16 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BACE1	Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
	LRRTM1	Leucine rich repeat transmembrane neuronal 1. (574 aa)
	NRXN1	Neurexin 1. (1507 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (591 aa)
	GPHN	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (750 aa)
	NLGN1	Neuroligin 1. (823 aa)
	EPHB3	EPH receptor B3. (1075 aa)
	SLITRK1	SLIT and NTRK like family member 1. (706 aa)
	SYN1	Synapsin I. (668 aa)
	APP	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (769 aa)
	NLGN3	Neuroligin 3. (828 aa)
	NTNG1	Netrin G1. (539 aa)
	SLITRK2	SLIT and NTRK like family member 2. (845 aa)
	EPHB1	Receptor protein-tyrosine kinase. (984 aa)
	LRRTM3	Leucine rich repeat transmembrane neuronal 3. (581 aa)
	NLGN2	Neuroligin 2. (823 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	BACE1	ENSOCUP00000009130	ENSOCUP00000025190	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Beta-secretase 1; Belongs to the peptidase A1 family.	0.997
APP	NLGN1	ENSOCUP00000009130	ENSOCUP00000044921	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Neuroligin 1.	0.454
APP	NRXN1	ENSOCUP00000009130	ENSOCUP00000034839	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Neurexin 1.	0.402
APP	SYN1	ENSOCUP00000009130	ENSOCUP00000017552	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Synapsin I.	0.622
BACE1	APP	ENSOCUP00000025190	ENSOCUP00000009130	Beta-secretase 1; Belongs to the peptidase A1 family.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.997
GPHN	LRRTM1	ENSOCUP00000041866	ENSOCUP00000027450	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Leucine rich repeat transmembrane neuronal 1.	0.559
GPHN	LRRTM4	ENSOCUP00000041866	ENSOCUP00000040287	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Leucine rich repeat transmembrane neuronal 4.	0.608
GPHN	NLGN1	ENSOCUP00000041866	ENSOCUP00000044921	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Neuroligin 1.	0.796
GPHN	NLGN2	ENSOCUP00000041866	ENSOCUP00000004804	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Neuroligin 2.	0.945
GPHN	NLGN3	ENSOCUP00000041866	ENSOCUP00000022184	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Neuroligin 3.	0.731
GPHN	NRXN1	ENSOCUP00000041866	ENSOCUP00000034839	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Neurexin 1.	0.890
GPHN	SYN1	ENSOCUP00000041866	ENSOCUP00000017552	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Synapsin I.	0.702
LRRTM1	GPHN	ENSOCUP00000027450	ENSOCUP00000041866	Leucine rich repeat transmembrane neuronal 1.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.559
LRRTM1	NLGN1	ENSOCUP00000027450	ENSOCUP00000044921	Leucine rich repeat transmembrane neuronal 1.	Neuroligin 1.	0.758
LRRTM1	NLGN2	ENSOCUP00000027450	ENSOCUP00000004804	Leucine rich repeat transmembrane neuronal 1.	Neuroligin 2.	0.658
LRRTM1	NLGN3	ENSOCUP00000027450	ENSOCUP00000022184	Leucine rich repeat transmembrane neuronal 1.	Neuroligin 3.	0.675
LRRTM1	NRXN1	ENSOCUP00000027450	ENSOCUP00000034839	Leucine rich repeat transmembrane neuronal 1.	Neurexin 1.	0.818
LRRTM1	NTNG1	ENSOCUP00000027450	ENSOCUP00000025161	Leucine rich repeat transmembrane neuronal 1.	Netrin G1.	0.643
LRRTM3	NLGN1	ENSOCUP00000003478	ENSOCUP00000044921	Leucine rich repeat transmembrane neuronal 3.	Neuroligin 1.	0.439
LRRTM3	NLGN2	ENSOCUP00000003478	ENSOCUP00000004804	Leucine rich repeat transmembrane neuronal 3.	Neuroligin 2.	0.426