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| | FLRT2 | Fibronectin leucine rich transmembrane protein 2. (660 aa) |
| | CYSTM1 | Cysteine rich transmembrane module containing 1. (95 aa) |
| | TOLLIP | Toll interacting protein. (274 aa) |
| | KL | Klotho. (1005 aa) |
| | ARTN | Artemin. (218 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) |
| | IL1RN | Interleukin-1 receptor antagonist protein; Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity; Belongs to the IL-1 family. (221 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa) |
| | TSLP | Uncharacterized protein. (149 aa) |
| | G1U0P1_RABIT | Uncharacterized protein. (209 aa) |
| | IL37 | Interleukin-1. (280 aa) |
| | G1U373_RABIT | SRCR domain-containing protein; Belongs to the heparin-binding growth factors family. (200 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (252 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa) |
| | LOC100341111 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (351 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (272 aa) |
| | CCDC88A | Coiled-coil domain containing 88A. (2026 aa) |
| | LINGO2 | Leucine rich repeat and Ig domain containing 2. (606 aa) |
| | EPGN | Epithelial mitogen. (188 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (464 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (873 aa) |
| | SNX1 | Sorting nexin 1. (559 aa) |
| | ENSOCUP00000033859 | Uncharacterized protein. (176 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (231 aa) |
| | MYD88 | Uncharacterized protein. (476 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa) |
| | ATXN2 | Ataxin 2. (1136 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa) |
| | CNOT9 | CCR4-NOT transcription complex subunit 9. (299 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (491 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa) |
| | CD300LF | CD300 molecule like family member f. (314 aa) |
| | AREG | Amphiregulin. (275 aa) |
| | EREG | Epiregulin. (169 aa) |
| | SDCBP | Syndecan binding protein. (312 aa) |
| | SHC1 | SHC adaptor protein 1. (474 aa) |
| | GRAP | GRB2 related adaptor protein. (342 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PDGFD | Platelet-derived growth factor D, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity). (538 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (154 aa) |
| | IL36A | Interleukin-1. (156 aa) |
| | EFEMP1 | EGF containing fibulin extracellular matrix protein 1. (494 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa) |
| | NCSTN | Nicastrin. (667 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | DAB2IP | DAB2 interacting protein. (1178 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa) |
| | MS4A15 | Membrane spanning 4-domains A15. (291 aa) |
| | LOC100341366 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (345 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (267 aa) |
| | ECM1 | Extracellular matrix protein 1. (563 aa) |
| | ESM1 | Endothelial cell specific molecule 1. (231 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (827 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (974 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (153 aa) |
| | MS4A4A | Uncharacterized protein. (278 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | NPTN | Neuroplastin. (367 aa) |
| | CSF3 | Colony stimulating factor 3. (204 aa) |
| | KLB | Klotho beta. (1112 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (267 aa) |
| | TNK2 | Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (853 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | MS4A1 | Membrane spanning 4-domains A1. (298 aa) |
| | IL6ST | Interleukin 6 signal transducer. (918 aa) |
| | ERAP1 | Endoplasmic reticulum aminopeptidase 1. (1034 aa) |
| | PDCL2 | Phosducin like 2. (241 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (699 aa) |
| | PSPN | Persephin. (151 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (757 aa) |
| | IL9 | Interleukin 9. (143 aa) |
| | LINGO1 | Leucine rich repeat and Ig domain containing 1. (693 aa) |
| | YES1 | Tyrosine-protein kinase. (543 aa) |
| | PDGFA | Platelet-derived growth factor subunit A; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by t [...] (150 aa) |
| | CNTF | Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (199 aa) |
| | IL36RN | Interleukin-1. (296 aa) |
| | CD2AP | Uncharacterized protein. (636 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | FGF19 | Fibroblast growth factor 19; Belongs to the heparin-binding growth factors family. (218 aa) |
| | FAM83B | Family with sequence similarity 83 member B. (993 aa) |
| | CSF2 | Uncharacterized protein. (144 aa) |
| | LYN | Tyrosine-protein kinase. (636 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (159 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1330 aa) |
| | GLMN | Uncharacterized protein. (592 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa) |
| | FLRT3 | Fibronectin leucine rich transmembrane protein 3. (649 aa) |
| | TGFA | Transforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar (By similarity). Inhibitor of acid secretion. Inhibitor of aminopyrine uptake in parietal cells (in vitro). (185 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatoz [...] (356 aa) |
| | PDCL3 | Phosducin like 3. (240 aa) |
| | G1SED3_RABIT | Uncharacterized protein. (590 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa) |
| | PDGFRA | Protein kinase domain-containing protein. (773 aa) |
| | ENSOCUP00000049426 | Protein kinase domain-containing protein. (66 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | FER | Tyrosine-protein kinase. (452 aa) |
| | ENSOCUP00000036170 | SH3 domain-containing protein. (389 aa) |
| | FRS3 | IRS-type PTB domain-containing protein. (543 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (964 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | SNX4 | Sorting nexin 4. (452 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa) |
| | BTC | Betacellulin. (212 aa) |
| | ARF4-2 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (163 aa) |
| | SNX2 | Sorting nexin 2. (639 aa) |
| | FGF17 | Uncharacterized protein; Belongs to the heparin-binding growth factors family. (151 aa) |
| | ENSOCUP00000042043 | Ig-like domain-containing protein. (212 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (278 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | SRC | Tyrosine-protein kinase. (589 aa) |
| | ENSOCUP00000045141 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (273 aa) |
| | TLR9 | TIR domain-containing protein. (1027 aa) |
