(13 nodes) Regulation of early endosome to late endosome transport network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNX3	PX domain-containing protein. (131 aa)
	RDX	Radixin. (643 aa)
	RAB21	RAB21, member RAS oncogene family. (273 aa)
	ENSOCUP00000034544	FERM domain-containing protein. (508 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
	DAB2	DAB adaptor protein 2. (769 aa)
	SNX12	Sorting nexin 12. (257 aa)
	MAPK3	Mitogen-activated protein kinase. (381 aa)
	MAPK1	Mitogen-activated protein kinase. (364 aa)
	DENND10	DENN domain containing 10. (414 aa)
	PTPN23	Protein tyrosine phosphatase non-receptor type 23. (1630 aa)
	DNAJC13	DnaJ heat shock protein family (Hsp40) member C13. (2236 aa)
	MSN	FERM domain-containing protein. (577 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000034544	RDX	ENSOCUP00000034544	ENSOCUP00000037499	FERM domain-containing protein.	Radixin.	0.715
MAPK1	MAPK3	ENSOCUP00000011783	ENSOCUP00000011800	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.903
MAPK1	PTPN23	ENSOCUP00000011783	ENSOCUP00000002733	Mitogen-activated protein kinase.	Protein tyrosine phosphatase non-receptor type 23.	0.490
MAPK3	MAPK1	ENSOCUP00000011800	ENSOCUP00000011783	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.903
MAPK3	PTPN23	ENSOCUP00000011800	ENSOCUP00000002733	Mitogen-activated protein kinase.	Protein tyrosine phosphatase non-receptor type 23.	0.490
MSN	RDX	ENSOCUP00000000131	ENSOCUP00000037499	FERM domain-containing protein.	Radixin.	0.999
PTPN23	MAPK1	ENSOCUP00000002733	ENSOCUP00000011783	Protein tyrosine phosphatase non-receptor type 23.	Mitogen-activated protein kinase.	0.490
PTPN23	MAPK3	ENSOCUP00000002733	ENSOCUP00000011800	Protein tyrosine phosphatase non-receptor type 23.	Mitogen-activated protein kinase.	0.490
RDX	ENSOCUP00000034544	ENSOCUP00000037499	ENSOCUP00000034544	Radixin.	FERM domain-containing protein.	0.715
RDX	MSN	ENSOCUP00000037499	ENSOCUP00000000131	Radixin.	FERM domain-containing protein.	0.999
SNX12	SNX3	ENSOCUP00000012820	ENSOCUP00000042531	Sorting nexin 12.	PX domain-containing protein.	0.912
SNX3	SNX12	ENSOCUP00000042531	ENSOCUP00000012820	PX domain-containing protein.	Sorting nexin 12.	0.912