node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAM22 | CACNG2 | ENSOCUP00000013276 | ENSOCUP00000021577 | ADAM metallopeptidase domain 22. | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.671 |
ADAM22 | CACNG3 | ENSOCUP00000013276 | ENSOCUP00000003454 | ADAM metallopeptidase domain 22. | Calcium voltage-gated channel auxiliary subunit gamma 3. | 0.445 |
ADAM22 | CACNG4 | ENSOCUP00000013276 | ENSOCUP00000012219 | ADAM metallopeptidase domain 22. | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.431 |
ADAM22 | LRFN2 | ENSOCUP00000013276 | ENSOCUP00000007605 | ADAM metallopeptidase domain 22. | Leucine rich repeat and fibronectin type III domain containing 2. | 0.524 |
CACNG2 | ADAM22 | ENSOCUP00000021577 | ENSOCUP00000013276 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | ADAM metallopeptidase domain 22. | 0.671 |
CACNG2 | CACNG3 | ENSOCUP00000021577 | ENSOCUP00000003454 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Calcium voltage-gated channel auxiliary subunit gamma 3. | 0.511 |
CACNG2 | CACNG4 | ENSOCUP00000021577 | ENSOCUP00000012219 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.562 |
CACNG2 | CACNG7 | ENSOCUP00000021577 | ENSOCUP00000024917 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.572 |
CACNG2 | GRIA1 | ENSOCUP00000021577 | ENSOCUP00000040130 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor AMPA type subunit 1. | 0.963 |
CACNG2 | GRIN2D | ENSOCUP00000021577 | ENSOCUP00000018934 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 2D. | 0.403 |
CACNG2 | GRIN3A | ENSOCUP00000021577 | ENSOCUP00000023394 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 3A. | 0.664 |
CACNG2 | SHISA9 | ENSOCUP00000021577 | ENSOCUP00000024362 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Shisa family member 9. | 0.663 |
CACNG3 | ADAM22 | ENSOCUP00000003454 | ENSOCUP00000013276 | Calcium voltage-gated channel auxiliary subunit gamma 3. | ADAM metallopeptidase domain 22. | 0.445 |
CACNG3 | CACNG2 | ENSOCUP00000003454 | ENSOCUP00000021577 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.511 |
CACNG3 | CACNG4 | ENSOCUP00000003454 | ENSOCUP00000012219 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.486 |
CACNG3 | GRIA1 | ENSOCUP00000003454 | ENSOCUP00000040130 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Glutamate ionotropic receptor AMPA type subunit 1. | 0.579 |
CACNG3 | GRIN2D | ENSOCUP00000003454 | ENSOCUP00000018934 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Glutamate ionotropic receptor NMDA type subunit 2D. | 0.412 |
CACNG3 | GRIN3A | ENSOCUP00000003454 | ENSOCUP00000023394 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Glutamate ionotropic receptor NMDA type subunit 3A. | 0.458 |
CACNG3 | SHISA9 | ENSOCUP00000003454 | ENSOCUP00000024362 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Shisa family member 9. | 0.472 |
CACNG4 | ADAM22 | ENSOCUP00000012219 | ENSOCUP00000013276 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | ADAM metallopeptidase domain 22. | 0.431 |