STRINGSTRING
TNFAIP3 TNFAIP3 PDPK1 PDPK1 NDNF NDNF IL13 IL13 ICAM1 ICAM1 NFE2L2 NFE2L2 IL4 IL4 SCG2 SCG2 RAMP2 RAMP2 GATA3 GATA3 TEK TEK BRAF BRAF FGG FGG ABL1 ABL1 ANGPT1 ANGPT1 FGF21 FGF21 ANGPTL4 ANGPTL4 SERPINE1 SERPINE1 MAPK7 MAPK7 FGA FGA FGB FGB CDH5 CDH5 TNIP2 TNIP2 ABL2 ABL2 KDR KDR KRIT1 KRIT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFAIP3TNF alpha induced protein 3. (787 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa)
NDNFNeuron derived neurotrophic factor. (643 aa)
IL13Interleukin 13. (138 aa)
ICAM1Intercellular adhesion molecule 1. (534 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (677 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa)
SCG2Secretogranin II. (621 aa)
RAMP2Receptor activity modifying protein 2. (100 aa)
GATA3GATA binding protein 3. (444 aa)
TEKTEK receptor tyrosine kinase. (1025 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (767 aa)
FGGFibrinogen gamma chain. (450 aa)
ABL1Tyrosine-protein kinase. (1118 aa)
ANGPT1Angiopoietin 1. (551 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ANGPTL4Angiopoietin like 4. (411 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (362 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (818 aa)
FGAFibrinogen alpha chain. (813 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (492 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (974 aa)
TNIP2TNFAIP3 interacting protein 2. (314 aa)
ABL2Tyrosine-protein kinase. (1146 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
KRIT1Uncharacterized protein. (736 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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