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| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (958 aa) |
| | BNIP3 | BCL2 interacting protein 3. (218 aa) |
| | SLC24A2 | Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (665 aa) |
| | RYR2 | Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity). The calcium channel activity is modulated by formation of heterotetramers with RYR3; Belongs to t [...] (4965 aa) |
| | CALCA | Calcitonin related polypeptide alpha. (140 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (994 aa) |
| | MYH7B | Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa) |
| | PML | Promyelocytic leukemia. (860 aa) |
| | HPS1 | HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (703 aa) |
| | SMDT1 | Uncharacterized protein. (305 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | SLC39A6 | Solute carrier family 39 member 6. (730 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | MICU3 | Mitochondrial calcium uptake family member 3. (534 aa) |
| | KEL | Kell metallo-endopeptidase (Kell blood group). (732 aa) |
| | ENSOCUP00000045399 | Uncharacterized protein. (182 aa) |
| | CDH23 | Cadherin related 23. (3330 aa) |
| | TMBIM6 | Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (306 aa) |
| | LOC100356734 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1283 aa) |
| | ENSOCUP00000045925 | TGFb_propeptide domain-containing protein. (272 aa) |
| | CHRNA7 | Uncharacterized protein. (513 aa) |
| | CHERP | Calcium homeostasis endoplasmic reticulum protein. (651 aa) |
| | ENSOCUP00000046471 | XRCC1_N domain-containing protein. (405 aa) |
| | ENSOCUP00000046835 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (564 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (738 aa) |
| | TRPM8 | Transient receptor potential cation channel subfamily M member 8. (1171 aa) |
| | MCUR1 | Mitochondrial calcium uniporter regulator 1. (231 aa) |
| | SELENOK | Uncharacterized protein. (93 aa) |
| | ATP2B1 | Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa) |
| | ENSOCUP00000048888 | Uncharacterized protein. (249 aa) |
| | ATP2B3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1245 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1187 aa) |
| | RYR3 | Ryanodine receptor 3; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Plays a role in cellular calcium signaling. Contributes to cellular calcium ion homeostasis. Isoform 2 lacks a predicted transmembrane segment and does not form functional calcium channels by itself; however, it can form tetramers [...] (4876 aa) |
| | TGM2 | Transglutaminase 2. (845 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | ATP7B | ATPase copper transporting beta. (1465 aa) |
| | CALCB | Calcitonin related polypeptide beta. (174 aa) |
| | ENSOCUP00000041840 | TGFb_propeptide domain-containing protein. (219 aa) |
| | PTH1R | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (619 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1822 aa) |
| | RMDN2 | Uncharacterized protein. (547 aa) |
| | GRIA1 | Glutamate ionotropic receptor AMPA type subunit 1. (915 aa) |
| | ATP2C1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (949 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (549 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | SLC10A7 | Solute carrier family 10 member 7. (378 aa) |
| | STIM1 | Stromal interaction molecule 1. (789 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1111 aa) |
| | CSRP3 | Cysteine and glycine rich protein 3. (245 aa) |
| | RMDN3 | Regulator of microtubule dynamics 3. (493 aa) |
| | BCL2 | BH4_2 domain-containing protein. (389 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1074 aa) |
| | ANK2 | Ankyrin 2. (3805 aa) |
| | TUNAR | TCL1 upstream neural differentiation-associated RNA. (45 aa) |
| | ENSOCUP00000034581 | Uncharacterized protein. (151 aa) |
| | ENSOCUP00000034564 | Uncharacterized protein. (182 aa) |
| | CD40 | Uncharacterized protein. (494 aa) |
| | UMOD | Uromodulin. (794 aa) |
| | SLC8A1 | J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) |
| | MCUB | Mitochondrial calcium uniporter dominant negative beta subunit. (393 aa) |
| | SLC30A7 | Solute carrier family 30 member 7. (376 aa) |
| | TMCO1 | Transmembrane and coiled-coil domains 1. (217 aa) |
| | ENSOCUP00000032183 | Uncharacterized protein. (349 aa) |
| | ATP13A5 | Uncharacterized protein. (98 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | THADA | THADA armadillo repeat containing. (2155 aa) |
| | ENSOCUP00000030568 | Cation_ATPase_N domain-containing protein. (178 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2756 aa) |
| | LOC100359182 | Amino acid transporter. (665 aa) |
| | ENSOCUP00000029750 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (907 aa) |
| | STIM2 | Stromal interaction molecule 2. (831 aa) |
| | MICU1 | Mitochondrial calcium uptake 1. (566 aa) |
| | ENSOCUP00000028320 | Uncharacterized protein. (212 aa) |
| | SLC11A1 | Uncharacterized protein. (552 aa) |
| | U3KPA1_RABIT | ANF_receptor domain-containing protein. (237 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (210 aa) |
| | MICU2 | Mitochondrial calcium uptake 2. (397 aa) |
| | GPR3 | G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | RYR1 | Ryanodine receptor 1; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high- level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm (By similarity). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. [...] (4598 aa) |
| | TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (929 aa) |
| | P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) |
| | TRPC3 | Transient receptor potential cation channel subfamily C member 3. (991 aa) |
| | SLC39A13 | Solute carrier family 39 member 13. (367 aa) |
| | GRINA | Glutamate ionotropic receptor NMDA type subunit associated protein 1. (361 aa) |
| | TRPC2 | Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (879 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (145 aa) |
| | SYPL2 | Synaptophysin-like protein 2; Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes. (264 aa) |
| | SLC41A1 | Solute carrier family 41 member 1. (473 aa) |
| | TRPA1 | Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa) |
| | CCL14 | C-C motif chemokine ligand 14. (94 aa) |
| | FIS1 | Fission, mitochondrial 1. (207 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | PACS2 | Phosphofurin acidic cluster sorting protein 2. (537 aa) |
| | SLC24A1 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (470 aa) |
| | VDR | Vitamin D receptor. (368 aa) |
| | MAIP1 | Uncharacterized protein. (292 aa) |
| | SLC39A10 | Solute carrier family 39 member 10. (832 aa) |
| | TRPC1 | Short transient receptor potential channel 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Seems to be also activated by intracellular calcium store depletion; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. (793 aa) |
| | GCM2 | Glial cells missing transcription factor 2. (500 aa) |
| | MT4 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa) |
| | SLC37A4 | Solute carrier family 37 member 4. (451 aa) |
| | SLC30A9 | Solute carrier family 30 member 9. (615 aa) |
| | P2RY4 | Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (416 aa) |
| | RAP1GDS1 | Rap1 GTPase-GDP dissociation stimulator 1. (605 aa) |
| | VAPB | VAMP associated protein B and C. (259 aa) |
| | HTR2C | 5-hydroxytryptamine receptor 2C. (453 aa) |
| | ATP13A4 | Cation_ATPase_N domain-containing protein. (615 aa) |
| | CALB2 | Calbindin 2. (271 aa) |
| | SLC24A4 | Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (613 aa) |
| | MCU | Mitochondrial calcium uniporter. (350 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | SCGN | Secretagogin, EF-hand calcium binding protein. (276 aa) |
| | LOC100346816 | Letm1 RBD domain-containing protein. (751 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation (By similarity). (52 aa) |
| | TMEM165 | GDT1 family protein. (313 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (202 aa) |
| | TMTC4 | Transmembrane O-mannosyltransferase targeting cadherins 4. (762 aa) |
| | SLC24A5 | Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (507 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (988 aa) |
| | SLC30A1 | Solute carrier family 30 member 1. (334 aa) |
| | TRPC4 | Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa) |
| | PDZD8 | PDZ domain containing 8. (1150 aa) |
| | G1T1C8_RABIT | Uncharacterized protein. (114 aa) |
| | FKBP1B | Peptidyl-prolyl cis-trans isomerase FKBP1B; Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (96 aa) |
| | CASQ2 | Calsequestrin-2; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. (486 aa) |
| | APP | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa) |
| | SLC30A5 | Solute carrier family 30 member 5. (767 aa) |
| | DISC1 | DISC1 scaffold protein. (859 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (974 aa) |
| | IMMT | MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (758 aa) |
| | NPTN | Neuroplastin. (367 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (469 aa) |
| | TMEM178A | Transmembrane protein 178A. (297 aa) |
| | SLC24A3 | Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (647 aa) |
| | SLC39A14 | Solute carrier family 39 member 14. (611 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (369 aa) |
| | G1SV95_RABIT | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | DHRS7C | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa) |
| | HCRTR2 | Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa) |
| | GRM1 | Glutamate metabotropic receptor 1. (1203 aa) |
| | XK | XK-related protein. (444 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | STOML2 | Stomatin like 2. (356 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | CALB1 | Cerebellar calbindin. (261 aa) |
| | HCRTR1 | Hypocretin receptor 1. (416 aa) |
| | STC1 | Stanniocalcin 1. (247 aa) |
| | PTH | Parathyroid hormone. (131 aa) |
| | ANXA6 | Annexin. (913 aa) |
| | HEXB | Beta-hexosaminidase. (532 aa) |
| | TRPC7 | Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (861 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | CCDC47 | Coiled-coil domain containing 47. (483 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (679 aa) |
| | SLC35G1 | Solute carrier family 35 member G1. (356 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (3985 aa) |
| | SLC39A8 | Solute carrier family 39 member 8. (437 aa) |
| | SV2A | Synaptic vesicle glycoprotein 2A. (742 aa) |
| | GRIK2 | Glutamate ionotropic receptor kainate type subunit 2. (908 aa) |
| | SLC8B1 | Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (528 aa) |
| | CCR1 | Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | SLC30A10 | Solute carrier family 30 member 10. (479 aa) |
| | C19orf12 | Chromosome 19 open reading frame 12. (142 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
