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RUVBL1 RUVBL1 RUVBL2 RUVBL2 SPAG1 SPAG1 ZMYND10 ZMYND10 WDR92 WDR92 DNAI2 DNAI2 HSP90AB1 HSP90AB1 DNAAF2 DNAAF2 DNAAF4 DNAAF4 DNALI1 DNALI1 WDR78 WDR78 C16orf71 C16orf71 STIP1 STIP1 ENSOCUP00000045443 ENSOCUP00000045443
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (485 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
SPAG1Sperm associated antigen 1. (813 aa)
ZMYND10Uncharacterized protein. (210 aa)
WDR92WD repeat domain 92. (357 aa)
DNAI2Dynein axonemal intermediate chain 2. (604 aa)
HSP90AB1Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (726 aa)
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (790 aa)
DNAAF4Dynein axonemal assembly factor 4. (419 aa)
DNALI1Dynein axonemal light intermediate chain 1. (299 aa)
WDR78WD repeat domain 78. (810 aa)
C16orf71Chromosome 16 open reading frame 71. (514 aa)
STIP1Stress induced phosphoprotein 1. (589 aa)
ENSOCUP00000045443Uncharacterized protein. (209 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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