STRINGSTRING
LSM8 LSM8 PRPF8 PRPF8 SNRPB2 SNRPB2 PRPF31 PRPF31 CD2BP2 CD2BP2 ZMAT2 ZMAT2 SNRPD3 SNRPD3 PRPF4 PRPF4 SF3A3 SF3A3 PRPF39 PRPF39 SF3B5 SF3B5 TXNL4B TXNL4B C19orf54 C19orf54 SNRNP200 SNRNP200 SF3B2 SF3B2 SNRPF SNRPF LOC100345430 LOC100345430 SNRPG SNRPG PPIH PPIH PRPF3 PRPF3 RBMX2 RBMX2 G1T572_RABIT G1T572_RABIT SNRPB SNRPB SNRNP40 SNRNP40 SNRNP70 SNRNP70 LSM6 LSM6 G1TGF3_RABIT G1TGF3_RABIT SNRPD2 SNRPD2 SART1 SART1 SF3B6 SF3B6 SNRPA SNRPA G1TPR7_RABIT G1TPR7_RABIT SNRPD1 SNRPD1 SNRPC-2 SNRPC-2 SF3B1 SF3B1 ENSOCUP00000021369 ENSOCUP00000021369 SNRNP27 SNRNP27 G1TXZ2_RABIT G1TXZ2_RABIT SNRPC SNRPC SNU13 SNU13 SNRPC-3 SNRPC-3 DDX39B DDX39B G1U7T7_RABIT G1U7T7_RABIT LSM5 LSM5 DDX23 DDX23 ENSOCUP00000027407 ENSOCUP00000027407 SF3A1 SF3A1 PRPF6 PRPF6 ENSOCUP00000028949 ENSOCUP00000028949 USP39 USP39 SNRPC-4 SNRPC-4 ENSOCUP00000031801 ENSOCUP00000031801 SNRPD2-2 SNRPD2-2 ENSOCUP00000032874 ENSOCUP00000032874 LUC7L3 LUC7L3 ENSOCUP00000033150 ENSOCUP00000033150 SNRPD2-3 SNRPD2-3 TXNL4A TXNL4A ENSOCUP00000040270 ENSOCUP00000040270 LSM2 LSM2 ENSOCUP00000042353 ENSOCUP00000042353 PHF5A PHF5A SNRPE SNRPE PRPF40A PRPF40A EFTUD2 EFTUD2 PRPF40B PRPF40B ENSOCUP00000044535 ENSOCUP00000044535 RBM42 RBM42 ENSOCUP00000046384 ENSOCUP00000046384 ENSOCUP00000046496 ENSOCUP00000046496 LUC7L LUC7L ENSOCUP00000047469 ENSOCUP00000047469 ENSOCUP00000048230 ENSOCUP00000048230 PRPF18 PRPF18 FMC1-LUC7L2 FMC1-LUC7L2 SNRPC-5 SNRPC-5 SF3B1-2 SF3B1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
PRPF31Pre-mRNA processing factor 31. (462 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (340 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
PRPF4Pre-mRNA processing factor 4. (522 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
PRPF39Pre-mRNA processing factor 39. (669 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
C19orf54Chromosome 19 open reading frame 54. (367 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2135 aa)
SF3B2Splicing factor 3b subunit 2. (869 aa)
SNRPFSmall nuclear ribonucleoprotein polypeptide F. (86 aa)
LOC100345430U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
PRPF3Pre-mRNA processing factor 3. (683 aa)
RBMX2RNA binding motif protein X-linked 2. (329 aa)
G1T572_RABITRibosomal_L7Ae domain-containing protein. (73 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (400 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (561 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
G1TGF3_RABITSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
SART1Uncharacterized protein. (160 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (265 aa)
G1TPR7_RABITSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (155 aa)
SF3B1SF3b1 domain-containing protein. (1120 aa)
ENSOCUP00000021369annotation not available (102 aa)
SNRNP27SNRNP27 domain-containing protein. (155 aa)
G1TXZ2_RABITSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (178 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
SNRPC-3U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
DDX39BDExD-box helicase 39B. (427 aa)
G1U7T7_RABITSmall nuclear ribonucleoprotein-associated protein. (218 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
DDX23DEAD-box helicase 23. (825 aa)
ENSOCUP00000027407Sm domain-containing protein. (65 aa)
SF3A1Splicing factor 3a subunit 1. (917 aa)
PRPF6Pre-mRNA processing factor 6. (1038 aa)
ENSOCUP00000028949Ribosomal_L7Ae domain-containing protein. (73 aa)
USP39Ubiquitin specific peptidase 39. (565 aa)
SNRPC-4U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (160 aa)
ENSOCUP00000031801SNRNP27 domain-containing protein. (155 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (112 aa)
ENSOCUP00000032874Uncharacterized protein. (53 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (496 aa)
ENSOCUP00000033150Uncharacterized protein. (70 aa)
SNRPD2-3Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (69 aa)
TXNL4AThioredoxin like 4A. (97 aa)
ENSOCUP00000040270Uncharacterized protein. (120 aa)
LSM2Sm domain-containing protein. (215 aa)
ENSOCUP00000042353Uncharacterized protein. (59 aa)
PHF5APHD finger protein 5A. (173 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
PRPF40AUncharacterized protein. (608 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (1021 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (1051 aa)
ENSOCUP00000044535Sm domain-containing protein. (48 aa)
RBM42RNA binding motif protein 42. (475 aa)
ENSOCUP00000046384Sm domain-containing protein. (123 aa)
ENSOCUP00000046496Uncharacterized protein. (126 aa)
LUC7LLUC7 like. (361 aa)
ENSOCUP00000047469Uncharacterized protein. (57 aa)
ENSOCUP00000048230Uncharacterized protein. (215 aa)
PRPF18SFM domain-containing protein. (415 aa)
FMC1-LUC7L2FMC1-LUC7L2 readthrough. (475 aa)
SNRPC-5U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (170 aa)
SF3B1-2Uncharacterized protein. (154 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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