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MYOM3 MYOM3 NKX2-5 NKX2-5 SMTNL2 SMTNL2 FHOD3 FHOD3 SYNC SYNC DES DES LRRC30 LRRC30 TNNT3 TNNT3 SMPX SMPX MYBPC3 MYBPC3 C7orf57 C7orf57 PDLIM3 PDLIM3 ANKRD1 ANKRD1 ACTC1 ACTC1 ANKRD2 ANKRD2 TNNC1 TNNC1 LMOD3 LMOD3 SYNPO2 SYNPO2 KCTD6 KCTD6 CFL2 CFL2 MYPN MYPN BMP10 BMP10 TNNI1 TNNI1 FHL3 FHL3 TMOD3 TMOD3 MYOM2 MYOM2 MYOZ3 MYOZ3 TRIM63 TRIM63 PDLIM1 PDLIM1 TMOD1 TMOD1 CHORDC1 CHORDC1 MYOT MYOT C10orf71 C10orf71 FBXL22 FBXL22 DMD DMD SRI SRI TRIM54 TRIM54 LRRC10 LRRC10 LRRC2 LRRC2 ANK1 ANK1 UNC45B UNC45B TRIM32 TRIM32 KY KY TNNT2 TNNT2 CAVIN4 CAVIN4 G1TQ93_RABIT G1TQ93_RABIT KLHL41 KLHL41 G1TRH9_RABIT G1TRH9_RABIT ADPRHL1 ADPRHL1 G1TTX7_RABIT G1TTX7_RABIT RTL5 RTL5 SMTNL1 SMTNL1 TCAP TCAP TMOD4 TMOD4 PYROXD1 PYROXD1 NEXN NEXN LRRC39 LRRC39 ACTN3 ACTN3 ASB2 ASB2 SYNPO2L SYNPO2L LMOD1 LMOD1 SPHKAP SPHKAP LOC108176793 LOC108176793 MYL2 MYL2 MYL3 MYL3 MYOZ2 MYOZ2 LMOD2 LMOD2 ENSOCUP00000030887 ENSOCUP00000030887 PRRC2B PRRC2B ATP2A1 ATP2A1 MTM1 MTM1 FLNB FLNB SLC8A1 SLC8A1 PPP1R12B PPP1R12B SLC4A1 SLC4A1 CAPN3 CAPN3 ENSOCUP00000035159 ENSOCUP00000035159 ANK2 ANK2 PAK1 PAK1 CSRP3 CSRP3 ITGB1BP2 ITGB1BP2 PPP2R5A PPP2R5A MYL4 MYL4 TTN TTN ENSOCUP00000039601 ENSOCUP00000039601 LDB3 LDB3 TMOD2 TMOD2 ALDOA ALDOA NEBL NEBL MYOM1 MYOM1 KLHL40 KLHL40 XIRP2 XIRP2 EVA1C EVA1C ILK ILK FLNC FLNC ACTN2 ACTN2 NEB NEB FHL2 FHL2 PPP1R12A PPP1R12A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYOM3Myomesin 3. (1424 aa)
NKX2-5NK2 homeobox 5. (326 aa)
SMTNL2Smoothelin like 2. (568 aa)
FHOD3Formin homology 2 domain containing 3. (1602 aa)
SYNCSyncoilin, intermediate filament protein; Belongs to the intermediate filament family. (475 aa)
DESIF rod domain-containing protein; Belongs to the intermediate filament family. (513 aa)
LRRC30Leucine rich repeat containing 30. (301 aa)
TNNT3Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (202 aa)
SMPXSmall muscle protein X-linked. (88 aa)
MYBPC3Myosin binding protein C, cardiac. (1250 aa)
C7orf57Chromosome 7 open reading frame 57. (283 aa)
PDLIM3PDZ and LIM domain 3. (363 aa)
ANKRD1Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes (By similarity). (319 aa)
ACTC1Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa)
ANKRD2Ankyrin repeat domain 2. (371 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (161 aa)
LMOD3Leiomodin 3. (556 aa)
SYNPO2Synaptopodin 2. (1259 aa)
KCTD6Potassium channel tetramerization domain containing 6. (237 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (195 aa)
MYPNMyopalladin. (1381 aa)
BMP10Bone morphogenetic protein 10. (428 aa)
TNNI1Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (187 aa)
FHL3Four and a half LIM domains 3. (280 aa)
TMOD3Uncharacterized protein. (352 aa)
MYOM2Myomesin 2. (1415 aa)
MYOZ3Myozenin 3. (245 aa)
TRIM63Tripartite motif containing 63. (400 aa)
PDLIM1PDZ and LIM domain 1. (330 aa)
TMOD1Tropomodulin 1. (359 aa)
CHORDC1Uncharacterized protein. (331 aa)
MYOTMyotilin. (806 aa)
C10orf71Chromosome 10 open reading frame 71. (1361 aa)
FBXL22Uncharacterized protein. (229 aa)
DMDUncharacterized protein. (956 aa)
SRIUncharacterized protein. (422 aa)
TRIM54Uncharacterized protein. (364 aa)
LRRC10Uncharacterized protein. (257 aa)
LRRC2Leucine rich repeat containing 2. (371 aa)
ANK1Ankyrin 1. (1421 aa)
UNC45BUnc-45 myosin chaperone B. (929 aa)
TRIM32Tripartite motif containing 32. (659 aa)
KYKyphoscoliosis peptidase. (663 aa)
TNNT2Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (341 aa)
CAVIN4Caveolae associated protein 4. (355 aa)
G1TQ93_RABITUncharacterized protein. (772 aa)
KLHL41Kelch like family member 41. (606 aa)
G1TRH9_RABITUncharacterized protein. (116 aa)
ADPRHL1ADP-ribosylhydrolase like 1. (353 aa)
G1TTX7_RABITUncharacterized protein. (641 aa)
RTL5Retrotransposon Gag like 5. (549 aa)
SMTNL1Smoothelin like 1. (459 aa)
TCAPTitin-cap. (179 aa)
TMOD4Tropomodulin 4 (Predicted). (345 aa)
PYROXD1Pyridine nucleotide-disulphide oxidoreductase domain 1. (502 aa)
NEXNNexilin F-actin binding protein. (696 aa)
LRRC39Leucine rich repeat containing 39. (329 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (900 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (603 aa)
SYNPO2LSynaptopodin 2 like. (744 aa)
LMOD1Leiomodin 1. (915 aa)
SPHKAPSPHK1 interactor, AKAP domain containing. (1730 aa)
LOC108176793Uncharacterized protein. (139 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa)
MYL3Myosin light chain 3. (327 aa)
MYOZ2Myozenin 2. (282 aa)
LMOD2Leiomodin 2. (579 aa)
ENSOCUP00000030887Uncharacterized protein. (2737 aa)
PRRC2BProline rich coiled-coil 2B. (2295 aa)
ATP2A1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. (984 aa)
MTM1Myotubularin 1. (658 aa)
FLNBFilamin-B; Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton (By similarity). (2695 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1056 aa)
SLC4A1Anion exchange protein. (981 aa)
CAPN3Uncharacterized protein; Belongs to the peptidase C2 family. (820 aa)
ENSOCUP00000035159Tnp_22_dsRBD domain-containing protein. (353 aa)
ANK2Ankyrin 2. (3805 aa)
PAK1Non-specific serine/threonine protein kinase. (585 aa)
CSRP3Cysteine and glycine rich protein 3. (245 aa)
ITGB1BP2Integrin subunit beta 1 binding protein 2. (353 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (495 aa)
MYL4Myosin light chain 4. (230 aa)
TTNUncharacterized protein. (569 aa)
ENSOCUP00000039601CHORD domain-containing protein. (119 aa)
LDB3LIM domain binding 3. (768 aa)
TMOD2Tropomodulin 2. (378 aa)
ALDOAFructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. Belongs to the class I fructose-bisphosphate aldolase family. (419 aa)
NEBLNebulette. (1035 aa)
MYOM1Myomesin 1. (1776 aa)
KLHL40Kelch like family member 40. (799 aa)
XIRP2Xin actin binding repeat containing 2. (3529 aa)
EVA1CUncharacterized protein. (535 aa)
ILKIntegrin linked kinase. (510 aa)
FLNCFilamin C. (2628 aa)
ACTN2Actinin alpha 2. (893 aa)
NEBNebulin. (6666 aa)
FHL2Four and a half LIM domains 2. (306 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1085 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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