17 items (Oryctolagus cuniculus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
	ENSOCUP00000041840	TGFb_propeptide domain-containing protein. (219 aa)
	ENSOCUP00000041421	CCHC-type domain-containing protein. (189 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	G1U940_RABIT	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (178 aa)
	ENSOCUP00000023367	annotation not available (209 aa)
	G1U0P1_RABIT	Uncharacterized protein. (209 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (670 aa)
	BMP4	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
	EGFR	Receptor protein-tyrosine kinase. (1193 aa)
	TRUB1	TruB pseudouridine synthase family member 1. (346 aa)
	G1SV95_RABIT	Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa)
	LOC100357100	CCHC-type domain-containing protein. (209 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)
	ENSOCUP00000045925	TGFb_propeptide domain-containing protein. (272 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	EGFR	ENSOCUP00000009545	ENSOCUP00000009041	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Receptor protein-tyrosine kinase.	0.465
BMP4	ENSOCUP00000023367	ENSOCUP00000009545	ENSOCUP00000023367	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	annotation not available	0.487
BMP4	ENSOCUP00000037329	ENSOCUP00000009545	ENSOCUP00000037329	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	TGFb_propeptide domain-containing protein.	0.612
BMP4	ENSOCUP00000044284	ENSOCUP00000009545	ENSOCUP00000044284	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	TGFb_propeptide domain-containing protein.	0.612
BMP4	LOC100357100	ENSOCUP00000009545	ENSOCUP00000000262	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	CCHC-type domain-containing protein.	0.487
BMP4	LOC103345451	ENSOCUP00000009545	ENSOCUP00000031740	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	TGFb_propeptide domain-containing protein.	0.612
DDX5	G1U940_RABIT	ENSOCUP00000043262	ENSOCUP00000025959	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.681
DDX5	TP53	ENSOCUP00000043262	ENSOCUP00000000989	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.725
DDX5	TRUB1	ENSOCUP00000043262	ENSOCUP00000008156	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	TruB pseudouridine synthase family member 1.	0.552
EGFR	BMP4	ENSOCUP00000009041	ENSOCUP00000009545	Receptor protein-tyrosine kinase.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.465
EGFR	ENSOCUP00000037329	ENSOCUP00000009041	ENSOCUP00000037329	Receptor protein-tyrosine kinase.	TGFb_propeptide domain-containing protein.	0.580
EGFR	ENSOCUP00000044284	ENSOCUP00000009041	ENSOCUP00000044284	Receptor protein-tyrosine kinase.	TGFb_propeptide domain-containing protein.	0.580
EGFR	LOC103345451	ENSOCUP00000009041	ENSOCUP00000031740	Receptor protein-tyrosine kinase.	TGFb_propeptide domain-containing protein.	0.580
EGFR	TP53	ENSOCUP00000009041	ENSOCUP00000000989	Receptor protein-tyrosine kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.871
ENSOCUP00000023367	BMP4	ENSOCUP00000023367	ENSOCUP00000009545	annotation not available	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.487
ENSOCUP00000037329	BMP4	ENSOCUP00000037329	ENSOCUP00000009545	TGFb_propeptide domain-containing protein.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.612
ENSOCUP00000037329	EGFR	ENSOCUP00000037329	ENSOCUP00000009041	TGFb_propeptide domain-containing protein.	Receptor protein-tyrosine kinase.	0.580
ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000037329	LOC103345451	ENSOCUP00000037329	ENSOCUP00000031740	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.419
ENSOCUP00000044284	BMP4	ENSOCUP00000044284	ENSOCUP00000009545	TGFb_propeptide domain-containing protein.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.612