16 items (Oryctolagus cuniculus) - STRING interaction network

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Your Input:
	G1TC56_RABIT	TGFb_propeptide domain-containing protein. (168 aa)
	IL6	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
	SAA1	Serum amyloid A-1 protein; Major acute phase protein; Belongs to the SAA family. (258 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa)
	MMP9	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). (707 aa)
	BGN	Biglycan; May be involved in collagen fiber assembly. (394 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	CP	Ceruloplasmin; Belongs to the multicopper oxidase family. (1098 aa)
	CRISP3	Cysteine rich secretory protein 3; Belongs to the CRISP family. (254 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)
	CCN2	Cellular communication network factor 2. (437 aa)
	ORM1	Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction. (322 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	LUM	Lumican. (338 aa)
	FN1	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2427 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGN	CCN2	ENSOCUP00000026470	ENSOCUP00000002454	Biglycan; May be involved in collagen fiber assembly.	Cellular communication network factor 2.	0.608
BGN	ENSOCUP00000037329	ENSOCUP00000026470	ENSOCUP00000037329	Biglycan; May be involved in collagen fiber assembly.	TGFb_propeptide domain-containing protein.	0.617
BGN	ENSOCUP00000044284	ENSOCUP00000026470	ENSOCUP00000044284	Biglycan; May be involved in collagen fiber assembly.	TGFb_propeptide domain-containing protein.	0.617
BGN	FN1	ENSOCUP00000026470	ENSOCUP00000008718	Biglycan; May be involved in collagen fiber assembly.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.852
BGN	G1TC56_RABIT	ENSOCUP00000026470	ENSOCUP00000014344	Biglycan; May be involved in collagen fiber assembly.	TGFb_propeptide domain-containing protein.	0.440
BGN	IL1B	ENSOCUP00000026470	ENSOCUP00000021869	Biglycan; May be involved in collagen fiber assembly.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.500
BGN	IL6	ENSOCUP00000026470	ENSOCUP00000017266	Biglycan; May be involved in collagen fiber assembly.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.486
BGN	LOC103345451	ENSOCUP00000026470	ENSOCUP00000031740	Biglycan; May be involved in collagen fiber assembly.	TGFb_propeptide domain-containing protein.	0.617
BGN	LUM	ENSOCUP00000026470	ENSOCUP00000004852	Biglycan; May be involved in collagen fiber assembly.	Lumican.	0.811
BGN	MMP9	ENSOCUP00000026470	ENSOCUP00000025066	Biglycan; May be involved in collagen fiber assembly.	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).	0.582
CCN2	BGN	ENSOCUP00000002454	ENSOCUP00000026470	Cellular communication network factor 2.	Biglycan; May be involved in collagen fiber assembly.	0.608
CCN2	ENSOCUP00000037329	ENSOCUP00000002454	ENSOCUP00000037329	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	ENSOCUP00000044284	ENSOCUP00000002454	ENSOCUP00000044284	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	FN1	ENSOCUP00000002454	ENSOCUP00000008718	Cellular communication network factor 2.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.654
CCN2	G1TC56_RABIT	ENSOCUP00000002454	ENSOCUP00000014344	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.841
CCN2	IL1B	ENSOCUP00000002454	ENSOCUP00000021869	Cellular communication network factor 2.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.659
CCN2	IL6	ENSOCUP00000002454	ENSOCUP00000017266	Cellular communication network factor 2.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.707
CCN2	LOC103345451	ENSOCUP00000002454	ENSOCUP00000031740	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	LUM	ENSOCUP00000002454	ENSOCUP00000004852	Cellular communication network factor 2.	Lumican.	0.414
CCN2	MMP9	ENSOCUP00000002454	ENSOCUP00000025066	Cellular communication network factor 2.	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).	0.823