Your Input: | |
| | ZC4H2 | Zinc finger C4H2-type containing. (224 aa) |
| | NOD2 | Nucleotide oligomerization domain 2 protein. (1013 aa) |
| | DDRGK1 | DDRGK domain containing 1. (418 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (487 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (498 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | SLCO3A1 | Solute carrier organic anion transporter family member. (651 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (670 aa) |
| | BMP2 | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. (271 aa) |
| | COPS5 | COP9 signalosome subunit 5. (334 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (848 aa) |
| | EP300 | E1A binding protein p300. (2418 aa) |
| | TRIM25 | RING-type domain-containing protein. (368 aa) |
| | LOC100343655 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1044 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (823 aa) |
| | APP | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa) |
| | BUD31 | BUD31 homolog. (144 aa) |
| | NTS | Neurotensin. (170 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | CSF3 | Colony stimulating factor 3. (204 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | RELN | Uncharacterized protein. (1813 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (798 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | CLUL1 | Clusterin; Belongs to the clusterin family. (469 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | TRIM62 | Tripartite motif containing 62. (366 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (497 aa) |
| | CTH | Cystathionine gamma-lyase. (411 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (404 aa) |
| | EIF2AK2 | Interferon-induced double-stranded RNA-activated protein kinase. (547 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | PPRC1 | PPARG related coactivator 1. (1646 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (848 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | RTKN2 | Rhotekin 2. (613 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (839 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | G1SI52_RABIT | Protein kinase domain-containing protein. (457 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (592 aa) |
| | SRF | Serum response factor. (685 aa) |
| | TSSK4 | Testis specific serine kinase 4. (342 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | TRIM41 | Uncharacterized protein. (633 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | TRIM14 | Tripartite motif containing 14. (489 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (161 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | NKX3-1 | NK3 homeobox 1. (159 aa) |
| | TRIM38 | Tripartite motif containing 38. (465 aa) |
| | ANKRD42 | Ankyrin repeat domain 42. (521 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | STK3 | Serine/threonine kinase 3. (491 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (598 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1009 aa) |
| | ESR2 | Estrogen receptor 2. (523 aa) |
| | G1SNG6_RABIT | B30.2/SPRY domain-containing protein. (202 aa) |
| | IL18 | Uncharacterized protein. (408 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | TNFRSF11A | TNFR-Cys domain-containing protein. (349 aa) |
| | MTPN | Myotrophin. (186 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | CLU | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (518 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (599 aa) |
| | PINK1 | PTEN induced kinase 1. (569 aa) |
| | ABRA | Actin binding Rho activating protein. (457 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (783 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | LRP8 | LDL receptor related protein 8. (1029 aa) |
| | ENSOCUP00000048431 | Uncharacterized protein. (123 aa) |
| | ENSOCUP00000047805 | Uncharacterized protein. (339 aa) |
| | TLR9 | TIR domain-containing protein. (1027 aa) |
| | PSMA6 | Proteasome endopeptidase complex. (264 aa) |
| | ENSOCUP00000046526 | Reelin domain-containing protein. (274 aa) |
| | STK36 | Serine/threonine kinase 36. (1371 aa) |
| | PRKCB | Protein kinase C beta type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR- induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser- [...] (638 aa) |
| | ENSOCUP00000046087 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa) |
| | ENSOCUP00000046066 | EGF-like domain-containing protein. (561 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (978 aa) |
| | ENSOCUP00000045339 | Uncharacterized protein. (163 aa) |
| | TRIM6 | Uncharacterized protein. (488 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (695 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (1125 aa) |
| | ENSOCUP00000044347 | KH type-2 domain-containing protein. (196 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | PLPP3 | acidPPc domain-containing protein. (331 aa) |
| | TRIM5 | Uncharacterized protein. (490 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | TRIM37 | Tripartite motif containing 37. (967 aa) |
| | ENSOCUP00000043061 | Uncharacterized protein. (103 aa) |
| | AR | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (925 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | TRIM8 | Tripartite motif containing 8. (571 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (335 aa) |
| | ITGB2 | Integrin beta. (1009 aa) |
| | PARK7 | Parkinsonism associated deglycase. (231 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (332 aa) |
| | CYTL1 | Uncharacterized protein. (195 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1180 aa) |
| | ENSOCUP00000038097 | Uncharacterized protein. (288 aa) |
| | SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (327 aa) |
| | CAMK1D | Calcium/calmodulin dependent protein kinase ID. (355 aa) |
| | ENSOCUP00000037873 | Uncharacterized protein. (411 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | FER | Tyrosine-protein kinase. (452 aa) |
| | ENSOCUP00000035684 | RWD domain-containing protein. (243 aa) |
| | ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1201 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (860 aa) |
| | CAPN3 | Uncharacterized protein; Belongs to the peptidase C2 family. (820 aa) |
| | ENSOCUP00000034710 | Uncharacterized protein. (391 aa) |
| | MYD88 | Uncharacterized protein. (476 aa) |
| | CD40 | Uncharacterized protein. (494 aa) |
| | ENSOCUP00000033799 | Uncharacterized protein. (545 aa) |
| | TRIM31 | Uncharacterized protein. (613 aa) |
| | CTNNB1 | Catenin beta 1. (741 aa) |
| | ENSOCUP00000032533 | ANK_REP_REGION domain-containing protein. (78 aa) |
| | TIRAP | TIR domain containing adaptor protein. (234 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1653 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | HSF1 | Heat shock transcription factor 1. (680 aa) |
| | MALT1 | MALT1 paracaspase. (799 aa) |
| | ENSOCUP00000031759 | Guanylate cyclase domain-containing protein. (312 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | ENSOCUP00000031352 | Uncharacterized protein. (51 aa) |
| | ENSOCUP00000031335 | TFIID_20kDa domain-containing protein. (217 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (1057 aa) |
| | SAV1 | Salvador family WW domain containing protein 1. (392 aa) |
| | ENSOCUP00000030661 | Thioredoxin domain-containing protein. (183 aa) |
| | ARID5B | AT-rich interaction domain 5B. (1191 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (534 aa) |
| | DHX9 | DExH-box helicase 9. (1298 aa) |
| | SPHK1 | Sphingosine kinase 1. (455 aa) |
| | ENSOCUP00000029409 | TORC_C domain-containing protein. (363 aa) |
| | RAB7B | Uncharacterized protein. (280 aa) |
| | STING1 | Transmembrane protein 173. (426 aa) |
| | FANK1 | Fibronectin type III and ankyrin repeat domains 1. (477 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (539 aa) |
| | TRAPPC9 | Trafficking protein particle complex 9. (1158 aa) |
| | PRDX3 | Thioredoxin domain-containing protein. (307 aa) |
| | ENSOCUP00000027355 | ANK_REP_REGION domain-containing protein. (78 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa) |
| | CRNN | Cornulin. (584 aa) |
| | THAP11 | THAP domain containing 11. (320 aa) |
| | G1U7S6_RABIT | Uncharacterized protein. (209 aa) |
| | DHX33 | DEAH-box helicase 33. (710 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (918 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (623 aa) |
| | RNF220 | Ring finger protein 220. (566 aa) |
| | G1U317_RABIT | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | MYOCD | Myocardin. (989 aa) |
| | RNF25 | Ring finger protein 25. (456 aa) |
| | NEUROG2 | Neurogenin 2. (274 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | G1U0P1_RABIT | Uncharacterized protein. (209 aa) |
| | G1TXZ4_RABIT | Uncharacterized protein. (975 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa) |
| | ZIC2 | Uncharacterized protein. (272 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (870 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (164 aa) |
| | ADGRF1 | Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (915 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) |
| | NDP | Norrin cystine knot growth factor NDP. (133 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1634 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (304 aa) |
| | DDX58 | DExD/H-box helicase 58. (954 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) |
| | TRADD | TNFRSF1A associated via death domain. (447 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | TRIM32 | Tripartite motif containing 32. (659 aa) |
| | G1TKQ0_RABIT | ANK_REP_REGION domain-containing protein. (118 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (401 aa) |
| | TNFSF18 | TNF superfamily member 18. (217 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | CIB1 | Uncharacterized protein. (143 aa) |
| | HDAC4 | Hist_deacetyl domain-containing protein. (279 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (495 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (708 aa) |
| | LOC100355132 | Uncharacterized protein. (539 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa) |
| | TLR3 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (867 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | TFRC | Transferrin receptor. (763 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa) |
| | IL18R1 | Uncharacterized protein. (540 aa) |
| | MBTPS2 | Membrane bound transcription factor peptidase, site 2. (531 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (360 aa) |
| | PRKCH | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa) |
| | CRTC2 | CREB regulated transcription coactivator 2. (652 aa) |
| | TRIM26 | Tripartite motif containing 26. (539 aa) |
| | TRIM15 | Tripartite motif containing 15. (469 aa) |
| | EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (386 aa) |
| | TERF2IP | TERF2 interacting protein. (397 aa) |
| | G1T8C0_RABIT | Uncharacterized protein. (311 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (593 aa) |
| | TRIML1 | Tripartite motif family like 1. (468 aa) |
| | TRIML2 | Tripartite motif family like 2. (437 aa) |
| | CRTC3 | CREB regulated transcription coactivator 3. (621 aa) |
| | RWDD1 | RWD domain-containing protein. (243 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (202 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
