(7 nodes) Interferon regulatory factor complex network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TLR3	TIR domain-containing protein; Belongs to the Toll-like receptor family. (867 aa)
	G1U1Z9_RABIT	Uncharacterized protein. (242 aa)
	IFNB1	Interferon beta 1. (180 aa)
	IRF7	Interferon regulatory factor 7. (438 aa)
	STAT4	Signal transducer and activator of transcription. (752 aa)
	TBK1	TANK binding kinase 1. (836 aa)
	IRF5	Interferon regulatory factor 5. (500 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1U1Z9_RABIT	IFNB1	ENSOCUP00000023391	ENSOCUP00000020497	Uncharacterized protein.	Interferon beta 1.	0.654
G1U1Z9_RABIT	IRF7	ENSOCUP00000023391	ENSOCUP00000002020	Uncharacterized protein.	Interferon regulatory factor 7.	0.824
G1U1Z9_RABIT	STAT4	ENSOCUP00000023391	ENSOCUP00000031601	Uncharacterized protein.	Signal transducer and activator of transcription.	0.511
G1U1Z9_RABIT	TBK1	ENSOCUP00000023391	ENSOCUP00000035620	Uncharacterized protein.	TANK binding kinase 1.	0.977
G1U1Z9_RABIT	TLR3	ENSOCUP00000023391	ENSOCUP00000015256	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.666
IFNB1	G1U1Z9_RABIT	ENSOCUP00000020497	ENSOCUP00000023391	Interferon beta 1.	Uncharacterized protein.	0.654
IFNB1	IRF5	ENSOCUP00000020497	ENSOCUP00000008702	Interferon beta 1.	Interferon regulatory factor 5.	0.582
IFNB1	IRF7	ENSOCUP00000020497	ENSOCUP00000002020	Interferon beta 1.	Interferon regulatory factor 7.	0.978
IFNB1	STAT4	ENSOCUP00000020497	ENSOCUP00000031601	Interferon beta 1.	Signal transducer and activator of transcription.	0.524
IFNB1	TBK1	ENSOCUP00000020497	ENSOCUP00000035620	Interferon beta 1.	TANK binding kinase 1.	0.911
IFNB1	TLR3	ENSOCUP00000020497	ENSOCUP00000015256	Interferon beta 1.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.957
IRF5	IFNB1	ENSOCUP00000008702	ENSOCUP00000020497	Interferon regulatory factor 5.	Interferon beta 1.	0.582
IRF5	STAT4	ENSOCUP00000008702	ENSOCUP00000031601	Interferon regulatory factor 5.	Signal transducer and activator of transcription.	0.465
IRF5	TBK1	ENSOCUP00000008702	ENSOCUP00000035620	Interferon regulatory factor 5.	TANK binding kinase 1.	0.702
IRF5	TLR3	ENSOCUP00000008702	ENSOCUP00000015256	Interferon regulatory factor 5.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.717
IRF7	G1U1Z9_RABIT	ENSOCUP00000002020	ENSOCUP00000023391	Interferon regulatory factor 7.	Uncharacterized protein.	0.824
IRF7	IFNB1	ENSOCUP00000002020	ENSOCUP00000020497	Interferon regulatory factor 7.	Interferon beta 1.	0.978
IRF7	STAT4	ENSOCUP00000002020	ENSOCUP00000031601	Interferon regulatory factor 7.	Signal transducer and activator of transcription.	0.593
IRF7	TBK1	ENSOCUP00000002020	ENSOCUP00000035620	Interferon regulatory factor 7.	TANK binding kinase 1.	0.994
IRF7	TLR3	ENSOCUP00000002020	ENSOCUP00000015256	Interferon regulatory factor 7.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.920