STRINGSTRING
DUSP22 DUSP22 ISG15 ISG15 TRAFD1 TRAFD1 CLEC4G CLEC4G NMI NMI LOC103345451 LOC103345451 TRIM27 TRIM27 ENSOCUP00000032553 ENSOCUP00000032553 IL20RB IL20RB WDR41 WDR41 DCST1 DCST1 SERPING1 SERPING1 NPY5R NPY5R INPP5D INPP5D FER FER CD59 CD59 STAT6 STAT6 FCRLB FCRLB SAMHD1 SAMHD1 PGLYRP2 PGLYRP2 DUSP10 DUSP10 LOC103348991 LOC103348991 ENSOCUP00000037243 ENSOCUP00000037243 ENSOCUP00000037329 ENSOCUP00000037329 LOC100346703 LOC100346703 ATG12 ATG12 C4BPA C4BPA IL33 IL33 FGL2 FGL2 NCKAP1L NCKAP1L DHX58 DHX58 TBX21 TBX21 IL4R IL4R METTL3 METTL3 PSMA1 PSMA1 NLRC5 NLRC5 MUL1 MUL1 NOD2 NOD2 PTPRC PTPRC DRD2 DRD2 THOC1 THOC1 FOXJ1 FOXJ1 IL7R IL7R GPR17 GPR17 ZC3H12A ZC3H12A HMOX1 HMOX1 FOXP3 FOXP3 IL2 IL2 RC3H2 RC3H2 SPINK5 SPINK5 G1SV95_RABIT G1SV95_RABIT MMP12 MMP12 BANF1 BANF1 FAM3A FAM3A PGLYRP1 PGLYRP1 CLEC12B CLEC12B CSMD3 CSMD3 TYRO3 TYRO3 HLX HLX SERPINB9 SERPINB9 RC3H1 RC3H1 VSIG4 VSIG4 PARP14 PARP14 LYAR LYAR TNFAIP3 TNFAIP3 PSMB4 PSMB4 RABGEF1 RABGEF1 COL3A1 COL3A1 IL13RA2 IL13RA2 CNOT7 CNOT7 IL27RA IL27RA IRAK3 IRAK3 ENPP3 ENPP3 SAMSN1 SAMSN1 IL12B IL12B IL1RL1 IL1RL1 FOXF1 FOXF1 YTHDF2 YTHDF2 TNFSF18 TNFSF18 ANXA1 ANXA1 ALOX15 ALOX15 SELENOS SELENOS SMAD7 SMAD7 G1TPZ5_RABIT G1TPZ5_RABIT YTHDF3 YTHDF3 ADAR ADAR ENSOCUP00000048359 ENSOCUP00000048359 CD84 CD84 ENSOCUP00000045925 ENSOCUP00000045925 ACOD1 ACOD1 BCL6 BCL6 CD55 CD55 ENSOCUP00000044284 ENSOCUP00000044284 GRN GRN MKRN2 MKRN2 ATG5 ATG5 AHR AHR USP15 USP15 DNAJA3 DNAJA3 PDCD1 PDCD1 ENSOCUP00000041840 ENSOCUP00000041840 LOC100348748 LOC100348748 PTPN2 PTPN2 STAT2 STAT2 ENSOCUP00000039002 ENSOCUP00000039002 CD300A CD300A LOC100344662 LOC100344662 PPP3CB PPP3CB NLRC3 NLRC3 TREX1 TREX1 INS INS IFNB1 IFNB1 OTOP1 OTOP1 NLRX1 NLRX1 LOC100358544 LOC100358544 HFE HFE SMCR8 SMCR8 SLAMF1 SLAMF1 TTLL12 TTLL12 SLAMF8 SLAMF8 CD96 CD96 ARG1 ARG1 KLRD1 KLRD1 NDFIP1 NDFIP1 BCR BCR PARP3 PARP3 CR2 CR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DUSP22Uncharacterized protein. (319 aa)
ISG15ISG15 ubiquitin like modifier. (164 aa)
TRAFD1TRAF-type zinc finger domain containing 1. (655 aa)
CLEC4GC-type lectin domain-containing protein. (421 aa)
NMIN-myc and STAT interactor. (367 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
TRIM27Tripartite motif containing 27. (513 aa)
ENSOCUP00000032553PROTEASOME_ALPHA_1 domain-containing protein. (168 aa)
IL20RBInterleukin 20 receptor subunit beta. (307 aa)
WDR41WD_REPEATS_REGION domain-containing protein. (278 aa)
DCST1DC-STAMP domain containing 1. (749 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (521 aa)
NPY5RNeuropeptide Y receptor Y5. (455 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (910 aa)
FERTyrosine-protein kinase. (452 aa)
CD59CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. (291 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
FCRLBFc receptor like B. (426 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (616 aa)
PGLYRP2Peptidoglycan recognition protein 2. (530 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
LOC103348991C-type lectin domain-containing protein. (256 aa)
ENSOCUP00000037243Uncharacterized protein. (60 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
LOC100346703Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (141 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (131 aa)
C4BPAComplement component 4 binding protein alpha. (635 aa)
IL33Uncharacterized protein. (142 aa)
FGL2Fibrinogen like 2. (441 aa)
NCKAP1LNCK associated protein 1 like. (1181 aa)
DHX58DExH-box helicase 58. (756 aa)
TBX21T-box transcription factor 21. (520 aa)
IL4RFibronectin type-III domain-containing protein. (862 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
NLRC5NLR family CARD domain containing 5. (1774 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
NOD2Nucleotide oligomerization domain 2 protein. (1013 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
THOC1THO complex 1. (657 aa)
FOXJ1Forkhead box J1. (421 aa)
IL7RInterleukin 7 receptor. (458 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (419 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (580 aa)
HMOX1Heme oxygenase 1. (288 aa)
FOXP3Forkhead box P3. (455 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (153 aa)
RC3H2Ring finger and CCCH-type domains 2. (1132 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1087 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
MMP12Macrophage metalloelastase; May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). Belongs to the peptidase M10A family. (464 aa)
BANF1Uncharacterized protein. (188 aa)
FAM3AFamily with sequence similarity 3 member A. (230 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (197 aa)
CLEC12BC-type lectin domain family 12 member B. (276 aa)
CSMD3CUB and Sushi multiple domains 3. (3683 aa)
TYRO3TYRO3 protein tyrosine kinase. (860 aa)
HLXH2.0 like homeobox. (682 aa)
SERPINB9Serpin family B member 9; Belongs to the serpin family. (376 aa)
RC3H1Ring finger and CCCH-type domains 1. (1134 aa)
VSIG4V-set and immunoglobulin domain containing 4. (411 aa)
PARP14Poly [ADP-ribose] polymerase. (1790 aa)
LYARLy1 antibody reactive. (377 aa)
TNFAIP3TNF alpha induced protein 3. (787 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
RABGEF1Uncharacterized protein. (492 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (361 aa)
CNOT7Uncharacterized protein. (285 aa)
IL27RAInterleukin 27 receptor subunit alpha. (634 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (593 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (940 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (280 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa)
IL1RL1Interleukin 1 receptor like 1. (550 aa)
FOXF1Forkhead box F1. (433 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (579 aa)
TNFSF18TNF superfamily member 18. (217 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (334 aa)
ALOX15Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (674 aa)
SELENOSUncharacterized protein. (317 aa)
SMAD7Mothers against decapentaplegic homolog. (549 aa)
G1TPZ5_RABITUncharacterized protein. (551 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (602 aa)
ADARAdenosine deaminase RNA specific. (1182 aa)
ENSOCUP00000048359Uncharacterized protein. (127 aa)
CD84CD84 molecule. (345 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
ACOD1Aconitate decarboxylase 1. (499 aa)
BCL6BCL6 transcription repressor. (723 aa)
CD55Uncharacterized protein. (430 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
GRNGranulin precursor. (626 aa)
MKRN2Makorin ring finger protein 2. (424 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (245 aa)
AHRAryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] (887 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (997 aa)
DNAJA3Uncharacterized protein. (479 aa)
PDCD1Ig-like domain-containing protein. (367 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
LOC100348748IGv domain-containing protein. (604 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
STAT2STAT_int domain-containing protein. (205 aa)
ENSOCUP00000039002Uncharacterized protein. (163 aa)
CD300AIg-like domain-containing protein. (384 aa)
LOC100344662Uncharacterized protein. (469 aa)
PPP3CBSerine/threonine-protein phosphatase. (518 aa)
NLRC3NLR family CARD domain containing 3. (992 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa)
IFNB1Interferon beta 1. (180 aa)
OTOP1Otopetrin 1. (556 aa)
NLRX1NLR family member X1. (803 aa)
LOC100358544Uncharacterized protein. (1025 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (356 aa)
SMCR8SMCR8-C9orf72 complex subunit. (930 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (340 aa)
TTLL12Uncharacterized protein. (65 aa)
SLAMF8SLAM family member 8. (312 aa)
CD96CD96 molecule. (495 aa)
ARG1Arginase-1. (348 aa)
KLRD1Killer cell lectin like receptor D1. (178 aa)
NDFIP1Nedd4 family interacting protein 1. (226 aa)
BCRBCR activator of RhoGEF and GTPase. (1192 aa)
PARP3Poly [ADP-ribose] polymerase. (537 aa)
CR2Complement C3d receptor 2. (1084 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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