node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA1 | ABCB11 | ENSOCUP00000046484 | ENSOCUP00000001184 | ATP binding cassette subfamily A member 1. | Bile salt export pump; Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine- conjugated bile salts. | 0.467 |
ABCA1 | ANGPTL3 | ENSOCUP00000046484 | ENSOCUP00000000783 | ATP binding cassette subfamily A member 1. | Angiopoietin like 3. | 0.434 |
ABCA1 | APOA1 | ENSOCUP00000046484 | ENSOCUP00000009241 | ATP binding cassette subfamily A member 1. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.997 |
ABCA1 | CETP | ENSOCUP00000046484 | ENSOCUP00000011306 | ATP binding cassette subfamily A member 1. | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | 0.864 |
ABCA1 | FABP3 | ENSOCUP00000046484 | ENSOCUP00000012556 | ATP binding cassette subfamily A member 1. | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.414 |
ABCA1 | GPAM | ENSOCUP00000046484 | ENSOCUP00000006821 | ATP binding cassette subfamily A member 1. | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | 0.406 |
ABCB11 | ABCA1 | ENSOCUP00000001184 | ENSOCUP00000046484 | Bile salt export pump; Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine- conjugated bile salts. | ATP binding cassette subfamily A member 1. | 0.467 |
ABCB11 | HNF4A | ENSOCUP00000001184 | ENSOCUP00000005917 | Bile salt export pump; Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine- conjugated bile salts. | Hepatocyte nuclear factor 4 alpha. | 0.449 |
ANGPTL3 | ABCA1 | ENSOCUP00000000783 | ENSOCUP00000046484 | Angiopoietin like 3. | ATP binding cassette subfamily A member 1. | 0.434 |
ANGPTL3 | APOA1 | ENSOCUP00000000783 | ENSOCUP00000009241 | Angiopoietin like 3. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.626 |
ANGPTL3 | CETP | ENSOCUP00000000783 | ENSOCUP00000011306 | Angiopoietin like 3. | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | 0.486 |
ANGPTL3 | GPAM | ENSOCUP00000000783 | ENSOCUP00000006821 | Angiopoietin like 3. | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | 0.440 |
ANGPTL3 | LIPG | ENSOCUP00000000783 | ENSOCUP00000036553 | Angiopoietin like 3. | PLAT domain-containing protein. | 0.448 |
APOA1 | ABCA1 | ENSOCUP00000009241 | ENSOCUP00000046484 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | ATP binding cassette subfamily A member 1. | 0.997 |
APOA1 | ANGPTL3 | ENSOCUP00000009241 | ENSOCUP00000000783 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Angiopoietin like 3. | 0.626 |
APOA1 | CETP | ENSOCUP00000009241 | ENSOCUP00000011306 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | 0.967 |
APOA1 | LIPG | ENSOCUP00000009241 | ENSOCUP00000036553 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | PLAT domain-containing protein. | 0.565 |
CETP | ABCA1 | ENSOCUP00000011306 | ENSOCUP00000046484 | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | ATP binding cassette subfamily A member 1. | 0.864 |
CETP | ANGPTL3 | ENSOCUP00000011306 | ENSOCUP00000000783 | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | Angiopoietin like 3. | 0.486 |
CETP | APOA1 | ENSOCUP00000011306 | ENSOCUP00000009241 | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.967 |