(22 nodes) Positive regulation of cytokine production involved in inflammatory response network (Oryctolagus cuniculus)

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Predicted Interactions

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Your Input:
	CD6	CD6 molecule. (683 aa)
	IL17RC	Interleukin 17 receptor C. (770 aa)
	TNF	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
	ANKRD42	Ankyrin repeat domain 42. (521 aa)
	IL17F	Interleukin 17F. (163 aa)
	PLA2G3	Phospholipase A2 group III. (636 aa)
	IL17A	Interleukin 17A. (153 aa)
	TLR4	TIR domain-containing protein; Belongs to the Toll-like receptor family. (839 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
	LOC100349257	GB1/RHD3-type G domain-containing protein. (624 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	NOD2	Nucleotide oligomerization domain 2 protein. (1013 aa)
	CLEC7A	C-type lectin domain containing 7A. (247 aa)
	IL17RA	Interleukin 17 receptor A. (860 aa)
	G1U0P1_RABIT	Uncharacterized protein. (209 aa)
	LOC100346209	GB1/RHD3-type G domain-containing protein. (645 aa)
	ENSOCUP00000027355	ANK_REP_REGION domain-containing protein. (78 aa)
	GPSM3	G protein signaling modulator 3. (160 aa)
	ENSOCUP00000032533	ANK_REP_REGION domain-containing protein. (78 aa)
	MYD88	Uncharacterized protein. (476 aa)
	ENSOCUP00000035366	IL17R_fnIII_D1 domain-containing protein. (331 aa)
	HIF1A	Uncharacterized protein. (851 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLEC7A	MYD88	ENSOCUP00000014442	ENSOCUP00000034296	C-type lectin domain containing 7A.	Uncharacterized protein.	0.469
CLEC7A	TLR4	ENSOCUP00000014442	ENSOCUP00000001909	C-type lectin domain containing 7A.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.573
ENSOCUP00000035366	IL17A	ENSOCUP00000035366	ENSOCUP00000003688	IL17R_fnIII_D1 domain-containing protein.	Interleukin 17A.	0.885
ENSOCUP00000035366	IL17F	ENSOCUP00000035366	ENSOCUP00000003689	IL17R_fnIII_D1 domain-containing protein.	Interleukin 17F.	0.818
ENSOCUP00000035366	IL17RC	ENSOCUP00000035366	ENSOCUP00000047419	IL17R_fnIII_D1 domain-containing protein.	Interleukin 17 receptor C.	0.702
G1U0P1_RABIT	IL17A	ENSOCUP00000022922	ENSOCUP00000003688	Uncharacterized protein.	Interleukin 17A.	0.401
G1U0P1_RABIT	STAT3	ENSOCUP00000022922	ENSOCUP00000009494	Uncharacterized protein.	Signal transducer and activator of transcription.	0.600
HIF1A	STAT3	ENSOCUP00000041090	ENSOCUP00000009494	Uncharacterized protein.	Signal transducer and activator of transcription.	0.945
HIF1A	TLR4	ENSOCUP00000041090	ENSOCUP00000001909	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.569
IL17A	ENSOCUP00000035366	ENSOCUP00000003688	ENSOCUP00000035366	Interleukin 17A.	IL17R_fnIII_D1 domain-containing protein.	0.885
IL17A	G1U0P1_RABIT	ENSOCUP00000003688	ENSOCUP00000022922	Interleukin 17A.	Uncharacterized protein.	0.401
IL17A	IL17F	ENSOCUP00000003688	ENSOCUP00000003689	Interleukin 17A.	Interleukin 17F.	0.993
IL17A	IL17RA	ENSOCUP00000003688	ENSOCUP00000022474	Interleukin 17A.	Interleukin 17 receptor A.	0.999
IL17A	IL17RC	ENSOCUP00000003688	ENSOCUP00000047419	Interleukin 17A.	Interleukin 17 receptor C.	0.988
IL17A	MYD88	ENSOCUP00000003688	ENSOCUP00000034296	Interleukin 17A.	Uncharacterized protein.	0.662
IL17A	NOD2	ENSOCUP00000003688	ENSOCUP00000011052	Interleukin 17A.	Nucleotide oligomerization domain 2 protein.	0.410
IL17A	STAT3	ENSOCUP00000003688	ENSOCUP00000009494	Interleukin 17A.	Signal transducer and activator of transcription.	0.819
IL17A	TLR4	ENSOCUP00000003688	ENSOCUP00000001909	Interleukin 17A.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.734
IL17A	TNF	ENSOCUP00000003688	ENSOCUP00000005787	Interleukin 17A.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.421
IL17F	ENSOCUP00000035366	ENSOCUP00000003689	ENSOCUP00000035366	Interleukin 17F.	IL17R_fnIII_D1 domain-containing protein.	0.818