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ATP13A2 ATP13A2 ATP2B3 ATP2B3 NT5C2 NT5C2 ATP2B1 ATP2B1 ATP12A ATP12A LOC100356734 LOC100356734 ATP1A3 ATP1A3 CTDP1 CTDP1 ATP11C ATP11C HDHD2 HDHD2 ATP7B ATP7B ATP11A ATP11A PITPNM3 PITPNM3 ATP9A ATP9A ATP2C1 ATP2C1 LOC100345551 LOC100345551 ENSOCUP00000039044 ENSOCUP00000039044 ATP2A2 ATP2A2 ENOPH1 ENOPH1 ATP2B2 ATP2B2 PMM1 PMM1 ATP11B ATP11B ATP2A3 ATP2A3 ATP9B ATP9B NT5C3A NT5C3A PDXP PDXP ATP13A3 ATP13A3 PUDP PUDP ATP2A1 ATP2A1 ENSOCUP00000029750 ENSOCUP00000029750 ATP10B ATP10B P3H4 P3H4 PSPH PSPH ATP1A2 ATP1A2 ATP1A1 ATP1A1 ATP4A ATP4A CTDNEP1 CTDNEP1 NT5C NT5C LOC100352125 LOC100352125 NT5DC2 NT5DC2 MDP1 MDP1 ATP8A1 ATP8A1 ATP1A4 ATP1A4 ATP8B4 ATP8B4 ATP2B4 ATP2B4 ATP10A ATP10A HDHD3 HDHD3 CTDSPL2 CTDSPL2 PMM2 PMM2 PHOSPHO1 PHOSPHO1 G1TBF4_RABIT G1TBF4_RABIT NT5DC3 NT5DC3 ATP8A2 ATP8A2 ATP7A ATP7A CMAS CMAS CTDSP2 CTDSP2 LPIN3 LPIN3 ACAD10 ACAD10 ATP8B1 ATP8B1 LPIN2 LPIN2 LHPP LHPP HDHD5 HDHD5 ATP10D ATP10D NT5DC4 NT5DC4 LPIN1 LPIN1 NANP NANP UBLCP1 UBLCP1 TIMM50 TIMM50 NT5DC1 NT5DC1 PITPNM2 PITPNM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (738 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1245 aa)
NT5C2Uncharacterized protein. (587 aa)
ATP2B1Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa)
ATP12APotassium-transporting ATPase alpha chain 2; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. (1080 aa)
LOC100356734Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1283 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (964 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
ATP11CPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1132 aa)
HDHD2Haloacid dehalogenase like hydrolase domain containing 2. (297 aa)
ATP7BATPase copper transporting beta. (1465 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1065 aa)
PITPNM3PITPNM family member 3. (1010 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (703 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (949 aa)
LOC100345551Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1170 aa)
ENSOCUP00000039044FCP1 homology domain-containing protein. (142 aa)
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytos [...] (1017 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (363 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1111 aa)
PMM1Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (478 aa)
ATP11BProbable phospholipid-transporting ATPase IF; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (By similarity). Isoform 2/RFBP appears to play a role in the subnuclear trafficking of transcription factors with RING motifs; Belongs to the cation transport [...] (1216 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1074 aa)
ATP9BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1140 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (361 aa)
PDXPUncharacterized protein. (79 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1230 aa)
PUDPPseudouridine 5'-phosphatase. (220 aa)
ATP2A1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. (984 aa)
ENSOCUP00000029750Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (907 aa)
ATP10BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1432 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (539 aa)
PSPHPhosphoserine phosphatase. (225 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1019 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (By similarity). May contribute to blood-heart barrier properties of endocardial endothelium and may control cardiac performance via endothelial Na(+)/H(+) exchange. (956 aa)
ATP4APotassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. (1030 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (256 aa)
NT5C5', 3'-nucleotidase, cytosolic. (237 aa)
LOC100352125FCP1 homology domain-containing protein. (249 aa)
NT5DC25'-nucleotidase domain containing 2. (489 aa)
MDP1Uncharacterized protein. (164 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ATP8B4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1169 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
ATP10APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1506 aa)
HDHD3Haloacid dehalogenase like hydrolase domain containing 3. (251 aa)
CTDSPL2CTD small phosphatase like 2. (450 aa)
PMM2Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (245 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
G1TBF4_RABITPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (523 aa)
NT5DC35'-nucleotidase domain containing 3. (527 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1148 aa)
ATP7AATPase copper transporting alpha. (1499 aa)
CMASCytidine monophosphate N-acetylneuraminic acid synthetase. (495 aa)
CTDSP2FCP1 homology domain-containing protein. (271 aa)
LPIN3Lipin 3. (871 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1061 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
LPIN2Lipin 2. (935 aa)
LHPPPhospholysine phosphohistidine inorganic pyrophosphate phosphatase. (270 aa)
HDHD5Haloacid dehalogenase like hydrolase domain containing 5. (422 aa)
ATP10DPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1396 aa)
NT5DC45'-nucleotidase domain containing 4. (426 aa)
LPIN1Lipin 1. (1106 aa)
NANPN-acetylneuraminic acid phosphatase. (248 aa)
UBLCP1Ubiquitin like domain containing CTD phosphatase 1. (318 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (356 aa)
NT5DC15'-nucleotidase domain containing 1. (538 aa)
PITPNM2Phosphatidylinositol transfer protein membrane associated 2. (1390 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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