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| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (870 aa) |
| | SERPINF2 | SERPIN domain-containing protein; Belongs to the serpin family. (533 aa) |
| | CCL24 | SCY domain-containing protein. (113 aa) |
| | PDGFRA | Protein kinase domain-containing protein. (773 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa) |
| | IL26 | Interleukin 26. (180 aa) |
| | G1SDU7_RABIT | C-C motif chemokine. (104 aa) |
| | LOC100348776 | C-C motif chemokine. (93 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | CCL20 | C-C motif chemokine. (96 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa) |
| | GATA4 | GATA binding protein 4. (444 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (839 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (397 aa) |
| | CHRNA7 | Uncharacterized protein. (513 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | SLC30A10 | Solute carrier family 30 member 10. (479 aa) |
| | CCR1 | Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | CD74 | CD74 molecule. (375 aa) |
| | FGF19 | Fibroblast growth factor 19; Belongs to the heparin-binding growth factors family. (218 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (679 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (950 aa) |
| | KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | NPSR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (371 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | TNFRSF11A | TNFR-Cys domain-containing protein. (349 aa) |
| | DENND2B | Suppression of tumorigenicity 5. (1163 aa) |
| | PDGFA | Platelet-derived growth factor subunit A; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by t [...] (150 aa) |
| | HCRTR1 | Hypocretin receptor 1. (416 aa) |
| | NELFE | Negative elongation factor complex member E. (395 aa) |
| | THPO | Thrombopoietin. (348 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (404 aa) |
| | PLA2G5 | Phospholipase A(2). (246 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (780 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | ABL2 | Tyrosine-protein kinase. (1146 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) |
| | ENSOCUP00000049280 | SCY domain-containing protein. (136 aa) |
| | PHB | Prohibitin. (303 aa) |
| | ANGPT1 | Angiopoietin 1. (551 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | ENSOCUP00000042043 | Ig-like domain-containing protein. (212 aa) |
| | NOX4 | NADPH oxidase 4. (638 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | AKAP12 | A-kinase anchoring protein 12. (1740 aa) |
| | LOC100348748 | IGv domain-containing protein. (604 aa) |
| | RAP1A | Uncharacterized protein. (184 aa) |
| | CCL25 | SCY domain-containing protein. (159 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | GPNMB | Glycoprotein nmb. (569 aa) |
| | CCL19 | C-C motif chemokine. (109 aa) |
| | ABL1 | Tyrosine-protein kinase. (1118 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (862 aa) |
| | CCL7 | SCY domain-containing protein. (204 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (798 aa) |
| | CCL4 | C-C motif chemokine 4. (96 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | NOTCH2 | Notch receptor 2. (2481 aa) |
| | NPY5R | Neuropeptide Y receptor Y5. (455 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa) |
| | GLIPR2 | GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (894 aa) |
| | C5AR2 | Complement component 5a receptor 2. (370 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (231 aa) |
| | NRG1 | Neuregulin 1. (720 aa) |
| | GCNT2 | Uncharacterized protein. (402 aa) |
| | APELA | Uncharacterized protein. (54 aa) |
| | ENSOCUP00000033220 | Prohibitin. (262 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (873 aa) |
| | TIRAP | TIR domain containing adaptor protein. (234 aa) |
| | DSTYK | Dual serine/threonine and tyrosine protein kinase. (952 aa) |
| | FGG | Fibrinogen gamma chain. (450 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | OPRM1 | Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (419 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (767 aa) |
| | SEMA7A | Sema domain-containing protein; Belongs to the semaphorin family. (408 aa) |
| | PDE8A | Phosphodiesterase. (889 aa) |
| | CAVIN3 | Caveolae associated protein 3. (267 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (272 aa) |
| | FERMT2 | Fermitin family member 2. (696 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (534 aa) |
| | ALKAL2 | ALK and LTK ligand 2. (152 aa) |
| | ALKAL1 | ALK and LTK ligand 1. (129 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | NDRG4 | NDRG family member 4. (387 aa) |
| | OR2AT4 | Olfactory receptor. (313 aa) |
| | G1U7S6_RABIT | Uncharacterized protein. (209 aa) |
| | PRKCA | Protein kinase C alpha type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regul [...] (664 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (252 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (340 aa) |
| | C5AR1 | C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (By similarity). (348 aa) |
| | G1U373_RABIT | SRCR domain-containing protein; Belongs to the heparin-binding growth factors family. (200 aa) |
| | G1U2E9_RABIT | Uncharacterized protein. (108 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1. (1052 aa) |
| | P2RY8 | P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (327 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (131 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (460 aa) |
| | CXCL17 | C-X-C motif chemokine ligand 17. (122 aa) |
| | GCG | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). (180 aa) |
| | ARRB1 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] (408 aa) |
| | CCL17 | SCY domain-containing protein. (106 aa) |
| | SCIMP | SLP adaptor and CSK interacting membrane protein. (142 aa) |
| | CCL14 | C-C motif chemokine ligand 14. (94 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) |
| | GAREM2 | GRB2 associated regulator of MAPK1 subtype 2. (648 aa) |
| | G1TN23_RABIT | SCY domain-containing protein. (116 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (401 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (383 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (674 aa) |
| | CIB1 | Uncharacterized protein. (143 aa) |
| | G1TGC0_RABIT | Uncharacterized protein. (214 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | TEK | TEK receptor tyrosine kinase. (1025 aa) |
| | P2RY6 | Pyrimidinergic receptor P2Y6. (350 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | HAND2 | BHLH domain-containing protein. (426 aa) |
| | SHC1 | SHC adaptor protein 1. (474 aa) |
| | HTR2C | 5-hydroxytryptamine receptor 2C. (453 aa) |
| | CCL22 | C-C motif chemokine. (93 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | GAREM1 | GRB2 associated regulator of MAPK1 subtype 1. (923 aa) |
| | CCL1 | C-C motif chemokine. (190 aa) |
| | PRXL2C | Peroxiredoxin like 2C. (226 aa) |
| | LOC100349255 | SCY domain-containing protein. (114 aa) |
| | NOD2 | Nucleotide oligomerization domain 2 protein. (1013 aa) |
| | TNFAIP8L3 | TNF alpha induced protein 8 like 3. (204 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | BMP2 | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. (271 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (848 aa) |
| | DNAJC27 | DnaJ heat shock protein family (Hsp40) member C27. (283 aa) |
| | FGA | Fibrinogen alpha chain. (813 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (703 aa) |
| | FGB | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (492 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa) |
| | BMP4 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa) |
| | ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (336 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (823 aa) |
| | APP | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa) |
| | FFAR4 | Free fatty acid receptor 4. (361 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1193 aa) |
| | NPTN | Neuroplastin. (367 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (469 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1659 aa) |
