STRINGSTRING
MFAP3L MFAP3L TGFB3 TGFB3 FBLN1 FBLN1 BMP4 BMP4 GDF5 GDF5 BMP10 BMP10 FN1 FN1 LTBP1 LTBP1 G1SV95_RABIT G1SV95_RABIT FBN2 FBN2 GDF6 GDF6 EMILIN1 EMILIN1 G1SPR7_RABIT G1SPR7_RABIT TGFB2 TGFB2 FBN1 FBN1 ITGB1 ITGB1 BMP6 BMP6 EMILIN2 EMILIN2 ENSOCUP00000040886 ENSOCUP00000040886 ENSOCUP00000041840 ENSOCUP00000041840 LOXL3 LOXL3 ITGB8 ITGB8 LOX LOX ENSOCUP00000044284 ENSOCUP00000044284 ENSOCUP00000045925 ENSOCUP00000045925 ITGA8 ITGA8 BMP7 BMP7 BMP5 BMP5 MFAP3 MFAP3 VTN VTN FBLN5 FBLN5 ITGB6 ITGB6 FURIN FURIN LOC103345451 LOC103345451 ENSOCUP00000032400 ENSOCUP00000032400 ITGB3 ITGB3 LOXL4 LOXL4 ENSOCUP00000037329 ENSOCUP00000037329 FBLN2 FBLN2 ITGAV ITGAV MFAP4 MFAP4 EFEMP1 EFEMP1 ITGB5 ITGB5 LOXL2 LOXL2 LTBP2 LTBP2 ITGA5 ITGA5 EMILIN3 EMILIN3 MFAP5 MFAP5 LOXL1 LOXL1 HHIPL2 HHIPL2 GDF7 GDF7 BMP2 BMP2 FBN3 FBN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MFAP3LMicrofibril associated protein 3 like. (625 aa)
TGFB3Transforming growth factor beta 3. (458 aa)
FBLN1Fibulin 1. (457 aa)
BMP4Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
GDF5Growth differentiation factor 5 preproprotein (Predicted). (500 aa)
BMP10Bone morphogenetic protein 10. (428 aa)
FN1Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2427 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1705 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
FBN2Fibrillin 2. (2912 aa)
GDF6Growth differentiation factor 6. (427 aa)
EMILIN1Elastin microfibril interfacer 1. (982 aa)
G1SPR7_RABITUncharacterized protein. (297 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FBN1Fibrillin 1. (2831 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (830 aa)
BMP6Bone morphogenetic protein 6. (411 aa)
EMILIN2Elastin microfibril interfacer 2. (1133 aa)
ENSOCUP00000040886Uncharacterized protein. (420 aa)
ENSOCUP00000041840TGFb_propeptide domain-containing protein. (219 aa)
LOXL3Lysyl oxidase like 3. (935 aa)
ITGB8Integrin beta-8; Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta- 1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (By similarity). Required during vasculogenesis (By similarity). (772 aa)
LOXLysyl oxidase. (419 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ENSOCUP00000045925TGFb_propeptide domain-containing protein. (272 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1100 aa)
BMP7TGF_BETA_2 domain-containing protein. (170 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
MFAP3Microfibril associated protein 3. (362 aa)
VTNVitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. (475 aa)
FBLN5Fibulin 5. (453 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (787 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (666 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
ENSOCUP00000032400Uncharacterized protein. (531 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (873 aa)
LOXL4Lysyl oxidase like 4. (803 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
FBLN2Fibulin 2. (1286 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
MFAP4Microfibril associated protein 4. (258 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (494 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
LOXL2Lysyl oxidase like 2. (987 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1809 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa)
EMILIN3Elastin microfibril interfacer 3. (766 aa)
MFAP5Microfibril associated protein 5. (171 aa)
LOXL1Lysyl oxidase like 1. (535 aa)
HHIPL2HHIP like 2. (720 aa)
GDF7Growth differentiation factor 7. (546 aa)
BMP2Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. (271 aa)
FBN3Fibrillin 3. (2647 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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