STRINGSTRING
CASP9 CASP9 AXIN2 AXIN2 ENSOCUP00000045925 ENSOCUP00000045925 ENSOCUP00000044284 ENSOCUP00000044284 ENSOCUP00000041840 ENSOCUP00000041840 ENSOCUP00000042867 ENSOCUP00000042867 DDIT4 DDIT4 IGF1R IGF1R MSTN MSTN GJB2 GJB2 G1SV95_RABIT G1SV95_RABIT GDNF GDNF SMYD3 SMYD3 ERRFI1 ERRFI1 RPS6KB1 RPS6KB1 USP8 USP8 SERPINF1 SERPINF1 PCK2 PCK2 METTL21C METTL21C FBXO32 FBXO32 GHRHR GHRHR ENSOCUP00000037329 ENSOCUP00000037329 LOC103345451 LOC103345451 TFAP4 TFAP4 ENSOCUP00000027928 ENSOCUP00000027928 ASS1 ASS1 PCK1 PCK1 SRD5A1 SRD5A1 JAK2 JAK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASP9Caspase 9; Belongs to the peptidase C14A family. (466 aa)
AXIN2Axin 2. (816 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
ENSOCUP00000042867Uncharacterized protein. (340 aa)
DDIT4DNA damage inducible transcript 4. (229 aa)
IGF1RTyrosine-protein kinase receptor. (1464 aa)
MSTNMyostatin. (375 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
GDNFGlial cell derived neurotrophic factor. (159 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (459 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1; Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTO [...] (490 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1088 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
METTL21CMethyltransferase like 21C. (331 aa)
FBXO32F-box protein 32. (364 aa)
GHRHRUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (524 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
TFAP4Transcription factor AP-4. (585 aa)
ENSOCUP00000027928Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (88 aa)
ASS1Uncharacterized protein. (251 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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