STRINGSTRING
ITPRIP ITPRIP CIB1 CIB1 DAPK1 DAPK1 ENSOCUP00000046773 ENSOCUP00000046773 ENSOCUP00000045925 ENSOCUP00000045925 ENSOCUP00000044284 ENSOCUP00000044284 EYA2 EYA2 SGPP1 SGPP1 ACVR1B ACVR1B ZDHHC3 ZDHHC3 IL12A IL12A TNFSF12 TNFSF12 ENSOCUP00000037329 ENSOCUP00000037329 IL7 IL7 DDX47 DDX47 INHBA INHBA PDIA3 PDIA3 CASP8AP2 CASP8AP2 ITGAV ITGAV ENSOCUP00000040918 ENSOCUP00000040918 ENSOCUP00000041840 ENSOCUP00000041840 JAK2 JAK2 DELE1 DELE1 ERBB3 ERBB3 TLR3 TLR3 CASP10 CASP10 TRADD TRADD BAK1 BAK1 SMAD3 SMAD3 ENSOCUP00000029917 ENSOCUP00000029917 CTTN CTTN LOC103345451 LOC103345451 KITLG KITLG FAS FAS PDPK1 PDPK1 CASP2 CASP2 PML PML WWOX WWOX KRT18 KRT18 PARP2 PARP2 GSK3A GSK3A FASLG FASLG BOK BOK BCL2L2 BCL2L2 STK4 STK4 BCL2L1 BCL2L1 CD70 CD70 GSK3B GSK3B HIPK1 HIPK1 G0S2 G0S2 STK3 STK3 MLLT11 MLLT11 PIK3R1 PIK3R1 TGFB2 TGFB2 BAX BAX DEDD2 DEDD2 TNF TNF GABARAP GABARAP G1SSE7_RABIT G1SSE7_RABIT BCL2L11 BCL2L11 CX3CL1 CX3CL1 CTNNA1 CTNNA1 CD27 CD27 G1SV95_RABIT G1SV95_RABIT FGF10 FGF10 RB1CC1 RB1CC1 NF1 NF1 IL1A IL1A P2RX7 P2RX7 EYA1 EYA1 RNF41 RNF41 IL2 IL2 DAXX DAXX BAG3 BAG3 RIPK1 RIPK1 BCL2L10 BCL2L10 MCL1 MCL1 BLOC1S2 BLOC1S2 SKIL SKIL DAB2IP DAB2IP IL33 IL33 SORT1 SORT1 TNFRSF1B TNFRSF1B BID BID BCL2 BCL2 ITPRIPL2 ITPRIPL2 LOC100008885 LOC100008885
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITPRIPInositol 1,4,5-trisphosphate receptor interacting protein. (503 aa)
CIB1Uncharacterized protein. (143 aa)
DAPK1Death associated protein kinase 1. (1493 aa)
ENSOCUP00000046773Protein kinase domain-containing protein. (249 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa)
SGPP1acidPPc domain-containing protein. (558 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (474 aa)
ZDHHC3Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (400 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (233 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (248 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
DDX47DEAD-box helicase 47; Belongs to the DEAD box helicase family. (597 aa)
INHBAInhibin subunit beta A. (424 aa)
PDIA3Protein disulfide-isomerase. (502 aa)
CASP8AP2Caspase 8 associated protein 2. (1950 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
ENSOCUP00000040918Protein kinase domain-containing protein. (81 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
DELE1DAP3 binding cell death enhancer 1. (512 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1339 aa)
TLR3TIR domain-containing protein; Belongs to the Toll-like receptor family. (867 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (469 aa)
TRADDTNFRSF1A associated via death domain. (447 aa)
BAK1BCL2 antagonist/killer 1. (210 aa)
SMAD3SMAD family member 3. (230 aa)
ENSOCUP00000029917Uncharacterized protein. (169 aa)
CTTNCortactin. (653 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (276 aa)
FASUncharacterized protein. (484 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (451 aa)
PMLPromyelocytic leukemia. (860 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
KRT18IF rod domain-containing protein; Belongs to the intermediate filament family. (431 aa)
PARP2Poly [ADP-ribose] polymerase. (566 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (259 aa)
BOKBCL2 family apoptosis regulator BOK. (145 aa)
BCL2L2BCL2 like 2. (193 aa)
STK4Uncharacterized protein. (487 aa)
BCL2L1Bcl-X. (233 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (297 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
HIPK1Homeodomain interacting protein kinase 1. (1447 aa)
G0S2G0/G1 switch 2. (98 aa)
STK3Serine/threonine kinase 3. (491 aa)
MLLT11AF1q. (90 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
DEDD2Death effector domain containing 2. (431 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family. (117 aa)
G1SSE7_RABITUncharacterized protein; Belongs to the peptidase C14A family. (306 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (194 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (404 aa)
CTNNA1Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] (993 aa)
CD27CD27 molecule. (260 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
RB1CC1RB1 inducible coiled-coil 1. (1606 aa)
NF1Neurofibromin 1. (2841 aa)
IL1AInterleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (267 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (622 aa)
RNF41Ring finger protein 41. (317 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (153 aa)
DAXXDeath domain associated protein. (740 aa)
BAG3BCL2 associated athanogene 3. (805 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (670 aa)
BCL2L10Uncharacterized protein. (187 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (352 aa)
BLOC1S2Biogenesis of lysosomal organelles complex 1 subunit 2. (142 aa)
SKILSKI like proto-oncogene. (683 aa)
DAB2IPDAB2 interacting protein. (1178 aa)
IL33Uncharacterized protein. (142 aa)
SORT1Sortilin. (800 aa)
TNFRSF1BTNF receptor superfamily member 1B. (425 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (210 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
ITPRIPL2ITPRIP like 2. (519 aa)
LOC100008885IF rod domain-containing protein; Belongs to the intermediate filament family. (418 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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