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TMOD2 TMOD2 DES DES TNNT3 TNNT3 MYBPC3 MYBPC3 MYH7B MYH7B MYH4 MYH4 LOC100008687 LOC100008687 LOC100349893 LOC100349893 TNNC1 TNNC1 VIM VIM TPM4 TPM4 MYH8 MYH8 TNNI1 TNNI1 TMOD3 TMOD3 TMOD1 TMOD1 TPM1 TPM1 DMD DMD MYBPC1 MYBPC1 MYH1 MYH1 TNNT2 TNNT2 G1TQ93_RABIT G1TQ93_RABIT G1TRH9_RABIT G1TRH9_RABIT G1TTX7_RABIT G1TTX7_RABIT MYH7 MYH7 TCAP TCAP TMOD4 TMOD4 MYH13 MYH13 ACTN3 ACTN3 MYL2 MYL2 MYL3 MYL3 ENSOCUP00000030887 ENSOCUP00000030887 ENSOCUP00000031603 ENSOCUP00000031603 MYL4 MYL4 MYL1 MYL1 TTN TTN ENSOCUP00000039758 ENSOCUP00000039758 TPM2 TPM2 NEB NEB ACTN2 ACTN2 ENSOCUP00000044587 ENSOCUP00000044587 ENSOCUP00000042786 ENSOCUP00000042786 ENSOCUP00000042061 ENSOCUP00000042061
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMOD2Tropomodulin 2. (378 aa)
DESIF rod domain-containing protein; Belongs to the intermediate filament family. (513 aa)
TNNT3Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (202 aa)
MYBPC3Myosin binding protein C, cardiac. (1250 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa)
MYH4Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
LOC100008687Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
LOC100349893Uncharacterized protein; Belongs to the tropomyosin family. (205 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (161 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
TPM4Tropomyosin 4; Belongs to the tropomyosin family. (410 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
TNNI1Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (187 aa)
TMOD3Uncharacterized protein. (352 aa)
TMOD1Tropomodulin 1. (359 aa)
TPM1Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (326 aa)
DMDUncharacterized protein. (956 aa)
MYBPC1Myosin binding protein C, slow type. (1173 aa)
MYH1Myosin-4; Muscle contraction. (1938 aa)
TNNT2Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (341 aa)
G1TQ93_RABITUncharacterized protein. (772 aa)
G1TRH9_RABITUncharacterized protein. (116 aa)
G1TTX7_RABITUncharacterized protein. (641 aa)
MYH7Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
TCAPTitin-cap. (179 aa)
TMOD4Tropomodulin 4 (Predicted). (345 aa)
MYH13Skeletal muscle myosin heavy chain MyHC-EO/IIL; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (900 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa)
MYL3Myosin light chain 3. (327 aa)
ENSOCUP00000030887Uncharacterized protein. (2737 aa)
ENSOCUP00000031603Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1110 aa)
MYL4Myosin light chain 4. (230 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. (193 aa)
TTNUncharacterized protein. (569 aa)
ENSOCUP00000039758Myosin_tail_1 domain-containing protein. (230 aa)
TPM2Tropomyosin beta chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. (352 aa)
NEBNebulin. (6666 aa)
ACTN2Actinin alpha 2. (893 aa)
ENSOCUP00000044587Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (295 aa)
ENSOCUP00000042786Uncharacterized protein. (108 aa)
ENSOCUP00000042061Uncharacterized protein. (83 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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