Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE | ACE2 | ENSOCUP00000022251 | ENSOCUP00000015275 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Angiotensin-converting enzyme. | 0.523 |
| ACE | CCL2 | ENSOCUP00000022251 | ENSOCUP00000015636 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] | 0.648 |
| ACE | ENSOCUP00000037329 | ENSOCUP00000022251 | ENSOCUP00000037329 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | TGFb_propeptide domain-containing protein. | 0.561 |
| ACE | ENSOCUP00000044284 | ENSOCUP00000022251 | ENSOCUP00000044284 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | TGFb_propeptide domain-containing protein. | 0.561 |
| ACE | G1TC56_RABIT | ENSOCUP00000022251 | ENSOCUP00000014344 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | TGFb_propeptide domain-containing protein. | 0.553 |
| ACE | G1TJG6_RABIT | ENSOCUP00000022251 | ENSOCUP00000017094 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.431 |
| ACE | G1TYG1_RABIT | ENSOCUP00000022251 | ENSOCUP00000022125 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.408 |
| ACE | GAPDH | ENSOCUP00000022251 | ENSOCUP00000044112 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.661 |
| ACE | LOC103345451 | ENSOCUP00000022251 | ENSOCUP00000031740 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | TGFb_propeptide domain-containing protein. | 0.561 |
| ACE | REN | ENSOCUP00000022251 | ENSOCUP00000017597 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Renin; Belongs to the peptidase A1 family. | 0.981 |
| ACE2 | ACE | ENSOCUP00000015275 | ENSOCUP00000022251 | Angiotensin-converting enzyme. | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | 0.523 |
| ACE2 | CCL2 | ENSOCUP00000015275 | ENSOCUP00000015636 | Angiotensin-converting enzyme. | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] | 0.695 |
| ACE2 | ENSOCUP00000037329 | ENSOCUP00000015275 | ENSOCUP00000037329 | Angiotensin-converting enzyme. | TGFb_propeptide domain-containing protein. | 0.582 |
| ACE2 | ENSOCUP00000044284 | ENSOCUP00000015275 | ENSOCUP00000044284 | Angiotensin-converting enzyme. | TGFb_propeptide domain-containing protein. | 0.582 |
| ACE2 | G1TC56_RABIT | ENSOCUP00000015275 | ENSOCUP00000014344 | Angiotensin-converting enzyme. | TGFb_propeptide domain-containing protein. | 0.569 |
| ACE2 | G1TJG6_RABIT | ENSOCUP00000015275 | ENSOCUP00000017094 | Angiotensin-converting enzyme. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.472 |
| ACE2 | G1TYG1_RABIT | ENSOCUP00000015275 | ENSOCUP00000022125 | Angiotensin-converting enzyme. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.452 |
| ACE2 | GAPDH | ENSOCUP00000015275 | ENSOCUP00000044112 | Angiotensin-converting enzyme. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.707 |
| ACE2 | LOC103345451 | ENSOCUP00000015275 | ENSOCUP00000031740 | Angiotensin-converting enzyme. | TGFb_propeptide domain-containing protein. | 0.582 |
| ACE2 | LOC103351595 | ENSOCUP00000015275 | ENSOCUP00000037472 | Angiotensin-converting enzyme. | Angiotensin-converting enzyme. | 0.490 |
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