA3B G1SGL1_RABIT G1SGL1_RABIT TSHR TSHR ZFYVE27 ZFYVE27 CELF1 CELF1 PRL PRL TOMM70 TOMM70 SOCS2 SOCS2 BCL11A BCL11A ARHGAP4 ARHGAP4 MFSD2A MFSD2A SPAG9 SPAG9 KIAA0319 KIAA0319 MUL1 MUL1 FGF2 FGF2 WNT5A WNT5A NKX2-5 NKX2-5
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (274 aa)
SYT2Synaptotagmin 2. (286 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1001 aa)
CSF1Colony stimulating factor 1. (535 aa)
DPYSL2Dihydropyrimidinase like 2. (572 aa)
G1U9D6_RABITUncharacterized protein. (105 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC103351908Homeobox domain-containing protein. (408 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
PLAC8Placenta associated 8. (114 aa)
GOLGA4Golgin A4. (2199 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)
SHTN1Shootin 1. (613 aa)
PPARDUncharacterized protein. (420 aa)
CDKL3Cyclin dependent kinase like 3. (673 aa)
PLXNA4Plexin A4. (1912 aa)
MAPTMicrotubule-associated protein. (840 aa)
MAP2Microtubule-associated protein. (1921 aa)
TBX20T-box transcription factor 20. (460 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
RASAL1RAS protein activator like 1. (1200 aa)
SEMA7ASema domain-containing protein; Belongs to the semaphorin family. (408 aa)
SAV1Salvador family WW domain containing protein 1. (392 aa)
MSTNMyostatin. (375 aa)
ATRNAttractin. (1426 aa)
TBX5T-box transcription factor 5. (518 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (864 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (202 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
AKAP6A-kinase anchoring protein 6. (2318 aa)
SIX1SIX homeobox 1. (284 aa)
NPPCUncharacterized protein. (351 aa)
ADNPActivity dependent neuroprotector homeobox. (1104 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (832 aa)
FXNFrataxin. (211 aa)
IFRD1Interferon related developmental regulator 1. (451 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
PLAAPhospholipase A2 activating protein. (795 aa)
RNF6Ring finger protein 6. (683 aa)
ZP3Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (419 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
CDKN1AUncharacterized protein. (231 aa)
ADRB2Adrenoceptor beta 2. (437 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (456 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (360 aa)
G1TBF0_RABITANK_REP_REGION domain-containing protein. (621 aa)
SMURF1E3 ubiquitin-protein ligase. (737 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WWC2WW and C2 domain containing 2. (1082 aa)
NOL12Uncharacterized protein. (299 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
PLS1Plastin 1. (630 aa)
SPARTSpartin. (679 aa)
TNRTenascin R. (1359 aa)
MUSKReceptor protein-tyrosine kinase. (876 aa)
G1TET4_RABITUncharacterized protein. (1011 aa)
LOC100346323Uncharacterized protein. (240 aa)
MEGF8Uncharacterized protein. (439 aa)
DSPPUncharacterized protein. (657 aa)
SOX15SRY-box transcription factor 15. (227 aa)
NTN1Netrin 1. (533 aa)
PEX5Peroxisomal biogenesis factor 5. (660 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
SMAD7Mothers against decapentaplegic homolog. (549 aa)
PRLHProlactin releasing hormone. (87 aa)
VIL1Villin 1. (813 aa)
G1TQX9_RABITUncharacterized protein. (475 aa)
MYOZ1Uncharacterized protein. (310 aa)
GNASGNAS complex locus. (977 aa)
LATS1Large tumor suppressor kinase 1. (1124 aa)
TRIM46Tripartite motif containing 46. (907 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1066 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa)
LATS2Large tumor suppressor kinase 2. (1142 aa)
TLL2Tolloid like 2. (668 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (249 aa)
LOC103349690DUF3496 domain-containing protein. (645 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1620 aa)
ENSOCUP00000046773Protein kinase domain-containing protein. (249 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa)
UBE2D4Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (712 aa)
MAP1BMicrotubule associated protein 1B. (2355 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
ENSOCUP00000044310ANK_REP_REGION domain-containing protein. (624 aa)
CXADRUncharacterized protein. (362 aa)
LOC100357024Uncharacterized protein; Belongs to the parvalbumin family. (144 aa)
SYT2-2Uncharacterized protein. (81 aa)
ENSOCUP00000042868RBR-type E3 ubiquitin transferase. (139 aa)
INSRTyrosine-protein kinase receptor. (1377 aa)
VGLL4Vestigial like family member 4. (352 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (754 aa)
PROX1Prospero homeobox 1. (737 aa)
ENSOCUP00000040918Protein kinase domain-containing protein. (81 aa)
ENSOCUP00000040871Uncharacterized protein. (164 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (846 aa)
ENSOCUP00000037873Uncharacterized protein. (411 aa)
MBD5Methyl-CpG binding domain protein 5. (1732 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (977 aa)
ENSOCUP00000037776Uncharacterized protein. (514 aa)
WWC1WW and C2 domain containing 1. (1107 aa)
RAB21RAB21, member RAS oncogene family. (273 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (265 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (469 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (486 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1038 aa)
CDKL5Cyclin dependent kinase like 5. (1001 aa)
MYCBP2RING-type domain-containing protein. (275 aa)
CAPN3Uncharacterized protein; Belongs to the peptidase C2 family. (820 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
ENSOCUP00000034349Uncharacterized protein. (160 aa)
MAELMaelstrom spermatogenic transposon silencer. (512 aa)
RGS2RGS domain-containing protein. (229 aa)
FGFR2Fibroblast growth factor receptor. (894 aa)
YBX3Y-box binding protein 3. (453 aa)
SIN3ASIN3 transcription regulator family member A. (1241 aa)
ENSOCUP00000033961ANK_REP_REGION domain-containing protein. (226 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
DIP2BDisco interacting protein 2 homolog B. (1621 aa)
SYT17Synaptotagmin 17. (474 aa)
MTM1Myotubularin 1. (658 aa)
FTOFTO_NTD domain-containing protein. (504 aa)
CTTNCortactin. (653 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (552 aa)
ITSN2Intersectin 2. (1634 aa)
L1CAMUncharacterized protein. (1256 aa)
LOC103348513Uncharacterized protein. (322 aa)
NKX6-1NK6 homeobox 1. (369 aa)
DIO3Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (342 aa)
BBS4Bardet-Biedl syndrome 4. (493 aa)
FOXS1Forkhead box S1. (330 aa)
RAG2V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
RYKReceptor like tyrosine kinase. (553 aa)
DBN1Drebrin 1. (623 aa)
REG1ARegenerating family member 1 alpha. (182 aa)
GLI1GLI family zinc finger 1. (1103 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
PARK2E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (394 aa)
TBX2T-box transcription factor 2. (662 aa)
MAGUncharacterized protein. (58 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (465 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
LIMK1LIM domain kinase 1. (645 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
G1U373_RABITSRCR domain-containing protein; Belongs to the heparin-binding growth factors family. (200 aa)
PARP2Poly [ADP-ribose] polymerase. (566 aa)
HAMPHepcidin antimicrobial peptide. (83 aa)
ARXAristaless related homeobox. (518 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (900 aa)
STAT5ASignal transducer and activator of transcription. (793 aa)
SYT1Synaptotagmin 1. (447 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (323 aa)
FSTL4Follistatin like 4. (807 aa)
POU4F2POU domain protein. (392 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (392 aa)
RTN4Reticulon. (1110 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
TNKS2Poly [ADP-ribose] polymerase. (1283 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (770 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (784 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
RNF157Ring finger protein 157. (639 aa)
BMP4Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1272 aa)
GDF5Growth differentiation factor 5 preproprotein (Predicted). (500 aa)
APPGamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa)
DISC1DISC1 scaffold protein. (859 aa)
BMP10Bone morphogenetic protein 10. (428 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CPNE9Copine family member 9. (516 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
RUFY3RUN and FYVE domain containing 3. (617 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1242 aa)
SYT4Synaptotagmin 4. (425 aa)
PPARAPeroxisome proliferator activated receptor alpha. (503 aa)
RND2Rho family GTPase 2. (291 aa)
IST1IST1 factor associated with ESCRT-III. (372 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ANKRD26Ankyrin repeat domain 26. (1661 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (777 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (844 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (581 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
ACACBAcetyl-CoA carboxylase beta. (2373 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (194 aa)
GHSRGrowth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). (366 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
FOXP1Fork-head domain-containing protein. (714 aa)
G1SSD9_RABITRGS domain-containing protein. (183 aa)
OSTNOsteocrin. (132 aa)
SLC23A2Solute carrier family 23 member 2. (651 aa)
SEMA5BSemaphorin 5B. (1077 aa)
HLXH2.0 like homeobox. (682 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1159 aa)
NIPBLNipped-B protein. (2580 aa)
WT1WT1 transcription factor. (302 aa)
GHRHGrowth hormone releasing hormone. (106 aa)
LGMNLegumain. (435 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (337 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2. (817 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (472 aa)
HOPXHomeobox domain-containing protein. (73 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1009 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (721 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (950 aa)
STK3Serine/threonine kinase 3. (491 aa)
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (216 aa)
SEMA5ASemaphorin 5A. (978 aa)
BARHL2BarH like homeobox 2. (387 aa)
TTLTubulin tyrosine ligase. (377 aa)
SLIT1Slit guidance ligand 1. (1452 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (777 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (1822 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (832 aa)
WDR36WD repeat domain 36. (895 aa)
STK4Uncharacterized protein. (487 aa)
PTCH1Patched 1. (1321 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
SRFSerum response factor. (685 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (843 aa)
SEMA6CSema domain-containing protein; Belongs to the semaphorin family. (948 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (757 aa)
G1SGL1_RABITANK_REP_REGION domain-containing protein. (312 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (416 aa)
CELF1CUGBP Elav-like family member 1. (512 aa)
PRLProlactin; Prolactin acts primarily on the mammary gland by promoting lactation. (262 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
SOCS2Suppressor of cytokine signaling 2. (307 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (975 aa)
ARHGAP4Rho GTPase activating protein 4. (924 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (551 aa)
SPAG9Sperm associated antigen 9. (1149 aa)
KIAA0319KIAA0319. (1139 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa)
WNT5AProtein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa)
NKX2-5NK2 homeobox 5. (326 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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