STRINGSTRING
SIGMAR1 SIGMAR1 WIPF3 WIPF3 KPNA4 KPNA4 VPS33A VPS33A LOC100353390 LOC100353390 IPO4 IPO4 CHMP4A CHMP4A SV2B SV2B LOC100353390-2 LOC100353390-2 G3BP2 G3BP2 SV2A SV2A IPO5 IPO5 IL17A IL17A IL17F IL17F VPS18 VPS18 IL18 IL18 WIPF2 WIPF2 SRPK2 SRPK2 ZDHHC5 ZDHHC5 KPNA5 KPNA5 CBX1 CBX1 WASL WASL P2RX7 P2RX7 PSIP1 PSIP1 NLRP12 NLRP12 LOC103351333 LOC103351333 GRSF1 GRSF1 RCAN1 RCAN1 RPN1 RPN1 H2AC1 H2AC1 TIMD4 TIMD4 VPS16 VPS16 NUP205 NUP205 G1T4I8_RABIT G1T4I8_RABIT LARP1B LARP1B SNRPB SNRPB DAD1 DAD1 LOC100348835 LOC100348835 STT3A STT3A MOGS MOGS WAS WAS GEMIN6 GEMIN6 G1T9X6_RABIT G1T9X6_RABIT PATJ PATJ SIKE1 SIKE1 EDEM2 EDEM2 GANAB GANAB STX1A STX1A G1TEW3_RABIT G1TEW3_RABIT CORO1A CORO1A G1TGF3_RABIT G1TGF3_RABIT VPS11 VPS11 RANBP1 RANBP1 STT3B STT3B PACS2 PACS2 LOC100355669 LOC100355669 MDP1 MDP1 IL6 IL6 LOC100354654 LOC100354654 APOBEC3A APOBEC3A LOC100357194 LOC100357194 TMPRSS2 TMPRSS2 HSPG2 HSPG2 G1TNN9_RABIT G1TNN9_RABIT G1TPR7_RABIT G1TPR7_RABIT IL10 IL10 RCAN2 RCAN2 CORO1C CORO1C G1TT13_RABIT G1TT13_RABIT VAMP1 VAMP1 G1TUI3_RABIT G1TUI3_RABIT CORO6 CORO6 GPS2 GPS2 ZDHHC20 ZDHHC20 IL17RA IL17RA GSK3A GSK3A G1U118_RABIT G1U118_RABIT ENSOCUP00000023088 ENSOCUP00000023088 VPS39 VPS39 SV2C SV2C G1U611_RABIT G1U611_RABIT G1U7T7_RABIT G1U7T7_RABIT RANBP6 RANBP6 CHMP1A CHMP1A G1U996_RABIT G1U996_RABIT RHBDF1 RHBDF1 U3KMN0_RABIT U3KMN0_RABIT TGFBRAP1 TGFBRAP1 ACP1 ACP1 CNBP CNBP ENSOCUP00000031112 ENSOCUP00000031112 RPN2 RPN2 NMI NMI ENSOCUP00000031561 ENSOCUP00000031561 ZDHHC1 ZDHHC1 CRBN CRBN KPNA7 KPNA7 MPDZ MPDZ ENSOCUP00000035366 ENSOCUP00000035366 SRPK1 SRPK1 TUFM TUFM PDZD3 PDZD3 ENSOCUP00000036385 ENSOCUP00000036385 KPNA3 KPNA3 ZDHHC3 ZDHHC3 HAVCR2 HAVCR2 ENSOCUP00000037105 ENSOCUP00000037105 RHBDF2 RHBDF2 ENSOCUP00000038330 ENSOCUP00000038330 ENSOCUP00000038512 ENSOCUP00000038512 LARP1 LARP1 VPS33B VPS33B VPS41 VPS41 CORO2B CORO2B CORO2A CORO2A CHMP1B CHMP1B ELK1 ELK1 LOC100356234 LOC100356234 ENSOCUP00000044275 ENSOCUP00000044275 PACS1 PACS1 ANTXR1 ANTXR1 ENSOCUP00000045000 ENSOCUP00000045000 ANTXR2 ANTXR2 ENSOCUP00000045820 ENSOCUP00000045820 RNF135 RNF135 IL17RC IL17RC MPP5 MPP5 TRIM4 TRIM4 LOC100353286 LOC100353286
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
WIPF3WAS/WASL interacting protein family member 3. (447 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (523 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (595 aa)
LOC100353390Uncharacterized protein. (189 aa)
IPO4Importin 4. (1079 aa)
CHMP4ACharged multivesicular body protein 4A. (279 aa)
SV2BSynaptic vesicle glycoprotein 2B. (664 aa)
LOC100353390-2Uncharacterized protein. (190 aa)
G3BP2G3BP stress granule assembly factor 2. (482 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
IPO5Importin 5. (1082 aa)
IL17AInterleukin 17A. (153 aa)
IL17FInterleukin 17F. (163 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
IL18Uncharacterized protein. (408 aa)
WIPF2WH2 domain-containing protein. (439 aa)
SRPK2SRSF protein kinase 2. (739 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (577 aa)
CBX1Uncharacterized protein. (185 aa)
WASLWASP like actin nucleation promoting factor. (512 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
PSIP1PC4 and SFRS1 interacting protein 1. (531 aa)
NLRP12NLR family pyrin domain containing 12. (1060 aa)
LOC103351333VWFA domain-containing protein. (564 aa)
GRSF1G-rich RNA sequence binding factor 1. (420 aa)
RCAN1Regulator of calcineurin 1. (197 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (607 aa)
H2AC1Histone H2A; Belongs to the histone H2A family. (131 aa)
TIMD4T cell immunoglobulin and mucin domain containing 4. (368 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
NUP205Nucleoporin 205. (2010 aa)
G1T4I8_RABITUncharacterized protein. (1307 aa)
LARP1BLa ribonucleoprotein domain family member 1B. (919 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
DAD1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
LOC100348835Histone H2B; Belongs to the histone H2B family. (126 aa)
STT3ASTT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
MOGSGlyco_hydro_63N domain-containing protein. (291 aa)
WASWASP actin nucleation promoting factor. (527 aa)
GEMIN6Gem nuclear organelle associated protein 6. (167 aa)
G1T9X6_RABITUncharacterized protein. (188 aa)
PATJPATJ crumbs cell polarity complex component. (1798 aa)
SIKE1Suppressor of IKBKE 1. (222 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (575 aa)
GANABGlucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (966 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (315 aa)
G1TEW3_RABITUncharacterized protein. (478 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (441 aa)
G1TGF3_RABITSmall nuclear ribonucleoprotein-associated protein. (240 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
RANBP1RAN binding protein 1. (266 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (788 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (537 aa)
LOC100355669Uncharacterized protein. (190 aa)
MDP1Uncharacterized protein. (164 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
LOC100354654Uncharacterized protein. (189 aa)
APOBEC3ACMP/dCMP-type deaminase domain-containing protein. (250 aa)
LOC100357194Uncharacterized protein. (189 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (612 aa)
HSPG2Heparan sulfate proteoglycan 2. (4207 aa)
G1TNN9_RABITAnth_Ig domain-containing protein. (239 aa)
G1TPR7_RABITSmall nuclear ribonucleoprotein-associated protein. (240 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (304 aa)
RCAN2Regulator of calcineurin 2. (218 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
G1TT13_RABITBZIP domain-containing protein. (136 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
G1TUI3_RABITUncharacterized protein. (180 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (472 aa)
GPS2G protein pathway suppressor 2. (327 aa)
ZDHHC20Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (382 aa)
IL17RAInterleukin 17 receptor A. (860 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa)
G1U118_RABITUncharacterized protein. (434 aa)
ENSOCUP00000023088annotation not available (126 aa)
VPS39VPS39 subunit of HOPS complex. (885 aa)
SV2CSynaptic vesicle glycoprotein 2C. (722 aa)
G1U611_RABITUncharacterized protein. (191 aa)
G1U7T7_RABITSmall nuclear ribonucleoprotein-associated protein. (218 aa)
RANBP6Uncharacterized protein. (75 aa)
CHMP1ACharged multivesicular body protein 1A. (193 aa)
G1U996_RABITChromo domain-containing protein. (137 aa)
RHBDF1Rhomboid 5 homolog 1. (914 aa)
U3KMN0_RABITUncharacterized protein. (144 aa)
TGFBRAP1Transforming growth factor beta receptor associated protein 1. (927 aa)
ACP1LMWPc domain-containing protein. (244 aa)
CNBPUncharacterized protein. (177 aa)
ENSOCUP00000031112WH2 domain-containing protein. (410 aa)
RPN2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (647 aa)
NMIN-myc and STAT interactor. (367 aa)
ENSOCUP00000031561LMWPc domain-containing protein. (78 aa)
ZDHHC1Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (495 aa)
CRBNCereblon. (491 aa)
KPNA7Importin subunit alpha; Functions in nuclear protein import. (529 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2107 aa)
ENSOCUP00000035366IL17R_fnIII_D1 domain-containing protein. (331 aa)
SRPK1SRSF protein kinase 1. (829 aa)
TUFMTu translation elongation factor, mitochondrial. (475 aa)
PDZD3PDZ domain containing 3. (647 aa)
ENSOCUP00000036385Uncharacterized protein. (364 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (530 aa)
ZDHHC3Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (400 aa)
HAVCR2Uncharacterized protein. (530 aa)
ENSOCUP00000037105Uncharacterized protein. (78 aa)
RHBDF2Rhomboid 5 homolog 2. (849 aa)
ENSOCUP00000038330Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (205 aa)
ENSOCUP00000038512Uncharacterized protein. (161 aa)
LARP1La ribonucleoprotein domain family member 1. (1261 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (732 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (897 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (453 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (523 aa)
CHMP1BCharged multivesicular body protein 1B. (209 aa)
ELK1ETS transcription factor ELK1. (512 aa)
LOC100356234LMWPc domain-containing protein. (158 aa)
ENSOCUP00000044275Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (600 aa)
PACS1Phosphofurin acidic cluster sorting protein 1. (918 aa)
ANTXR1ANTXR cell adhesion molecule 1. (575 aa)
ENSOCUP00000045000LMWPc domain-containing protein. (98 aa)
ANTXR2Anthrax toxin receptor; Belongs to the ATR family. (523 aa)
ENSOCUP00000045820Uncharacterized protein. (424 aa)
RNF135B30.2/SPRY domain-containing protein. (250 aa)
IL17RCInterleukin 17 receptor C. (770 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (698 aa)
TRIM4Tripartite motif containing 4. (475 aa)
LOC100353286Uncharacterized protein. (465 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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