STRINGSTRING
ENSOCUP00000044284 ENSOCUP00000044284 ENSOCUP00000041840 ENSOCUP00000041840 ENSOCUP00000040784 ENSOCUP00000040784 ENSOCUP00000037329 ENSOCUP00000037329 LOC103345451 LOC103345451 G1U940_RABIT G1U940_RABIT G1U0P1_RABIT G1U0P1_RABIT G1TJP7_RABIT G1TJP7_RABIT LIN28B LIN28B ZC3H10 ZC3H10 ZMPSTE24 ZMPSTE24 STAT3 STAT3 ZC3H12A ZC3H12A NCOR1 NCOR1 G1SV95_RABIT G1SV95_RABIT TNF TNF ESR1 ESR1 BCDIN3D BCDIN3D TP53 TP53 ENSOCUP00000045925 ENSOCUP00000045925 PPP3CA PPP3CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
ENSOCUP00000040784Uncharacterized protein. (227 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
G1U940_RABITCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa)
G1U0P1_RABITUncharacterized protein. (209 aa)
G1TJP7_RABITSANT domain-containing protein. (1611 aa)
LIN28BLin-28 homolog B. (258 aa)
ZC3H10Zinc finger CCCH-type containing 10. (436 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (580 aa)
NCOR1Nuclear receptor corepressor 1. (2374 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (598 aa)
BCDIN3DBCDIN3 domain containing RNA methyltransferase. (351 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
PPP3CASerine/threonine-protein phosphatase. (695 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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