(17 nodes) Regulation of skeletal muscle cell differentiation network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	RBFOX1	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. (369 aa)
	DDX17	DEAD-box helicase 17; Belongs to the DEAD box helicase family. (716 aa)
	AKIRIN1	Uncharacterized protein. (191 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator like. (625 aa)
	NLN	Neurolysin, mitochondrial; Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A; Belongs to the peptidase M3 family. (859 aa)
	MSTN	Myostatin. (375 aa)
	TBX1	Uncharacterized protein. (440 aa)
	G1TG26_RABIT	Uncharacterized protein. (191 aa)
	KLHL41	Kelch like family member 41. (606 aa)
	MYOCD	Myocardin. (989 aa)
	RBM24	RNA binding motif protein 24. (192 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (709 aa)
	UQCC2	Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (612 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
	ENSOCUP00000046157	Uncharacterized protein. (147 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKIRIN1	MSTN	ENSOCUP00000004769	ENSOCUP00000010893	Uncharacterized protein.	Myostatin.	0.403
ARNTL	NR1D2	ENSOCUP00000005145	ENSOCUP00000042306	Aryl hydrocarbon receptor nuclear translocator like.	Nuclear receptor subfamily 1 group D member 2.	0.880
DDX17	DDX5	ENSOCUP00000004311	ENSOCUP00000043262	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.924
DDX5	DDX17	ENSOCUP00000043262	ENSOCUP00000004311	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.924
MEF2C	MYOCD	ENSOCUP00000047636	ENSOCUP00000023668	Myocyte enhancer factor 2C.	Myocardin.	0.775
MSTN	AKIRIN1	ENSOCUP00000010893	ENSOCUP00000004769	Myostatin.	Uncharacterized protein.	0.403
MYOCD	MEF2C	ENSOCUP00000023668	ENSOCUP00000047636	Myocardin.	Myocyte enhancer factor 2C.	0.775
NR1D2	ARNTL	ENSOCUP00000042306	ENSOCUP00000005145	Nuclear receptor subfamily 1 group D member 2.	Aryl hydrocarbon receptor nuclear translocator like.	0.880
RBFOX1	RBM24	ENSOCUP00000001045	ENSOCUP00000029468	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events.	RNA binding motif protein 24.	0.793
RBM24	RBFOX1	ENSOCUP00000029468	ENSOCUP00000001045	RNA binding motif protein 24.	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events.	0.793