STRINGSTRING
MYOZ2 MYOZ2 CAMTA1 CAMTA1 PPP3CC PPP3CC FHL2 FHL2 SPPL3 SPPL3 ENSOCUP00000046835 ENSOCUP00000046835 HOMER2 HOMER2 CHERP CHERP LOC100356734 LOC100356734 NFAT5 NFAT5 CMYA5 CMYA5 STIMATE STIMATE PRNP PRNP ATP2B4 ATP2B4 TNF TNF LMCD1 LMCD1 RCAN1 RCAN1 MTOR MTOR PLCG2 PLCG2 EFHB EFHB CHP1 CHP1 AKAP6 AKAP6 C10orf71 C10orf71 MAPK7 MAPK7 ERBB3 ERBB3 CIB1 CIB1 TBC1D10C TBC1D10C MYOZ1 MYOZ1 IGF1 IGF1 AKAP5 AKAP5 SLC9A1 SLC9A1 ACTN3 ACTN3 G1U4L1_RABIT G1U4L1_RABIT G1U7S6_RABIT G1U7S6_RABIT DYRK2 DYRK2 GSK3B GSK3B NRG1 NRG1 CHP2 CHP2 ENSOCUP00000029750 ENSOCUP00000029750
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYOZ2Myozenin 2. (282 aa)
CAMTA1Calmodulin binding transcription activator 1. (1616 aa)
PPP3CCSerine/threonine-protein phosphatase. (574 aa)
FHL2Four and a half LIM domains 2. (306 aa)
SPPL3Signal peptide peptidase like 3. (456 aa)
ENSOCUP00000046835Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (564 aa)
HOMER2Homer scaffold protein 2. (375 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (651 aa)
LOC100356734Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1283 aa)
NFAT5Nuclear factor of activated T cells 5. (1554 aa)
CMYA5Cardiomyopathy associated 5. (3683 aa)
STIMATEUncharacterized protein. (297 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (252 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
LMCD1LIM and cysteine rich domains 1. (365 aa)
RCAN1Regulator of calcineurin 1. (197 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
EFHBEF-hand domain family member B. (780 aa)
CHP1Calcineurin like EF-hand protein 1. (194 aa)
AKAP6A-kinase anchoring protein 6. (2318 aa)
C10orf71Chromosome 10 open reading frame 71. (1361 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (818 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1339 aa)
CIB1Uncharacterized protein. (143 aa)
TBC1D10CTBC1 domain family member 10C. (447 aa)
MYOZ1Uncharacterized protein. (310 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa)
AKAP5A-kinase anchoring protein 5. (403 aa)
SLC9A1Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (900 aa)
G1U4L1_RABITUncharacterized protein. (195 aa)
G1U7S6_RABITUncharacterized protein. (209 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (567 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
NRG1Neuregulin 1. (720 aa)
CHP2Calcineurin like EF-hand protein 2. (229 aa)
ENSOCUP00000029750Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (907 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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