STRINGSTRING
SPIB SPIB IGLL1 IGLL1 SDC1 SDC1 ID2 ID2 CD5 CD5 NCK2 NCK2 CD4 CD4 CD19 CD19 IL7 IL7 PREB PREB NCK1 NCK1 EBF1 EBF1 PAX5 PAX5 CCND2 CCND2 SYK SYK TCF12 TCF12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPIBETS domain-containing protein. (158 aa)
IGLL1Lambda5. (208 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (401 aa)
ID2Inhibitor of DNA binding 2. (109 aa)
CD5Uncharacterized protein. (488 aa)
NCK2Cytoplasmic protein. (380 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
CD19CD19 molecule. (573 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
PREBProlactin regulatory element binding. (418 aa)
NCK1Cytoplasmic protein. (377 aa)
EBF1EBF transcription factor 1. (591 aa)
PAX5Paired box 5. (371 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (431 aa)
SYKTyrosine-protein kinase. (630 aa)
TCF12Transcription factor 12. (675 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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