(14 nodes) MPN domain network (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABRAXAS2	Abraxas 2, BRISC complex subunit. (440 aa)
	PSMD7	Proteasome 26S subunit, non-ATPase 7. (379 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa)
	STAMBPL1	STAM binding protein like 1. (469 aa)
	NPLOC4	NPL4 homolog, ubiquitin recognition factor. (576 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (317 aa)
	MYSM1	Myb like, SWIRM and MPN domains 1. (831 aa)
	BRCC3	BRCA1/BRCA2-containing complex subunit 3. (291 aa)
	ABRAXAS1	Abraxas 1, BRCA1 A complex subunit. (409 aa)
	COPS5	COP9 signalosome subunit 5. (334 aa)
	PRPF8	Pre-mRNA processing factor 8. (2335 aa)
	COPS6	COP9 signalosome subunit 6. (324 aa)
	STAMBP	STAM binding protein. (432 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (364 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABRAXAS1	BRCC3	ENSOCUP00000011470	ENSOCUP00000021158	Abraxas 1, BRCA1 A complex subunit.	BRCA1/BRCA2-containing complex subunit 3.	0.973
ABRAXAS2	BRCC3	ENSOCUP00000004137	ENSOCUP00000021158	Abraxas 2, BRISC complex subunit.	BRCA1/BRCA2-containing complex subunit 3.	0.995
BRCC3	ABRAXAS1	ENSOCUP00000021158	ENSOCUP00000011470	BRCA1/BRCA2-containing complex subunit 3.	Abraxas 1, BRCA1 A complex subunit.	0.973
BRCC3	ABRAXAS2	ENSOCUP00000021158	ENSOCUP00000004137	BRCA1/BRCA2-containing complex subunit 3.	Abraxas 2, BRISC complex subunit.	0.995
BRCC3	EIF3H	ENSOCUP00000021158	ENSOCUP00000039136	BRCA1/BRCA2-containing complex subunit 3.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.662
BRCC3	NPLOC4	ENSOCUP00000021158	ENSOCUP00000029159	BRCA1/BRCA2-containing complex subunit 3.	NPL4 homolog, ubiquitin recognition factor.	0.488
BRCC3	PSMD7	ENSOCUP00000021158	ENSOCUP00000007557	BRCA1/BRCA2-containing complex subunit 3.	Proteasome 26S subunit, non-ATPase 7.	0.963
COPS5	COPS6	ENSOCUP00000009878	ENSOCUP00000000260	COP9 signalosome subunit 5.	COP9 signalosome subunit 6.	0.999
COPS5	EIF3F	ENSOCUP00000009878	ENSOCUP00000003655	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.737
COPS5	EIF3H	ENSOCUP00000009878	ENSOCUP00000039136	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.749
COPS5	MYSM1	ENSOCUP00000009878	ENSOCUP00000026655	COP9 signalosome subunit 5.	Myb like, SWIRM and MPN domains 1.	0.510
COPS5	NPLOC4	ENSOCUP00000009878	ENSOCUP00000029159	COP9 signalosome subunit 5.	NPL4 homolog, ubiquitin recognition factor.	0.437
COPS5	PRPF8	ENSOCUP00000009878	ENSOCUP00000000075	COP9 signalosome subunit 5.	Pre-mRNA processing factor 8.	0.430
COPS5	PSMD14	ENSOCUP00000009878	ENSOCUP00000047048	COP9 signalosome subunit 5.	Proteasome 26S subunit, non-ATPase 14.	0.672
COPS5	PSMD7	ENSOCUP00000009878	ENSOCUP00000007557	COP9 signalosome subunit 5.	Proteasome 26S subunit, non-ATPase 7.	0.899
COPS5	STAMBP	ENSOCUP00000009878	ENSOCUP00000003171	COP9 signalosome subunit 5.	STAM binding protein.	0.538
COPS5	STAMBPL1	ENSOCUP00000009878	ENSOCUP00000034455	COP9 signalosome subunit 5.	STAM binding protein like 1.	0.583
COPS6	COPS5	ENSOCUP00000000260	ENSOCUP00000009878	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.999
COPS6	EIF3F	ENSOCUP00000000260	ENSOCUP00000003655	COP9 signalosome subunit 6.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.526
COPS6	EIF3H	ENSOCUP00000000260	ENSOCUP00000039136	COP9 signalosome subunit 6.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.759