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| | THBS1 | Thrombospondin 1. (1171 aa) |
| | CCR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | ENSOCUP00000048582 | Cu2_monoox_C domain-containing protein. (356 aa) |
| | CDC42 | Uncharacterized protein. (191 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (1000 aa) |
| | ENSOCUP00000047273 | Uncharacterized protein. (231 aa) |
| | ZNF304 | Zinc finger protein 304. (676 aa) |
| | ENSOCUP00000046773 | Protein kinase domain-containing protein. (249 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | HPN | Hepsin; Belongs to the peptidase S1 family. (579 aa) |
| | RIDA | Uncharacterized protein. (137 aa) |
| | LIMS2 | LIM zinc finger domain containing 2. (439 aa) |
| | DAB2 | DAB adaptor protein 2. (769 aa) |
| | ENSOCUP00000045056 | PDZ domain-containing protein. (145 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | PTPRM | Protein tyrosine phosphatase receptor type M. (1549 aa) |
| | OVOL2 | Ovo like zinc finger 2. (333 aa) |
| | TGM1 | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity). (833 aa) |
| | GRN | Granulin precursor. (626 aa) |
| | CDH3 | Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (1102 aa) |
| | AQP11 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (332 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1472 aa) |
| | ENSOCUP00000043082 | Uncharacterized protein. (319 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (823 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (511 aa) |
| | RB1 | RB transcriptional corepressor 1. (943 aa) |
| | ENSOCUP00000040918 | Protein kinase domain-containing protein. (81 aa) |
| | VASH2 | Vasohibin 2. (378 aa) |
| | IFT57 | Intraflagellar transport 57. (452 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | ENSOCUP00000039970 | Raptor_N domain-containing protein. (253 aa) |
| | STAT1 | Signal transducer and activator of transcription. (879 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (349 aa) |
| | ENSOCUP00000037873 | Uncharacterized protein. (411 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | MAP2K5 | Mitogen-activated protein kinase kinase 5. (551 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa) |
| | DLX5 | Distal-less homeobox 5. (313 aa) |
| | SP1 | Sp1 transcription factor. (792 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa) |
| | LOC100357982 | BZIP domain-containing protein. (301 aa) |
| | NOTCH2 | Notch receptor 2. (2481 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (486 aa) |
| | ENSOCUP00000035591 | Uncharacterized protein. (89 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (605 aa) |
| | ENSOCUP00000035160 | Ig domain-containing protein. (246 aa) |
| | BIRC5 | Uncharacterized protein. (164 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (894 aa) |
| | C5AR2 | Complement component 5a receptor 2. (370 aa) |
| | MMRN2 | Multimerin 2. (925 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2. (428 aa) |
| | APELA | Uncharacterized protein. (54 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (873 aa) |
| | CTNNB1 | Catenin beta 1. (741 aa) |
| | NFIB | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (586 aa) |
| | TRIM24 | Tripartite motif containing 24. (965 aa) |
| | WDR77 | WD repeat domain 77. (424 aa) |
| | ENSOCUP00000032595 | Runt domain-containing protein. (357 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (588 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | STXBP4 | Syntaxin binding protein 4. (555 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (371 aa) |
| | SAV1 | Salvador family WW domain containing protein 1. (392 aa) |
| | EPGN | Epithelial mitogen. (188 aa) |
| | ENSOCUP00000029917 | Uncharacterized protein. (169 aa) |
| | GHRL | Uncharacterized protein. (234 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (406 aa) |
| | F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (397 aa) |
| | PTN | Pleiotrophin. (242 aa) |
| | PPARD | Uncharacterized protein. (420 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (658 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (272 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. (773 aa) |
| | SMAD3 | SMAD family member 3. (230 aa) |
| | U3KPG4_RABIT | Uncharacterized protein. (481 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa) |
| | LOC100358984 | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (857 aa) |
| | LOC103351908 | Homeobox domain-containing protein. (408 aa) |
| | CRNN | Cornulin. (584 aa) |
| | U3KMS1_RABIT | Uncharacterized protein. (584 aa) |
| | G1U9D6_RABIT | Uncharacterized protein. (105 aa) |
| | MAGED1 | MAGE family member D1. (823 aa) |
| | CDC42-2 | Uncharacterized protein. (222 aa) |
| | G1U8R2_RABIT | Uncharacterized protein. (137 aa) |
| | OVOL1 | Ovo like transcriptional repressor 1. (251 aa) |
| | NME1 | Nucleoside diphosphate kinase. (152 aa) |
| | LOC100338481 | Uncharacterized protein. (101 aa) |
| | PRKCA | Protein kinase C alpha type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regul [...] (664 aa) |
| | GKN3P | Gastrokine 3, pseudogene. (188 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | AGGF1 | Uncharacterized protein. (752 aa) |
| | G1U5X9_RABIT | Uncharacterized protein. (99 aa) |
| | AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (836 aa) |
| | SYNJ2BP | PDZ domain-containing protein. (145 aa) |
| | ARX | Aristaless related homeobox. (518 aa) |
| | C5AR1 | C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (By similarity). (348 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | HOXA5 | Homeobox A5. (381 aa) |
| | AIMP1 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (334 aa) |
| | SCG2 | Secretogranin II. (621 aa) |
| | SIRT1 | Sirtuin 1. (748 aa) |
| | HAS2 | Uncharacterized protein. (556 aa) |
| | G1TYD7_RABIT | Uncharacterized protein. (101 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (279 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa) |
| | G1TXJ9_RABIT | Uncharacterized protein. (107 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (870 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | GLI1 | GLI family zinc finger 1. (1103 aa) |
| | REG1A | Regenerating family member 1 alpha. (182 aa) |
| | PPP1R16B | Protein phosphatase 1 regulatory subunit 16B. (421 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | TINF2 | TERF1 interacting nuclear factor 2. (356 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | ROBO1 | Roundabout guidance receptor 1. (1651 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (787 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) |
| | G1SFK6_RABIT | Uncharacterized protein. (93 aa) |
| | PDCL3 | Phosducin like 3. (240 aa) |
| | IFT74 | Intraflagellar transport 74. (600 aa) |
| | PRL | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. (262 aa) |
| | INTU | Inturned planar cell polarity protein. (944 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2. (719 aa) |
| | XDH | Uncharacterized protein. (1333 aa) |
| | LOC100339409 | Uncharacterized protein. (106 aa) |
| | PHOX2B | Homeobox domain-containing protein. (178 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (636 aa) |
| | IL26 | Interleukin 26. (180 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa) |
| | HMGN1 | Uncharacterized protein. (101 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | CCL24 | SCY domain-containing protein. (113 aa) |
| | EGR3 | Early growth response 3. (386 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (418 aa) |
| | NKX2-5 | NK2 homeobox 5. (326 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (369 aa) |
| | PTCH1 | Patched 1. (1321 aa) |
| | STK4 | Uncharacterized protein. (487 aa) |
| | SULF1 | Sulfatase 1. (846 aa) |
| | ZFP36 | ZFP36 ring finger protein. (338 aa) |
| | IQGAP3 | IQ motif containing GTPase activating protein 3. (1720 aa) |
| | BMP6 | Bone morphogenetic protein 6. (411 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | G1TUZ5_RABIT | Uncharacterized protein. (93 aa) |
| | APLN | Apelin. (77 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | RAP1GAP | RAP1 GTPase activating protein. (657 aa) |
| | NLRC3 | NLR family CARD domain containing 3. (992 aa) |
| | ODAM | Odontogenic, ameloblast associated. (279 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | PAX6 | Uncharacterized protein. (436 aa) |
| | OSR2 | Odd-skipped related transciption factor 2. (312 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) |
| | RREB1 | Ras responsive element binding protein 1. (1551 aa) |
| | G1TN23_RABIT | SCY domain-containing protein. (116 aa) |
| | FUT2 | Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway. (340 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1479 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | VDR | Vitamin D receptor. (368 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (327 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (245 aa) |
| | SOX11 | Transcription factor SOX. (446 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (125 aa) |
| | CPB2 | Carboxypeptidase B2. (424 aa) |
| | ATP5IF1 | Uncharacterized protein. (148 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | FLCN | Folliculin. (579 aa) |
| | TEK | TEK receptor tyrosine kinase. (1025 aa) |
| | PEX2 | Peroxisomal biogenesis factor 2. (305 aa) |
| | G1TDL7_RABIT | Uncharacterized protein. (125 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (491 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (373 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa) |
| | JAML | Uncharacterized protein. (388 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (590 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3412 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (375 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | PLXNB3 | Plexin B3. (1844 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa) |
| | CDC73 | Cell division cycle 73. (728 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (360 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (851 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (1105 aa) |
| | NKX2-8 | NK2 homeobox 8. (236 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | G1T8C0_RABIT | Uncharacterized protein. (311 aa) |
| | IFT80 | Intraflagellar transport 80. (777 aa) |
| | G1T805_RABIT | SEA domain-containing protein. (248 aa) |
| | PGR | Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation; Belongs to the nuclear hormone receptor family. NR3 subfamily. (930 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa) |
| | WDR13 | WD repeat domain 13. (478 aa) |
| | TBX1 | Uncharacterized protein. (440 aa) |
| | ATP7A | ATPase copper transporting alpha. (1499 aa) |
| | JCAD | Junctional cadherin 5 associated. (1271 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | TACSTD2 | Tumor associated calcium signal transducer 2. (327 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa) |
| | DAB2IP | DAB2 interacting protein. (1178 aa) |
| | GDF2 | Growth differentiation factor 2. (434 aa) |
| | HTRA1 | HtrA serine peptidase 1. (338 aa) |
| | ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (356 aa) |
| | PAX2 | Paired box 2. (448 aa) |
| | NOD2 | Nucleotide oligomerization domain 2 protein. (1013 aa) |
| | PROK1 | Prokineticin 1. (105 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | SNAI2 | Uncharacterized protein. (268 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (498 aa) |
| | SPARC | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (315 aa) |
| | RTN4 | Reticulon. (1110 aa) |
| | ECM1 | Extracellular matrix protein 1. (563 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (784 aa) |
| | RUNX2 | RUNX family transcription factor 2. (343 aa) |
| | BMP2 | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. (271 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | TNMD | Myodulin. (317 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa) |
| | BMP4 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | GDF5 | Growth differentiation factor 5 preproprotein (Predicted). (500 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1193 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (827 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | HSF4 | Heat shock transcription factor 4. (491 aa) |
| | SRSF6 | Serine/arginine-rich-splicing factor 6. (215 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | VASH1 | Vasohibin 1. (369 aa) |
| | THBS4 | Thrombospondin 4. (997 aa) |
| | TBC1D31 | TBC1 domain family member 31. (1067 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (622 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (732 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | MTSS1 | MTSS I-BAR domain containing 1. (892 aa) |
| | DLX6 | Distal-less homeobox 6. (164 aa) |
| | NF1 | Neurofibromin 1. (2841 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | MMP12 | Macrophage metalloelastase; May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). Belongs to the peptidase M10A family. (464 aa) |
| | KDM5B | Lysine demethylase 5B. (1537 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1847 aa) |
| | G1STJ2_RABIT | Uncharacterized protein. (217 aa) |
| | NGFR | Nerve growth factor receptor. (407 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | ENG | Endoglin. (758 aa) |
| | EAF2 | ELL associated factor 2. (263 aa) |
| | XBP1 | X-box binding protein 1. (208 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | IFT52 | Intraflagellar transport 52. (752 aa) |
| | PROK2 | Prokineticin 2. (106 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1080 aa) |
| | CD109 | CD109 molecule. (1318 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | KDF1 | Keratinocyte differentiation factor 1. (398 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (266 aa) |
| | HLX | H2.0 like homeobox. (682 aa) |
| | HYAL1 | Hyaluronidase. (497 aa) |
| | WDR48 | WD repeat domain 48. (867 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | IL18 | Uncharacterized protein. (408 aa) |
| | KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | PDX1 | Pancreatic and duodenal homeobox 1. (336 aa) |
| | ERRFI1 | ERBB receptor feedback inhibitor 1. (459 aa) |
| | KRIT1 | Uncharacterized protein. (736 aa) |
| | STK3 | Serine/threonine kinase 3. (491 aa) |
| | IFT172 | Intraflagellar transport 172. (1749 aa) |
| | NKX2-6 | NK2 homeobox 6. (294 aa) |
| | NKX3-1 | NK3 homeobox 1. (159 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (3985 aa) |
| | IRF6 | Interferon regulatory factor 6. (564 aa) |
| | A4GNT | Alpha-1,4-N-acetylglucosaminyltransferase. (340 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
