STRINGSTRING
CACNG2 CACNG2 ENSOCUP00000048545 ENSOCUP00000048545 NPNT NPNT GABBR1 GABBR1 IFNAR1 IFNAR1 DLG4 DLG4 ITGA8 ITGA8 ENSOCUP00000045780 ENSOCUP00000045780 ITGB8 ITGB8 VWC2L VWC2L ITGAE ITGAE INSR INSR ENSOCUP00000042001 ENSOCUP00000042001 TF TF AMHR2 AMHR2 GRIA4 GRIA4 CCL25 CCL25 CD3D CD3D LRRTM4 LRRTM4 ITGB2 ITGB2 ITGAV ITGAV BMPR2 BMPR2 GRIN2A GRIN2A ERBB4 ERBB4 IL6R IL6R CHRNA6 CHRNA6 TGFBR1 TGFBR1 CHRNA4 CHRNA4 SLC2A4 SLC2A4 OLFM3 OLFM3 MYD88 MYD88 CD40 CD40 HTR3B HTR3B ENSOCUP00000033540 ENSOCUP00000033540 CD79B CD79B IL20RB IL20RB GRIK5 GRIK5 ITGAD ITGAD CHRNG CHRNG ITGB4 ITGB4 CD4 CD4 TGFBR2 TGFBR2 CACNG5 CACNG5 CSF2RA CSF2RA IRAK1 IRAK1 ITGA2 ITGA2 ITGB6 ITGB6 LOC100341420 LOC100341420 MADCAM1 MADCAM1 ITGA7 ITGA7 CR2 CR2 ITGAM ITGAM NIPAL3 NIPAL3 ITGA9 ITGA9 ICAM1 ICAM1 U3KPA1_RABIT U3KPA1_RABIT IFNLR1 IFNLR1 SPN SPN IL23R IL23R G1U7R8_RABIT G1U7R8_RABIT CHRND CHRND AADACL3 AADACL3 GRIN3A GRIN3A G1U0P1_RABIT G1U0P1_RABIT G1TZQ7_RABIT G1TZQ7_RABIT AICDA AICDA RAMP2 RAMP2 ITGA4 ITGA4 G1TXX5_RABIT G1TXX5_RABIT GRIN2C GRIN2C TVA1_RABIT TVA1_RABIT CHRNA9 CHRNA9 IL-15L IL-15L HTR3A HTR3A MCMDC2 MCMDC2 G1TUA1_RABIT G1TUA1_RABIT CHRNA5 CHRNA5 CD3E CD3E G1TP12_RABIT G1TP12_RABIT G1TMC4_RABIT G1TMC4_RABIT CSF2RB CSF2RB IL6 IL6 GP9 GP9 TLR1 TLR1 GRIA2 GRIA2 ACVRL1 ACVRL1 ACVR1B ACVR1B ITGA11 ITGA11 SYK SYK ITGAX ITGAX NIPAL2 NIPAL2 NETO2 NETO2 ERBB3 ERBB3 DLG3 DLG3 TFRC TFRC BMPR1A BMPR1A G1TCA5_RABIT G1TCA5_RABIT GABBR2 GABBR2 IL18R1 IL18R1 ACVR2A ACVR2A SDCBP SDCBP IL20RA IL20RA IL5RA IL5RA GRIN2B GRIN2B IGF1R IGF1R IL13RA2 IL13RA2 ITGB5 ITGB5 IL27RA IL27RA ITGAL ITGAL CACNG4 CACNG4 CALCRL CALCRL IL13RA1 IL13RA1 G1T5T5_RABIT G1T5T5_RABIT FAM189A2 FAM189A2 ITGA5 ITGA5 GRM5 GRM5 OSMR OSMR FAM189A1 FAM189A1 AASDH AASDH G1T1V3_RABIT G1T1V3_RABIT GRID2 GRID2 ITGA1 ITGA1 BMP4 BMP4 SCP2D1 SCP2D1 INSRR INSRR ERBB2 ERBB2 FOXP3 FOXP3 FN1 FN1 LOC100350832 LOC100350832 ITGA3 ITGA3 HTR2A HTR2A ACVR1C ACVR1C TRAF5 TRAF5 CCR9 CCR9 IL6ST IL6ST CNIH3 CNIH3 CHRNA2 CHRNA2 CHRNB1 CHRNB1 LOC100344381 LOC100344381 IL1R1 IL1R1 GRM1 GRM1 EMILIN1 EMILIN1 GPR156 GPR156 IL9 IL9 HJV HJV IL18RAP IL18RAP TLR6 TLR6 ZAP70 ZAP70 GRIK3 GRIK3 CHRNB3 CHRNB3 CHRNA3 CHRNA3 OLFM2 OLFM2 IL5 IL5 CACNG3 CACNG3 PTCRA PTCRA GRIK2 GRIK2 TLR10 TLR10 TRAF3 TRAF3 ITGB1 ITGB1 CSF2 CSF2 AADACL4 AADACL4 TLR2 TLR2 ITGA2B ITGA2B LYN LYN ITGA10 ITGA10 TRAT1 TRAT1 GRIK4 GRIK4 CHRNA7 CHRNA7 ACVR1 ACVR1 ITGB7 ITGB7 GP1BA GP1BA ABHD6 ABHD6 CD3G CD3G ITGA6 ITGA6 IL4R IL4R GRIA3 GRIA3 IL13 IL13
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (256 aa)
ENSOCUP00000048545Uncharacterized protein. (222 aa)
NPNTNephronectin. (837 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1043 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (541 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1100 aa)
ENSOCUP00000045780Ig-like domain-containing protein. (172 aa)
ITGB8Integrin beta-8; Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta- 1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (By similarity). Required during vasculogenesis (By similarity). (772 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (251 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1182 aa)
INSRTyrosine-protein kinase receptor. (1377 aa)
ENSOCUP00000042001Ig-like domain-containing protein. (185 aa)
TFSerotransferrin; Belongs to the transferrin family. (717 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (569 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
CCL25SCY domain-containing protein. (159 aa)
CD3DIg_4 domain-containing protein. (177 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (591 aa)
ITGB2Integrin beta. (1009 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1087 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
IL6RInterleukin 6 receptor. (569 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (542 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (486 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (620 aa)
SLC2A4MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (574 aa)
OLFM3Olfactomedin 3. (478 aa)
MYD88Uncharacterized protein. (476 aa)
CD40Uncharacterized protein. (494 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
ENSOCUP00000033540Ig-like domain-containing protein. (203 aa)
CD79BCD79b molecule. (282 aa)
IL20RBInterleukin 20 receptor subunit beta. (307 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (922 aa)
ITGADIntegrin subunit alpha D; Belongs to the integrin alpha chain family. (1237 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (497 aa)
ITGB4Integrin beta. (1708 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
CSF2RAFibronectin type-III domain-containing protein. (443 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (534 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (787 aa)
LOC100341420Uncharacterized protein. (183 aa)
MADCAM1Uncharacterized protein. (344 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
CR2Complement C3d receptor 2. (1084 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1258 aa)
NIPAL3NIPA like domain containing 3. (440 aa)
ITGA9Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (597 aa)
ICAM1Intercellular adhesion molecule 1. (534 aa)
U3KPA1_RABITANF_receptor domain-containing protein. (237 aa)
IFNLR1Interferon lambda receptor 1. (639 aa)
SPNUncharacterized protein. (555 aa)
IL23RInterleukin 23 receptor. (622 aa)
G1U7R8_RABITUncharacterized protein. (311 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (695 aa)
AADACL3Arylacetamide deacetylase like 3. (407 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
G1U0P1_RABITUncharacterized protein. (209 aa)
G1TZQ7_RABITUncharacterized protein. (365 aa)
AICDAActivation induced cytidine deaminase. (198 aa)
RAMP2Receptor activity modifying protein 2. (100 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa)
G1TXX5_RABITIg-like domain-containing protein. (136 aa)
GRIN2CUncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (671 aa)
TVA1_RABITT-cell receptor alpha chain V region RL-5. (239 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
IL-15LInterleukin 15-like protein. (136 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (513 aa)
MCMDC2Minichromosome maintenance domain containing 2. (680 aa)
G1TUA1_RABITIg-like domain-containing protein. (169 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (474 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (201 aa)
G1TP12_RABITUncharacterized protein. (166 aa)
G1TMC4_RABITIg-like domain-containing protein. (181 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (868 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
GP9Glycoprotein IX platelet. (164 aa)
TLR1TIR domain-containing protein; Belongs to the Toll-like receptor family. (796 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (327 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (474 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1151 aa)
SYKTyrosine-protein kinase. (630 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1060 aa)
NIPAL2Uncharacterized protein. (211 aa)
NETO2Neuropilin and tolloid like 2. (525 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1339 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa)
TFRCTransferrin receptor. (763 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
G1TCA5_RABITUncharacterized protein. (186 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (880 aa)
IL18R1Uncharacterized protein. (540 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (556 aa)
SDCBPSyndecan binding protein. (312 aa)
IL20RAInterleukin 20 receptor subunit alpha. (548 aa)
IL5RAIL6Ra-bind domain-containing protein. (332 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
IGF1RTyrosine-protein kinase receptor. (1464 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (361 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
IL27RAInterleukin 27 receptor subunit alpha. (634 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1241 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (341 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (465 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (519 aa)
G1T5T5_RABITUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (188 aa)
FAM189A2Family with sequence similarity 189 member A2. (450 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa)
GRM5Glutamate metabotropic receptor 5. (988 aa)
OSMROncostatin M receptor. (1088 aa)
FAM189A1Family with sequence similarity 189 member A1. (564 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1092 aa)
G1T1V3_RABITNeur_chan_memb domain-containing protein. (223 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1178 aa)
BMP4Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
SCP2D1SCP2 sterol binding domain containing 1. (156 aa)
INSRRTyrosine-protein kinase receptor. (1320 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
FOXP3Forkhead box P3. (455 aa)
FN1Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2427 aa)
LOC100350832Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (437 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1072 aa)
HTR2A5-hydroxytryptamine receptor 2A. (469 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (507 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (504 aa)
LOC100344381Uncharacterized protein. (450 aa)
IL1R1Interleukin 1 receptor type 1. (699 aa)
GRM1Glutamate metabotropic receptor 1. (1203 aa)
EMILIN1Elastin microfibril interfacer 1. (982 aa)
GPR156G protein-coupled receptor 156. (801 aa)
IL9Interleukin 9. (143 aa)
HJVHemojuvelin BMP co-receptor. (427 aa)
IL18RAPInterleukin 18 receptor accessory protein. (599 aa)
TLR6TIR domain-containing protein; Belongs to the Toll-like receptor family. (795 aa)
ZAP70Tyrosine-protein kinase. (623 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (880 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (475 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (500 aa)
OLFM2Olfactomedin 2. (467 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (314 aa)
PTCRAUncharacterized protein. (196 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
TLR10TIR domain-containing protein; Belongs to the Toll-like receptor family. (810 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (830 aa)
CSF2Uncharacterized protein. (144 aa)
AADACL4Uncharacterized protein. (406 aa)
TLR2TIR domain-containing protein; Belongs to the Toll-like receptor family. (784 aa)
ITGA2BIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1008 aa)
LYNTyrosine-protein kinase. (636 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1169 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (185 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
CHRNA7Uncharacterized protein. (513 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (615 aa)
ABHD6Abhydrolase domain containing 6. (399 aa)
CD3GIGc2 domain-containing protein. (182 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (955 aa)
IL4RFibronectin type-III domain-containing protein. (862 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
IL13Interleukin 13. (138 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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