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| PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa) | ||||
| HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (356 aa) | ||||
| PAWR | Pro-apoptotic WT1 regulator. (339 aa) | ||||
| SLC7A2 | Solute carrier family 7 member 2. (757 aa) | ||||
| KCNK9 | Potassium two pore domain channel subfamily K member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (477 aa) | ||||
| CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2141 aa) | ||||
| ENSOCUP00000031621 | Uncharacterized protein. (1225 aa) | ||||
| LOC100359182 | Amino acid transporter. (665 aa) | ||||
| CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) | ||||
| ATP1B2 | Sodium/potassium-transporting ATPase subunit beta-2; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known (By similarity). (290 aa) | ||||
| SLC12A5 | Solute carrier family 12 member 5. (1015 aa) | ||||
| KCNJ5 | Potassium voltage-gated channel subfamily J member 5. (463 aa) | ||||
| KCNJ3 | Potassium voltage-gated channel subfamily J member 3. (501 aa) | ||||
| SLC19A1 | Solute carrier family 19 member 1. (557 aa) | ||||
| SLC12A2 | Solute carrier family 12 member 2. (1127 aa) | ||||
| ENSOCUP00000030127 | Uncharacterized protein. (265 aa) | ||||
| KCNJ15 | Potassium voltage-gated channel subfamily J member 15. (415 aa) | ||||
| SLC6A1 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (254 aa) | ||||
| SLC1A1 | Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine (By similarity). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspar [...] (524 aa) | ||||
| SLC1A3 | Amino acid transporter. (542 aa) | ||||
| LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (769 aa) | ||||
| SLC3A2 | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...] (571 aa) | ||||
| TRPV5 | Transient receptor potential cation channel subfamily V member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric con [...] (730 aa) | ||||
| SLC46A1 | MFS domain-containing protein. (473 aa) | ||||
| KCNJ8 | Inward rectifier potassium channel 6.1. (424 aa) | ||||
| ARL6IP5 | PRA1 family protein. (188 aa) | ||||
| SCNN1B | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] (641 aa) | ||||
| FAM155B | Family with sequence similarity 155 member B. (466 aa) | ||||
| SLC39A14 | Solute carrier family 39 member 14. (611 aa) | ||||
| KCNJ14 | Potassium voltage-gated channel subfamily J member 14. (434 aa) | ||||
| SLC16A2 | Solute carrier family 16 member 2. (539 aa) | ||||
| SLC15A2 | Solute carrier family 15 member 2; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity). Can also transport the aminocephalosporin antibiotic cefadroxil ; Belongs to the PTR2/POT transporter (TC 2.A.17) family. (729 aa) | ||||
| SLC6A6 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (675 aa) | ||||
| SLC24A2 | Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (665 aa) | ||||
| SLC6A5 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (797 aa) | ||||
| SLC1A2 | Amino acid transporter. (579 aa) | ||||
| SLC39A6 | Solute carrier family 39 member 6. (730 aa) | ||||
| ATP1B3 | Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (274 aa) | ||||
| SLC12A6 | Solute carrier family 12 member 6. (1197 aa) | ||||
| SLC12A4 | Solute carrier family 12 member 4; Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia; Belongs to the SLC12A transporter family. (1085 aa) | ||||
| TRPV6 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (699 aa) | ||||
| KCNJ13 | Potassium voltage-gated channel subfamily J member 13. (360 aa) | ||||
| KCNJ16 | Potassium voltage-gated channel subfamily J member 16. (419 aa) | ||||
| ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1027 aa) | ||||
| SLC7A11 | Solute carrier family 7 member 11. (502 aa) | ||||
| SLC9A1 | Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa) | ||||
| IRK2 | Uncharacterized protein. (398 aa) | ||||
| FOLR2 | Folate_rec domain-containing protein. (305 aa) | ||||
| CACNA2D1 | Voltage-dependent calcium channel subunit alpha-2/delta-1; The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation- contraction coupling. (1061 aa) | ||||
| FAM155A | Family with sequence similarity 155 member A. (296 aa) | ||||
| SLC9A9 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (644 aa) | ||||
| KCNJ9 | Potassium voltage-gated channel subfamily J member 9. (283 aa) | ||||
| SLC36A1 | Aa_trans domain-containing protein. (501 aa) | ||||
| SLC39A5 | Solute carrier family 39 member 5. (549 aa) | ||||
| SLC6A20 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (592 aa) | ||||
| ENSOCUP00000032183 | Uncharacterized protein. (349 aa) | ||||
| GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (515 aa) | ||||
| TSPO2 | Translocator protein 2. (205 aa) | ||||
| CLN8 | CLN8 transmembrane ER and ERGIC protein. (288 aa) | ||||
| KCNE2 | Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa) | ||||
| ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (By similarity). May contribute to blood-heart barrier properties of endocardial endothelium and may control cardiac performance via endothelial Na(+)/H(+) exchange. (956 aa) | ||||
| SLC15A4 | Solute carrier family 15 member 4. (399 aa) | ||||
| SLC27A5 | Solute carrier family 27 member 5. (680 aa) | ||||
| ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1019 aa) | ||||
| SLC8A1 | J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) | ||||
| STEAP2 | Uncharacterized protein. (470 aa) | ||||
| SLC5A6 | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (680 aa) | ||||
| LRRC8E | Leucine rich repeat containing 8 VRAC subunit E. (827 aa) | ||||
| SLC12A3 | Uncharacterized protein. (1027 aa) | ||||
| SLC39A10 | Solute carrier family 39 member 10. (832 aa) | ||||
| U3KNC9_RABIT | Uncharacterized protein. (382 aa) | ||||
| SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (512 aa) | ||||
| CNGA3 | Cyclic nucleotide gated channel subunit alpha 3. (691 aa) | ||||
| SLC9C1 | Solute carrier family 9 member C1. (1151 aa) | ||||
| SLC9A5 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (895 aa) | ||||
| KCNJ4 | Potassium voltage-gated channel subfamily J member 4. (442 aa) | ||||
| KCNJ2 | Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...] (427 aa) | ||||
| SLC7A3 | Solute carrier family 7 member 3. (594 aa) | ||||
| LRRC8C | Leucine rich repeat containing 8 VRAC subunit C. (803 aa) | ||||
| G1T017_RABIT | Amino acid transporter. (234 aa) | ||||
| LRP2 | Uncharacterized protein. (2726 aa) | ||||
| KCNJ10 | Potassium voltage-gated channel subfamily J member 10. (564 aa) | ||||
| SLC15A1 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. (700 aa) | ||||
| TRPV3 | Transient receptor potential cation channel subfamily V member 3. (768 aa) | ||||
| TRPV1 | Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Ac [...] (842 aa) | ||||
| SLC9A6 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa) | ||||
| SLC1A6 | Amino acid transporter. (564 aa) | ||||
| KCNJ1 | Potassium voltage-gated channel subfamily J member 1. (391 aa) | ||||
| STEAP3 | STEAP3 metalloreductase. (498 aa) | ||||
| HCN4 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli. (913 aa) | ||||
| SLC12A8 | Solute carrier family 12 member 8. (710 aa) | ||||
| SCNN1A | Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. (491 aa) | ||||
| KCNH2 | Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1108 aa) | ||||
| G1TNN7_RABIT | Uncharacterized protein. (571 aa) | ||||
| SLC39A8 | Solute carrier family 39 member 8. (437 aa) | ||||
| SLC9A7 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (726 aa) | ||||
| TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (679 aa) | ||||
| G1SLQ5_RABIT | AA_permease_C domain-containing protein. (635 aa) | ||||
| CACNA1F | Calcium voltage-gated channel subunit alpha1 F. (1734 aa) | ||||
| TRPV2 | Transient receptor potential cation channel subfamily V member 2. (817 aa) | ||||
| SLC9A4 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (803 aa) | ||||
| SLC7A1 | Solute carrier family 7 member 1. (646 aa) | ||||
| SLC9A3 | Sodium/hydrogen exchanger 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. (813 aa) | ||||
| SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (958 aa) | ||||
| ATP1A3 | Sodium/potassium-transporting ATPase subunit alpha. (964 aa) | ||||
| SLC7A8 | Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administe [...] (535 aa) | ||||
| SLC6A9 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (652 aa) | ||||
| SLC2A10 | Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (483 aa) | ||||
| SLC5A1 | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. (662 aa) | ||||
| SLC15A3 | Solute carrier family 15 member 3. (575 aa) | ||||
| SLC24A4 | Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (613 aa) | ||||
| SLC9C2 | Solute carrier family 9 member C2 (putative). (1113 aa) | ||||
| SLC6A14 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (637 aa) | ||||