Your Input: | |||||
UBE2D1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1132 aa) | ||||
SYK | Tyrosine-protein kinase. (630 aa) | ||||
G1TZL0_RABIT | Ubiquitin-like domain-containing protein. (171 aa) | ||||
G1U1I7_RABIT | Uncharacterized protein. (91 aa) | ||||
UBE2D2 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (317 aa) | ||||
ENSOCUP00000030350 | Skp1_POZ domain-containing protein. (86 aa) | ||||
ENSOCUP00000030467 | Uncharacterized protein. (229 aa) | ||||
CSF3R | Colony stimulating factor 3 receptor. (1027 aa) | ||||
ELOC | Elongin C; Belongs to the SKP1 family. (112 aa) | ||||
ENSOCUP00000034915 | Uncharacterized protein. (176 aa) | ||||
TYK2 | Non-specific protein-tyrosine kinase. (1065 aa) | ||||
UBB | Ubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11- [...] (288 aa) | ||||
G1SG29_RABIT | Skp1_POZ domain-containing protein. (72 aa) | ||||
G1SIQ0_RABIT | UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa) | ||||
LYN | Tyrosine-protein kinase. (636 aa) | ||||
G1SK22_RABIT | Ubiquitin-like domain-containing protein. (188 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1151 aa) | ||||
CSF3 | Colony stimulating factor 3. (204 aa) | ||||
ELOB | Elongin B. (118 aa) | ||||
CUL5 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] (780 aa) |